Dendritic spikes and their influence on extracellular calcium signaling.

abstract：:1. The discharge of individual neurons in the visual cortex and lateral geniculate nucleus (LGN) of anesthetized and paralyzed cats and kittens was examined for the presence of oscillatory activity. Neural firing was evoked through the monoptic or dichoptic presentation of drifting gratings and random sequences of fla...

journal_title：Journal of neurophysiology

authors： Ghose GM,Freeman RD

更新日期：1992-11-01 00:00:00

abstract：:Long-term depression (LTD) was induced in neocortical layer 5 pyramidal connections by pairing presynaptic firing with subthreshold postsynaptic depolarization (dLTD) or via a spike-timing protocol (tLTD). Like tLTD, dLTD reduced short-term depression and increased the coefficient of variation consistent with a presyn...

journal_title：Journal of neurophysiology

authors： Sjöström PJ,Turrigiano GG,Nelson SB

更新日期：2004-12-01 00:00:00

abstract：:During seizure-like events (SLEs), intracellular Ca2+ concentration ([Ca2+]i) increases causing depolarization of the mitochondrial membrane and subsequent intramitochondrial accumulation of Ca2+. Mitochondrial depolarization results in an interruption of oxidative phosphorylation and increase in reactive oxygen speci...

journal_title：Journal of neurophysiology

authors： Schuchmann S,Buchheim K,Meierkord H,Heinemann U

更新日期：1999-01-01 00:00:00

abstract：:1. We investigated the glycine-induced response in ventromedial hypothalamic (VMH) neurons freshly dissociated from 8- to 12-day-old rats using the nystatin and gramicidin perforated patch recording modes. The nystatin-formed pores in the plasma membrane are permeable for both monovalent cations and anions, whereas th...

journal_title：Journal of neurophysiology

authors： Abe Y,Furukawa K,Itoyama Y,Akaike N

更新日期：1994-10-01 00:00:00

abstract：:1. The electrophysiological and pharmacological properties of slow afterpotentials in large layer V neurons from cat sensorimotor cortex were studied in an in vitro slice preparation using intracellular recording and single-microelectrode voltage clamp. These properties were used to assess the role of afterpotential m...

journal_title：Journal of neurophysiology

authors： Schwindt PC,Spain WJ,Foehring RC,Chubb MC,Crill WE

更新日期：1988-02-01 00:00:00

abstract：:When they are 1-2 mo old, domesticated Mongolian gerbils begin having initially mild seizures which become more severe with age. To evaluate the development of this increasing seizure severity, we obtained field potential responses of the dentate gyrus to paired-pulse stimulation of the perforant path during seizures....

journal_title：Journal of neurophysiology

authors： Buckmaster PS,Wong EH

更新日期：2002-08-01 00:00:00

abstract：:Many sensory brain regions are characterized by extensive local network interactions. However, we know relatively little about the contribution of this microcircuitry to sensory coding. Detailed analyses of neuronal microcircuitry are usually performed in vitro, whereas sensory processing is typically studied by recor...

journal_title：Journal of neurophysiology

authors： Ma X,Kohashi T,Carlson BA

更新日期：2013-07-01 00:00:00

abstract：:The ventral pallidum (VP) is a key structure in brain mesocorticolimbic reward circuits that mediate "liking" reactions to sensory pleasures. Do firing patterns in VP actually code sensory pleasure? Strong evidence for hedonic coding requires showing that neural signals track positive increases in sensory pleasure or ...

journal_title：Journal of neurophysiology

authors： Tindell AJ,Smith KS,Peciña S,Berridge KC,Aldridge JW

更新日期：2006-11-01 00:00:00

abstract：:Dopamine neurons of the ventral tegmental area (VTA) signal the occurrence of a reward-predicting conditioned stimulus (CS) with a subsecond duration increase in post-CS firing rate. Important theories about reward-prediction error and reward expectancy have been informed by the substantial number of studies that have...

journal_title：Journal of neurophysiology

authors： Totah NK,Kim Y,Moghaddam B

更新日期：2013-07-01 00:00:00

abstract：:Exercise, in the form of moderate daily treadmill training following nerve transection and repair leads to enhanced axon regeneration, but its effect on functional recovery is less well known. Female rats were exercised by walking continuously, at a slow speed (10 m/min), for 1 h/day on a level treadmill, beginning 3 ...

journal_title：Journal of neurophysiology

authors： Boeltz T,Ireland M,Mathis K,Nicolini J,Poplavski K,Rose SJ,Wilson E,English AW

