Managing rapid metabolizers of antidepressants.

abstract：:The diagnosis of anxiety disorders and major depression can be reliably made based on signs and symptoms. However there are significant limitations to the current system of classification including overlapping criteria, high comorbidity, and the issue of subthreshold syndromes. The literature on treatment response doc...

journal_title：Depression and anxiety

authors： Ninan PT,Berger J

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:To explore the anxiolytic effects of a 4-month randomized, placebo-controlled trial of exercise and antidepressant medication in patients with major depressive disorder (MDD), and to examine the potential modifying effects of anxiety in treating depressive symptoms. MATERIALS AND METHODS:In this secondary a...

journal_title：Depression and anxiety

authors： Blumenthal JA,Babyak MA,Craighead WE,Davidson J,Hinderliter A,Hoffman B,Doraiswamy PM,Sherwood A

更新日期：2020-08-12 00:00:00

abstract：:This study sought to describe clinical and demographic characteristics differentiating patients with DSM-III-R simple phobias comorbid with one or more of five DSM-III-R index anxiety disorders as compared with those with the index diagnoses alone. From 711 subjects participating in a multicenter, longitudinal, natura...

journal_title：Depression and anxiety

authors： Goisman RM,Allsworth J,Rogers MP,Warshaw MG,Goldenberg I,Vasile RG,Rodriguez-Villa F,Mallya G,Keller MB

更新日期：1998-01-01 00:00:00

abstract：:This study seeks to determine how panic disorder patients with anxiety and depression comorbidity differ from panic disorder patients without comorbidity at the time of presentation for treatment. One-hundred seventy-one panic disorder patients presenting for their initial assessment and treatment at the Payne Whitney...

journal_title：Depression and anxiety

authors： Apfeldorf WJ,Spielman LA,Cloitre M,Heckelman L,Shear MK

更新日期：2000-01-01 00:00:00

abstract：:Treatment-resistant depression (TRD) in adolescents is prevalent and impairing. We here review the definition, prevalence, clinical significance, risk factors, and management of TRD in adolescents. Risk factors associated with TRD include characteristics of depression (severity, level of hopelessness, and suicidal ide...

journal_title：Depression and anxiety

authors： Maalouf FT,Atwi M,Brent DA

更新日期：2011-11-01 00:00:00

abstract：:This study examined sex differences in the use of coping strategies and their relationship to depression and anxiety-related psychopathology. Responses on measures of coping strategies, depression, and anxiety were obtained from a carefully screened nonclinical sample (N = 107). The results demonstrated that women who...

journal_title：Depression and anxiety

authors： Kelly MM,Tyrka AR,Price LH,Carpenter LL

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Few studies have longitudinally examined predictors of posttraumatic stress disorder (PTSD) in a nationally representative sample of US veterans. We examined predictors of warzone-related PTSD over a 25-year span using data from the National Vietnam Veterans Longitudinal Study (NVVLS). METHODS:The NVVLS is ...

journal_title：Depression and anxiety

authors： Steenkamp MM,Schlenger WE,Corry N,Henn-Haase C,Qian M,Li M,Horesh D,Karstoft KI,Williams C,Ho CL,Shalev A,Kulka R,Marmar C

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Little is known about the association between trauma exposure and suicidal ideation across racial/ethnic groups. Our study aim was to determine the association between trauma exposure and suicidal ideation in a nationally representative ethnically diverse sample of adults. METHODS:This study included 14,866...

journal_title：Depression and anxiety

authors： Beristianos MH,Maguen S,Neylan TC,Byers AL

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The clinical presentation of panic disorder (PD) is known to be highly heterogeneous, complicating research on its etiology, neurobiological pathways, and treatment. None of the attempts to identify PD subtypes have been independently reproduced, rendering the current literature inconclusive. METHODS:Using ...

journal_title：Depression and anxiety

authors： Pattyn T,Van Den Eede F,Lamers F,Veltman D,Sabbe BG,Penninx BW

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Metacognitive therapy (MCT) is a relatively new approach to treating mental disorders. The aim of the current meta-analysis was to examine the efficacy of MCT in patients with mental disorders. METHOD:A comprehensive literature search revealed 16 published as well as unpublished studies on the efficacy of M...

journal_title：Depression and anxiety

authors： Normann N,van Emmerik AA,Morina N

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Transdiagnostic cognitive-behavioral treatments for anxiety disorders have been gaining increased attention and empirical study in recent years. Despite this, research on transdiagnostic anxiety treatments has, to date, relied on open trials, or comparisons to waitlist conditions, published benchmarks, or re...

