Serum leptin and habitual fatty acid dietary intake in patients with type 1 diabetes mellitus.

abstract：:AMP-activated protein kinase (AMPK) is a cellular gauge that is activated under conditions, such as low energy, increasing energy production and reducing energy waste. Centrally, the AMPK pathway is a canonical route regulating energy homeostasis, by integrating peripheral signals, such as hormones and metabolites, wi...

journal_title：European journal of endocrinology

authors： López M

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:Adiponectin and resistin have been linked to inflammation, endothelial dysfunction, and/or insulin secretion or resistance. It remains to be elucidated which of these adipokines is associated primarily with biomarkers of all or only some of these categories, i.e. biomarkers of inflammation, endothelial dysfun...

journal_title：European journal of endocrinology

authors： Fargnoli JL,Sun Q,Olenczuk D,Qi L,Zhu Y,Hu FB,Mantzoros CS

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:Thyroidal production of triiodothyronine (T(3)) is absent in patients who have undergone total thyroidectomy. Therefore, relative T(3) deficiency may occur during postoperative levothyroxine (L-T(4)) therapy. The objective of this study was to evaluate how the individual serum T(3) level changes between preop...

journal_title：European journal of endocrinology

authors： Ito M,Miyauchi A,Morita S,Kudo T,Nishihara E,Kihara M,Takamura Y,Ito Y,Kobayashi K,Miya A,Kubota S,Amino N

更新日期：2012-09-01 00:00:00

abstract：Objective:Children with Prader-Willi syndrome (PWS) have mild to moderate cognitive impairment. Short-term studies showed positive effects of growth hormone (GH) on cognitive development. This study investigated the effects of 8 years of GH on cognitive development in children with PWS. We also investigated whether sta...

journal_title：European journal of endocrinology

authors： Donze SH,Damen L,Mahabier EF,Hokken-Koelega ACS

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:Glucocorticoids stimulate several steps in red blood cell (RBC) development; however, little is known on changes in erythroid parameters in patients with Cushing's disease. The aim of this study was to assess both RBC and white blood cell (WBC) parameters in a large cohort of patients with Cushing's disease a...

journal_title：European journal of endocrinology

authors： Ambrogio AG,De Martin M,Ascoli P,Cavagnini F,Pecori Giraldi F

更新日期：2014-02-04 00:00:00

abstract：BACKGROUND:Epidemiological studies suggest that hypopituitary patients have an increased risk for cardiovascular mortality. The dyslipidaemia associated with this condition is often characterised by an increase in total cholesterol (TC) and low-density lipoprotein (LDL) cholesterol (LDL-C) and may contribute to these f...

journal_title：European journal of endocrinology

authors： Christ ER,Cummings MH,Stolinski M,Jackson N,Lumb PJ,Wierzbicki AS,Sönksen PH,Russell-Jones DL,Umpleby AM

更新日期：2006-03-01 00:00:00

abstract：INTRODUCTION:The fetus is most vulnerable to severe iodine deficiency and hypothyroidism during pregnancy. The effects of mild iodine deficiency and subclinical hypothyroidism are poorly known. The present study assesses the association between thyroid hormones (TH)s and urinary iodine concentration (UIC) in healthy pr...

journal_title：European journal of endocrinology

authors： Alvarez-Pedrerol M,Guxens M,Mendez M,Canet Y,Martorell R,Espada M,Plana E,Rebagliato M,Sunyer J

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:Primary aldosteronism (PA) has deleterious effects on kidney function independent of blood pressure levels. Up to now, data on effectiveness of different PA therapies regarding renal function are scarce. DESIGN AND METHODS:This prospective multi-center study included 29 patients with newly diagnosed PA evalu...

journal_title：European journal of endocrinology

authors： Fourkiotis V,Vonend O,Diederich S,Fischer E,Lang K,Endres S,Beuschlein F,Willenberg HS,Rump LC,Allolio B,Reincke M,Quinkler M,Mephisto Study Group.

更新日期：2012-12-10 00:00:00

abstract：OBJECTIVE:Untreated hypothyroidism is common in iodine-replete areas. Frequent thyroid function testing and use of levothyroxine treatment for subclinical hypothyroidism suggest that the prevalence may have decreased. Therefore, in this study, we examined changes in the prevalence of hypothyroidism in a Norwegian count...

journal_title：European journal of endocrinology

authors： Asvold BO,Vatten LJ,Bjøro T

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:To investigate whether patients with Addison's disease and polyendocrine syndromes have undiagnosed autoimmune polyendocrine syndrome type I (APS I). MATERIALS AND METHODS:Forty patients with clinical manifestations resembling APS I and with autoantibodies typical of this condition were screened for Norwegia...

journal_title：European journal of endocrinology

authors： Bøe AS,Knappskog PM,Myhre AG,Sørheim JI,Husebye ES

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:The type 2 deiodinase (D2) is a key enzyme for intracellular triiodothyronine (T(3)) generation. A single-nucleotide polymorphism in D2 (Thr92Ala) has been associated with increased insulin resistance in nondiabetic and type 2 diabetes (DM2) subjects. Our aim was to evaluate whether the D2 Thr92Ala polymorphi...