更新日期：2013-06-01 00:00:00

abstract：:The perforant path forms a monosynaptic connection between the cells of layer II of the entorhinal cortex and the pyramidal cells in hippocampal area CA3. Although this projection is prominent anatomically, very little is known about the physiological properties of this input. The distal location of these synapses sug...

journal_title：Journal of neurophysiology

authors： Urban NN,Henze DA,Barrionuevo G

更新日期：1998-09-01 00:00:00

abstract：:It is not known how changes in skin mechanics affect the responses of cutaneous mechanoreceptors in the finger pads to compression forces. We used venous occlusion to change the stiffness of the fingers and investigated whether this influenced the firing of low-threshold mechanoreceptors to surfaces of differing stiff...

journal_title：Journal of neurophysiology

authors： Hudson KM,Condon M,Ackerley R,McGlone F,Olausson H,Macefield VG,Birznieks I

更新日期：2015-10-01 00:00:00

abstract：:The exercise pressor reflex (EPR) is generated by group III and IV muscle afferents during exercise to increase cardiovascular function. Muscle contraction is triggered by ACh, which is metabolized into choline that could serve as a signal of exercise-induced activity. We demonstrate that ACh can induce current in mus...

journal_title：Journal of neurophysiology

authors： Baxter JC,Ramachandra R,Mayne DR,Elmslie KS

更新日期：2014-09-15 00:00:00

abstract：:1. Teased axon recordings were made from 167 spontaneously active A beta- and A delta-afferents that ended in sciatic nerve end neuromas of 6-12 days standing. When challenged with a standard bolus of systemically applied adrenaline, 100 (60%) responded, either with an increase in baseline firing frequency (excitation...

journal_title：Journal of neurophysiology

authors： Chen Y,Michaelis M,Janig W,Devor M

更新日期：1996-12-01 00:00:00

abstract：:Swallow-evoked potentials in the preganglionic vagal fibers were studied using the single-fiber recording technique in anesthetized opossums. Swallows were evoked by tactile pharyngeal stimulation or electrical stimulation of the cut central end of the superior laryngeal nerve (SLN). Swallowing activity was recorded b...

journal_title：Journal of neurophysiology

authors： Gidda JS,Goyal RK

更新日期：1984-12-01 00:00:00

abstract：:1. Compartmental modeling experiments were carried out in an anatomically characterized neocortical pyramidal cell to study the integrative behavior of a complex dendritic tree containing active membrane mechanisms. Building on a previously presented hypothesis, this work provides further support for a novel principle...

journal_title：Journal of neurophysiology

authors： Mel BW

更新日期：1993-09-01 00:00:00

abstract：:1. We have investigated the electrical properties of neurons acutely dissociated from the substantia nigra zona compacta (SNZC) of the postnatal rat with whole cell patch-clamp recordings. Retrogradely labeled nigrostriatal neurons were identified with the use of rhodamine-labeled fluorescent latex microspheres. Over ...

journal_title：Journal of neurophysiology

authors： Silva NL,Pechura CM,Barker JL

更新日期：1990-07-01 00:00:00

abstract：:Synapsin is a synaptic vesicle-associated protein implicated in the regulation of vesicle trafficking and transmitter release, but its role in heterosynaptic plasticity remains elusive. Moreover, contradictory results have obscured the contribution of synapsin to homosynaptic plasticity. We previously reported that th...

journal_title：Journal of neurophysiology

authors： Fioravante D,Liu RY,Netek AK,Cleary LJ,Byrne JH

更新日期：2007-12-01 00:00:00

abstract：:1. The mismatch response, or mismatch negativity (MMN), is a neurophysiologic response to stimulus change. In humans and other animals, the MMN may underlie the ability to discriminate acoustic differences, a fundamental aspect of auditory perception. 2. This study investigated the role of the thalamus in the generati...

journal_title：Journal of neurophysiology

authors： Kraus N,McGee T,Littman T,Nicol T,King C

更新日期：1994-09-01 00:00:00

abstract：:The plant-derived insecticides have introduced a new concept in insecticide research. In response to insect attacks, some plants can release volatile sulfur compounds such as dimethyl disulfide (DMDS) in the atmosphere, which are lethal for the generalist insects. We demonstrate that DMDS induced an uncommon complex n...

journal_title：Journal of neurophysiology

authors： Dugravot S,Grolleau F,Macherel D,Rochetaing A,Hue B,Stankiewicz M,Huignard J,Lapied B

