The effects of ischemia on long-tract neural conduction in the spinal cord.

Abstract:

:In this experiment, the effects of ischemia on neural conduction in the monkey spinal cord were studied. In six monkeys generalized ischemia of the spinal cord was created by bleeding the animals to a hypotensive level below the lower limits of autoregulation in the spinal cord. The progressive development of spinal cord ischemia was documented by blood-flow measurement using the hydrogen clearance method. Physiological integrity of the spinal cord was monitored and recorded by the spinal evoked response. The spinal evoked response did not disappear until at least 10 minutes of profound ischemia. At levels of ischemia 20% to 25% of normal blood flow, the spinal evoked response was unchanged. It is concluded that long-tract neural conduction in the spinal cord is relatively resistant to the effects of ischemia.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Kobrine AI,Evans DE,Rizzoli HV

doi

10.3171/jns.1979.50.5.0639

subject

Has Abstract

pub_date

1979-05-01 00:00:00

pages

639-44

issue

5

eissn

0022-3085

issn

1933-0693

journal_volume

50

pub_type

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