journal_title：European journal of endocrinology

authors： Dora JM,Machado WE,Rheinheimer J,Crispim D,Maia AL

更新日期：2010-09-01 00:00:00

abstract：:To assess the metabolic effects of thyroid disease, body composition was determined by bioimpedance analysis (BIA) in 72 patients with untreated hyperthyroidism (mean age 48.7 +/- 1.9 years) and 26 patients with untreated hypothyroidism (63.8 +/- 3.4 years). Bioelectrical whole body resistance (R) and reactance (Xc) w...

journal_title：European journal of endocrinology

authors： Seppel T,Kosel A,Schlaghecke R

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:Recent observational studies have established progression and recurrence rates of pituitary adenomas. However, it is still unknown how individual pituitary adenomas grow over years and whether growth kinetics follow a distinct growth model. The objective of this study was to define a growth model for non-func...

journal_title：European journal of endocrinology

authors： Honegger J,Zimmermann S,Psaras T,Petrick M,Mittelbronn M,Ernemann U,Reincke M,Dietz K

更新日期：2008-03-01 00:00:00

abstract：:Design Hypercortisolism during pregnancy is a risk factor for prematurity. Long-term exposure to hypercortisolism may lead to permanent comorbidities, such as hypertension or diabetes, even after remission. Our aim was to determine whether women with a history of Cushing's disease (and being eu-, hypo- or hypercortiso...

journal_title：European journal of endocrinology

authors： Hochman C,Cristante J,Geslot A,Salenave S,Sonnet E,Briet C,Bachelot A,Chevalier N,Gilly O,Brue T,Hadjadj S,Kerlan V,Chanson P,Vezzosi D,Chabre O,Drui DD,Castinetti FF

更新日期：2021-01-01 00:00:00

abstract：:Four groups(N = 3 per group) of juvenile rhesus monkeys (Macaca mulatta, 14-20 months old) received either vehicle or highly purified human follicle-stimulating hormone (FSH; 10 IU kg-1 day-1), human chorionic gonadotropin (hCG; 250 IU every alternate day) or both hormones for a period of 4 weeks. Testicular volume an...

journal_title：European journal of endocrinology

authors： Schlatt S,Arslan M,Weinbauer GF,Behre HM,Nieschlag E

更新日期：1995-08-01 00:00:00

abstract：OBJECTIVE:Congenital hypothyroidism (CH), the most common neonatal metabolic disorder, is characterized by impaired neurodevelopment. Although several candidate genes have been associated with CH, comprehensive screening of causative genes has been limited. DESIGN AND METHODS:One hundred ten patients with primary CH w...

journal_title：European journal of endocrinology

authors： Sun F,Zhang JX,Yang CY,Gao GQ,Zhu WB,Han B,Zhang LL,Wan YY,Ye XP,Ma YR,Zhang MM,Yang L,Zhang QY,Liu W,Guo CC,Chen G,Zhao SX,Song KY,Song HD

更新日期：2018-06-01 00:00:00

abstract：:Bone mineral density (BMD), bone mineral content and body composition were determined in 47 middle-aged (mean age 47.9 +/- 1.1 years) women with Turner's syndrome. Bone mineral density was measured in the forearm, femoral neck and total body. The women investigated had a BMD lower than the normal mean. When expressed ...

journal_title：European journal of endocrinology

authors： Sylvén L,Hagenfeldt K,Ringertz H

更新日期：1995-01-01 00:00:00

abstract：:There are close interactions between the adipocyte-derived hormone, leptin, and the anterior pituitary, especially the hypothalamic-pituitary-adrenal (HPA) axis. We investigated the relationship between the sympathetic adrenergic system and serum leptin levels, dependent on the function of anterior pituitary hormone a...

journal_title：European journal of endocrinology

authors： Schafroth U,Godang K,Ueland T,Bollerslev J

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:Activin is a growth and differentiation factor of many cell types, and has recently been implicated in inflammatory processes. Clinical data linking activin and its binding protein, follistatin (FS), are lacking. We measured serum levels of activin and FS in patients diagnosed with septicemia. PATIENTS AND M...

journal_title：European journal of endocrinology

authors： Michel U,Ebert S,Phillips D,Nau R

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:Recent trials suggest that using ergot-derived dopamine agonists such as cabergoline in the treatment of Parkinson's disease is associated with an increased risk of valvular heart disease. However, the dose of cabergoline used to treat hyperprolactinaemia is considerably less than that used in Parkinson's dis...

journal_title：European journal of endocrinology

authors： Wakil A,Rigby AS,Clark AL,Kallvikbacka-Bennett A,Atkin SL

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:For patients who remain hypothyroid despite the administration of what would seem adequate doses of levothyroxine (L-T4), the underlying cause can be difficult to determine. The possibility of a biological cause should first be explored; however, in the majority of cases, poor adherence to medication is likel...