更新日期：2003-07-01 00:00:00

abstract：:Through their actions in the nucleus accumbens (NAc), kappa opioid (KOP) receptors and their endogenous ligand, dynorphin, modify behaviors associated with the administration of drugs of abuse and are regulated by exposure to such drugs. Despite their demonstrated behavioral significance, the synaptic actions of KOP r...

journal_title：Journal of neurophysiology

authors： Hjelmstad GO,Fields HL

更新日期：2003-05-01 00:00:00

abstract：:Lateral protocerebral interneurons (LPIs) in the central olfactory pathway of the freshwater crayfish Procambarus clarkii reside within the lateral protocerebrum and receive direct input from projection neurons of the olfactory midbrain. The LPIs exhibit periodic (0.5 Hz) changes in membrane potential that are imposed...

journal_title：Journal of neurophysiology

authors： Mellon D Jr,Wheeler CJ

更新日期：1999-03-01 00:00:00

abstract：:This study examined the effects of selective inactivation of the cerebellar nuclei in the cat on the control of multijoint trajectories and trajectory adaptation to avoid obstacles. Animals were restrained in a hammock and trained to perform a prehension task in which they reached to grasp a small cube of meat from a ...

journal_title：Journal of neurophysiology

authors： Martin JH,Cooper SE,Hacking A,Ghez C

更新日期：2000-04-01 00:00:00

abstract：:1. Two hundred and twenty-one spinothalamic tract (STT) neurons in the lumbar spinal cord of anesthetized monkeys were studied. The majority of the recordings were in laminae IV-VI. Thirteen of these neurons were intracellularly injected with horseradish peroxidase and histologically reconstructed. 2. A standard serie...

journal_title：Journal of neurophysiology

authors： Surmeier DJ,Honda CN,Willis WD Jr

更新日期：1988-03-01 00:00:00

abstract：:Regularly discharging vestibular-nerve afferents innervating the semicircular canals were recorded extracellularly in anesthetized chinchillas undergoing high-frequency, high-velocity sinusoidal rotations. In the range from 2 to 20 Hz, with peak velocities of 151 degrees/s at 6 Hz and 52 degrees/s at 20 Hz, 67/70 (96%...

journal_title：Journal of neurophysiology

authors： Hullar TE,Minor LB

更新日期：1999-10-01 00:00:00

abstract：:Gain-of-function variants in voltage-gated sodium channel NaV1.7 that increase firing frequency and spontaneous firing of dorsal root ganglion (DRG) neurons have recently been identified in 5-10% of patients with idiopathic small fiber neuropathy (I-SFN). Our previous in vitro observations suggest that enhanced sodium...

journal_title：Journal of neurophysiology

authors： Lee SI,Hoeijmakers JGJ,Faber CG,Merkies ISJ,Lauria G,Waxman SG

更新日期：2020-02-01 00:00:00

abstract：:Locusts have two large collision-detecting neurons, the descending contralateral movement detectors (DCMDs) that signal object approach and trigger evasive glides during flight. We sought to investigate whether vision for action, when the locust is in an aroused state rather than a passive viewer, significantly alters...

journal_title：Journal of neurophysiology

authors： Rind FC,Santer RD,Wright GA

更新日期：2008-08-01 00:00:00

abstract：:Generalization is a fundamental aspect of behavior, allowing for the transfer of knowledge from one context to another. The details of this transfer are thought to reveal how the brain represents what it learns. Generalization has been a central focus in studies of sensorimotor adaptation, and its pattern has been wel...

journal_title：Journal of neurophysiology

authors： McDougle SD,Bond KM,Taylor JA

更新日期：2017-07-01 00:00:00

abstract：:1. A network of four pairs of interneurons, HN(1)-HN(4), times the heartbeat of the medicinal leech. The following model accounts for the stable phase relationships in the network and the network's response to perturbation, entrainment, and stimulation. 2. There are two centers of oscillation, one the HN(3) pair in th...

journal_title：Journal of neurophysiology

authors： Peterson EL

更新日期：1983-03-01 00:00:00

abstract：:Successful motor performance relies on our ability to adapt to changes in the environment by learning novel mappings between motor commands and sensory outcomes. Such adaptation is thought to involve two distinct mechanisms: an implicit, error-based component linked to slow learning and an explicit, strategic componen...

journal_title：Journal of neurophysiology

authors： de Brouwer AJ,Albaghdadi M,Flanagan JR,Gallivan JP

更新日期：2018-10-01 00:00:00