Abstract:
:The objective of this paper is to evaluate the efficacy of various magnetic resonance imaging (MRI) sequences and the general usefulness of prenatal MRI in determining the position of the fetal liver and visualizing lung tissue in fetuses who have congenital diaphragmatic hernia (CDH). This was a retrospective review of prenatal MRI of fetuses with a confirmed diagnosis by surgery or autopsy of CDH. MRI was performed in a 1.5-Tesla magnet using fast gradient echo, half-Fourier single-shot turbo spin-echo (HASTE) and echo planar images. The presence of a chest mass, position of the stomach and liver and visualization of the lungs by MRI was noted in all fetuses. This was compared to ultrasound studies performed the same day and correlated with postnatal or autopsy studies. The fetuses were 18-36 weeks gestational age (mean 24.5 weeks). MRI diagnosed left CDH (33), right CDH (4), and bilateral CDH (1) and agreed with the postnatal diagnosis in all patients. Ultrasound (US) diagnosed left CDH (33), right CDH (2), and congenital cystic adenomatoid malformation (3). MRI changed the diagnosis in four patients. The fetal liver was easily demonstrated with MRI in all fetuses and was herniated into the chest in 25 of the 38. US diagnosed liver up in 21. Correlation with postnatal studies found MRI correctly diagnosed liver position in 37 out of 38 cases. US correctly diagnosed liver position in 32 out of 38. Both lungs could be visualized in all fetuses with MRI. MRI accurately and easily diagnoses CDH and can differentiate it from other chest masses. MRI was superior to US in demonstrating the position of the fetal liver above or below the diaphragm. MRI reliably visualized fetal lung tissue. These findings are important for counseling parents, selecting fetal surgical candidates, and estimating prognosis.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Hubbard AM,Crombleholme TM,Adzick NS,Coleman BG,Howell LJ,Meyer JS,Flake AWdoi
10.1055/s-1999-6821subject
Has Abstractpub_date
1999-01-01 00:00:00pages
407-13issue
8eissn
0735-1631issn
1098-8785journal_volume
16pub_type
杂志文章abstract::Nine patients with posthemipelvectomy with subsequent delivery of 13 living children are reported in the world's literature. This radical procedure is possible only in a modern age of intensive medical and surgical support. Additional cases can be expected in the future. We present two additional patients and three ch...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-999616
更新日期:1989-07-01 00:00:00
abstract::Arteriovenous malformations of the Vein of Galen continue to present diagnostic and therapeutic challenges in the neonatal period. Approximately 40-50% of all malformations of the Vein of Galen present in the neonatal period, usually with congestive heart failure. These neonates represent the most severe cases and are...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2000-13456
更新日期:2000-01-01 00:00:00
abstract::External cephalic version should be followed by fetal and maternal surveillance until delivery. To shorten this period of surveillance, a protocol of version at term, followed by immediate induction of labor, was adopted. The aim of the present study was to evaluate the effect of this protocol on the subsequent mode o...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994508
更新日期:1995-11-01 00:00:00
abstract::The estimation of plasma bilirubin concentration in neonates, using a transcutaneous, noninvasive jaundice meter, is significantly affected by many factors, such as gestational age, birthweight, phototherapy, and skin pigmentation. In an attempt to minimize the influence of skin color and hence circumvent the need for...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2008-1040751
更新日期:1994-05-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of pretreatment with obestatin (OB), an endogenous hormone also found in mother's milk, in experimental necrotizing enterocolitis (NEC). STUDY DESIGN:Pups were randomized into four groups: control, OB-control, NEC, and OB-NEC. NEC was induced by asphyxia and hypothermia in the NEC a...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1676491
更新日期:2019-09-01 00:00:00
abstract::Hypertensive disorders during pregnancy implicate placental pathologic conditions, which may interfere with the normal passage of alpha-fetoprotein (AFP) to the maternal blood. We compared the levels of maternal serum (MS) in early second trimester of pregnancies complicated by hypertensive disorders with those of mat...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999254
更新日期:1992-09-01 00:00:00
abstract::This communication examines the diagnostic value of the leukocyte esterase activity (LEA) test in the detection of intra-amniotic infection. Amniotic fluid from 171 consecutive patients with premature rupture of membranes (n = 149) and preterm labor (n = 22) was obtained through amniocentesis. Gram stain, bacterial an...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999657
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE: This study aimed to the assess risk of respiratory morbidity in neonates born to women with gestational diabetes mellitus (GDM) delivered after labor compared with those delivered without exposure to labor. STUDY DESIGN: This is a secondary analysis of a prospective single-center cohort study of singleton p...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1716483
更新日期:2020-09-06 00:00:00