journal_title：European journal of endocrinology

authors： Walker JN,Shillo P,Ibbotson V,Vincent A,Karavitaki N,Weetman AP,Wass JA,Allahabadia A

更新日期：2013-05-10 00:00:00

abstract：CONTEXT:The TIMES2 (testosterone replacement in hypogonadal men with either metabolic syndrome or type 2 diabetes) study reported beneficial effects of testosterone replacement therapy (TRT) on insulin resistance and other variables in men with diabetes or metabolic syndrome. The androgen receptor CAG repeat polymorphi...

journal_title：European journal of endocrinology

authors： Stanworth RD,Akhtar S,Channer KS,Jones TH

更新日期：2013-12-21 00:00:00

abstract：:The initial management of large non-functioning pituitary adenomas is surgical debulking. In some cases, postoperative radiotherapy (RT) is administered in order to reduce the likelihood of tumour regrowth. Historically, there have been concerns surrounding a number of potentially significant complications of pituitar...

journal_title：European journal of endocrinology

authors： Boelaert K,Gittoes NJ

更新日期：2001-06-01 00:00:00

abstract：CONTEXT AND OBJECTIVE:Arterial stimulation and venous sampling (ASVS) is an important technique for localizing insulinoma. The principle behind ASVS is that insulin secretion is promoted from insulinoma cells by the injection of calcium into the insulinoma-feeding artery. However, the mechanism for ASVS-induced insulin...

journal_title：European journal of endocrinology

authors： Ono Y,Oda N,Ishihara S,Shimomura A,Hayakawa N,Suzuki A,Horiguchi A,Senda T,Miyakawa S,Itoh M

更新日期：2008-07-01 00:00:00

abstract：Background:Autosomal dominant neurohypophyseal diabetes insipidus (adNDI) is caused by arginine vasopressin (AVP) deficiency resulting from mutations in the AVP-NPII gene encoding the AVP preprohormone. Aim:To describe the clinical and molecular features of Italian unrelated families with central diabetes insipidus. ...

journal_title：European journal of endocrinology

authors： Patti G,Scianguetta S,Roberti D,Di Mascio A,Balsamo A,Brugnara M,Cappa M,Casale M,Cavarzere P,Cipriani S,Corbetta S,Gaudino R,Iughetti L,Martini L,Napoli F,Peri A,Salerno MC,Salerno R,Passeri E,Maghnie M,Perrotta

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:To determine the frequency of mutations of the gonadotropin-releasing hormone receptor (GnRHR) and of the G protein-coupled receptor 54 (GPR54) genes in normosmic idiopathic hypogonadotropic hypogonadism (IHH). METHODS:In a retrospective study we analyzed the GnRHR and the GPR54 genes of 45 IHH patients and ...

journal_title：European journal of endocrinology

authors： Lanfranco F,Gromoll J,von Eckardstein S,Herding EM,Nieschlag E,Simoni M

更新日期：2005-12-01 00:00:00

abstract：CONTEXT:The urea cycle is a rate-limiting step for amino acid nitrogen elimination. The rate of urea synthesis is a true indicator of whole-body protein catabolism. Testosterone reduces protein and nitrogen loss. The effect of testosterone on hepatic urea synthesis in humans has not been studied. OBJECTIVE:To determin...

journal_title：European journal of endocrinology

authors： Lam T,Poljak A,McLean M,Bahl N,Ho KKY,Birzniece V

更新日期：2017-04-01 00:00:00

abstract：INTRODUCTION:In an animal model of acromegaly (PEPCK-hGH transgenic mice), low systemic levels of ghrelin have been observed compared with normal mice. We hypothesized that systemic circulating ghrelin levels are also decreased in humans with active acromegaly and that the contribution of central ghrelin production to ...

journal_title：European journal of endocrinology

authors： van der Toorn FM,Janssen JA,de Herder WW,Broglio F,Ghigo E,van der Lely AJ

更新日期：2002-08-01 00:00:00

abstract：:Amiodarone (AMD) is a powerful anti-arrhythmic drug used for the treatment of a wide variety of cardiac arrhythmias and its most striking feature is its high iodine content. Thyroid dysfunction is a limiting side-effect of the drug and both AMD-induced hypothyroidism (AIH) and AMD-induced thyrotoxicosis (AIT) are repo...

journal_title：European journal of endocrinology

authors： Pitsiavas V,Smerdely P,Boyages SC

更新日期：1999-03-01 00:00:00

abstract：:Papillary craniopharyngioma (PCP) is an intracranial tumor that results in high levels of morbidity. We recently demonstrated that the vast majority of these tumors harbor the oncogenic BRAF V600E mutation. The pathologic diagnosis of PCP can now be confirmed using mutation specific immunohistochemistry and targeted g...

journal_title：European journal of endocrinology

authors： Brastianos PK,Santagata S

更新日期：2016-04-01 00:00:00