abstract::A 27-year-old primigravida women was referred for ultrasound studies at 32 weeks' gestation because of the suspicion of fetal ventriculomegaly. Sonographic examination of the fetal brain found a marked shift of the midline, with enlarged left hemisphere and ipsilateral occipital horn, and abnormal convolutions. A 3500...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999330
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE: The acylcarnitine profile is analyzed in dried blood spots (DBS) to screen for inborn errors of metabolism. Hematocrit (Ht) is known to affect the result of quantitative analyses of DBS samples; however, the effects of Ht on the acylcarnitine profiles in DBS have not been studied in actual samples from newbo...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1721849
更新日期:2020-12-29 00:00:00
abstract::Oxygenation instability is a very common problem in the premature infant that manifests as intermittent hypoxemia episodes (HEs). These are particularly frequent in premature infants who are on mechanical ventilation beyond the first weeks after birth. However, they can also occur in spontaneously breathing infants. S...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-0038-1637760
更新日期:2018-05-01 00:00:00
abstract::Background Late-onset sepsis (LOS) in very low-birth-weight (VLBW) infants is associated with significant morbidity and mortality. Objectives To determine the incidence of LOS workup, association, and predictive value of clinical indicators leading to culture-positive versus culture-negative sepsis workup. Methods All...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0036-1579648
更新日期:2016-07-01 00:00:00
abstract::We present an unusual case of a primigravida with a viable cervical pregnancy diagnosed by transvaginal ultrasound and magnetic resonance imaging. Staggered conservative therapeutic measures included systemic high-dose Methotrexate with Folinic acid rescue followed by bilateral embolization of the uterine arteries in ...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2003-42341
更新日期:2003-07-01 00:00:00
abstract::To estimate the risk of preterm birth in asymptomatic women with twin pregnancies with a normal cervical length (CL) and a positive fetal fibronectin (fFN), we reviewed a retrospective cohort of twin pregnancies delivered in our practice from 2005 to 2010. Patients were screened from 22 to 32 weeks with CL and fFN at ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0031-1285827
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:The aim of the article is to review the effectiveness of neonatal noninvasive high-frequency ventilation (NIHFV) in preventing endotracheal mechanical ventilation. STUDY DESIGN:Retrospective case series including all 79 instances of NIHFV use at four participating centers between July 2010 and September 2012...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1381317
更新日期:2015-02-01 00:00:00
abstract::End-stage renal disease complicates only a small percentage of pregnancies, but, of these, virtually all become anemic due to a deficiency in erythropoietin. Erythropoietin has been shown to correct anemia due to renal disease in nonpregnant patients. We report two cases of erythropoietin use during pregnancy complica...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-994392
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE: It is well established that women with a previous vaginal delivery have higher success rates in relation to vaginal birth after cesarean than those without. The aim of this study was to examine the effect of past mode of delivery on contractile parameters of human myometrium in vitro. STUDY DESIGN: Myometri...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1694980
更新日期:2021-01-01 00:00:00
abstract::Our objective was to compare the incidence of recurrent spontaneous preterm delivery (SPTD) in patients with cervical cerclage treated with weekly 17 alpha-hydroxyprogesterone caproate (17P) injections versus daily outpatient nursing surveillance (ONS) without 17P. Included in this retrospective cohort study were sing...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2008-1064935
更新日期:2008-05-01 00:00:00
abstract::Two cases of inadvertent third trimester amniocenteses occurring during attempted spinal tap and culdocentesis are presented. These hitherto undescribed occurrences stress potential complications of these invasive diagnostic procedures in the gravid woman. ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994618
更新日期:1993-11-01 00:00:00
abstract:OBJECTIVE:This study was aimed to evaluate the prevalence of sonographic markers for placenta accreta spectrum (PAS) in pregnancies at low-risk for PAS. STUDY DESIGN:Pregnant women at low-risk for PAS presenting for routine second trimester ultrasound who enrolled in the study were evaluated prospectively for sonograp...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1676488
更新日期:2019-07-01 00:00:00
abstract::Amniocentesis to guide the management of preterm pregnancies complicated by premature rupture of the membranes (PROM) has been adopted at several centers. The purpose of this study was to evaluate this practice prospectively among comparable groups of patients, which has not previously been reported. Forty-seven patie...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2007-1000031
更新日期:1984-07-01 00:00:00
abstract:OBJECTIVE:Delivery room (DR) management may play an important role in the development and prevention of lung injury. Therefore, in a cohort of low birth weight infants (LBW), we investigated the effects of two different lung recruitment maneuvers, such as positive pressure ventilation (PPV) and sustained inflation (SI)...
journal_title:American journal of perinatology
pub_type: 杂志文章,随机对照试验
doi:10.1055/s-0039-1692133
更新日期:2019-07-01 00:00:00
abstract::We assessed the pattern of levo-thyroxine (l-thyroxine) therapy in very premature newborns over a 10-year period. We analyzed the electronic database of a large private neonatal practice group (Pediatrix, Ft. Lauderdale, FL) for 23- to 32-week gestation neonates ( N = 96,813) managed during 1997 to 2006. L-thyroxine u...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0030-1253556
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:Magnesium historically has been used for treatment and/or prevention of eclampsia or preterm labor. More recently, antepartum magnesium sulfate has been suggested for prevention of cerebral palsy in preterm infants. Although adverse effects and toxicity of magnesium in pregnant women are well known, the fetal...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0032-1316440
更新日期:2012-11-01 00:00:00
abstract::An abdominal gunshot wound in pregnancy warrants prompt surgical exploration but does not mandate uterine evacuation. Despite an entry and exit bullet wound to the uterus an apparent desire for pregnancy termination, a conservative approach was adopted with primary repair of the uterus, in conjunction with surgical re...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999691
更新日期:1988-07-01 00:00:00
abstract::Our objective was to describe the change in the level of troponin I in patients who undergo a vaginal or cesarean delivery. We obtained troponin I levels on admission and 1 hour after delivery in women undergoing vaginal and cesarean deliveries. Exclusion criteria included <37 weeks' gestation, a history of cardiac di...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2004-820507
更新日期:2004-01-01 00:00:00
abstract::We present the outcome of a relatively large cohort of women with suspected placenta accreta who underwent prophylactic pelvic artery catheterization prior to cesarean section. All pregnant women with suspected placenta accreta who delivered in one tertiary center were included in this retrospective study. All patient...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0030-1247599
更新日期:2010-06-01 00:00:00
abstract::The objective of this study was to define the variables associated with vaginal birth after cesarean section (VBAC) and to develop a scoring system for the prediction of successful VBAC. We searched our computerized database for parturients with a history of one low-transverse cesarean section (CS) who were delivered ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2004-835961
更新日期:2004-11-01 00:00:00
abstract::Preeclampsia is uncommon prior to 24 weeks gestation and has been associated with partial and complete hydatidiform moles. We present an unusual case in which a patient was diagnosed with preeclampsia at 17 weeks gestation. Ultrasound findings were consistent with a partial hydatidiform mole. Within 24 hours of the on...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2006-934093
更新日期:2006-04-01 00:00:00
abstract::There is increasing concern about Chlamydia trachomatis infection during pregnancy, because of reports of increased maternal, fetal, and neonatal risks. Amniotic fluid is known to possess antibacterial activity and has recently been shown to inhibit formation of chlamydial inclusions in McCoy cell culture. To further ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999341
更新日期:1991-01-01 00:00:00