journal_title：Depression and anxiety

authors： Norton PJ,Barrera TL

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Although trauma-focused cognitive behavioral therapy (TF-CBT) is the frontline treatment for posttraumatic stress disorder (PTSD), at least one-third of patients are treatment nonresponders. This study aimed to identify neural markers of treatment response, specifically the prediction of remission of specifi...

journal_title：Depression and anxiety

authors： Bryant RA,Erlinger M,Felmingham K,Malhi GS,O'Donnell ML,Williams LM,Korgaonkar MS

更新日期：2020-10-01 00:00:00

abstract：:Given the high rates of maladjustment among children of depressed mothers, parenting is likely to cause significant life stress in this population, potentially worsening the course of mothers' depression. The present study is a comparison of severe life stress in 38 mothers and 62 non-mothers receiving treatment for r...

journal_title：Depression and anxiety

authors： Feske U,Shear MK,Anderson B,Cyranowski J,Strassburger M,Matty M,Luther J,Frank E

更新日期：2001-01-01 00:00:00

abstract：:Research on the effects of childhood trauma has been limited by the lack of a comprehensive, reliable, and valid instrument that assesses the occurrence of early traumatic experiences. This paper presents the development and preliminary psychometric properties of an instrument, the Early Trauma Inventory (ETI), for th...

journal_title：Depression and anxiety

authors： Bremner JD,Vermetten E,Mazure CM

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:The significance of the timing and chronicity of childhood adversity for depression outcomes later in life is unclear. Identifying trajectories of adversity throughout childhood would allow classification of children according to the accumulation, timing, and persistence of adversity, and may provide unique ...

journal_title：Depression and anxiety

authors： Tracy M,Salo M,Slopen N,Udo T,Appleton AA

更新日期：2019-07-01 00:00:00

abstract：:Placebo-controlled trials have evaluated the efficacy of several medications in the treatment of social anxiety disorder but information regarding their relative efficacy is lacking. We compared the efficacy of medications systematically studied for the treatment of social anxiety disorder using meta-analytic techniqu...

journal_title：Depression and anxiety

authors： Blanco C,Schneier FR,Schmidt A,Blanco-Jerez CR,Marshall RD,Sánchez-Lacay A,Liebowitz MR

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Obsessive-compulsive disorder (OCD) is a heterogeneous condition, which can be expressed as various potentially overlapping symptom dimensions. In clinical samples, some of these dimensions are associated with increased familial risk for OCD and appear to be familial (intercorrelated within pairs of affected...

journal_title：Depression and anxiety

authors： Taberner J,Fullana MA,Caseras X,Pertusa A,Bados A,van den Bree M,Torrubia R,Mataix-Cols D

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Neural activity is increasingly used in addition to behavioral measures to study anxiety and attentional biases toward threatening stimuli. Event-related potentials (ERPs) might be particularly useful because of their excellent temporal resolution. In particular, the late positive potential (LPP) reflects in...

journal_title：Depression and anxiety

authors： MacNamara A,Hajcak G

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Generalized anxiety disorder (GAD) is a common and sometimes disabling condition often associated with stressful life events that involve significant loss or danger. The disorder appears moderately heritable. Polymorphisms in the RGS2 (regulator of G-protein signaling 2) gene were recently associated with an...

journal_title：Depression and anxiety

authors： Koenen KC,Amstadter AB,Ruggiero KJ,Acierno R,Galea S,Kilpatrick DG,Gelernter J

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Major depressive disorder (MDD) has been associated with changes in mean telomere length and mitochondrial DNA (mtDNA) copy number. This study investigates if clinical features of MDD differentially impact these molecular markers. METHODS:Data from a large, clinically ascertained sample of Han Chinese women...

journal_title：Depression and anxiety

authors： Edwards AC,Aggen SH,Cai N,Bigdeli TB,Peterson RE,Docherty AR,Webb BT,Bacanu SA,Flint J,Kendler KS

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:The role of the neuropeptide oxytocin (OT) in Borderline Personality Disorder (BPD) is poorly understood. It is particularly unknown how early experiences with caregivers moderate the action of OT in BPD. Here, we examined the association of plasma OT levels in BPD patients with the experience of c...

journal_title：Depression and anxiety

authors： Ebert A,Edel MA,Gilbert P,Brüne M

更新日期：2018-01-01 00:00:00

abstract：:Increasing attention has been paid to the role of inflammation in a host of illnesses including neuropsychiatric disorders such as depression and anxiety. Activation of the inflammatory response leads to release of inflammatory cytokines and mobilization of immune cells both of which have been shown to access the brai...

journal_title：Depression and anxiety

authors： Miller AH,Haroon E,Raison CL,Felger JC

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Smoking in patients with bipolar disorder is known to be related to suicidality. This link has not been investigated, however, in community-based samples. The aim of this study is to delineate the sociodemographic and clinical characteristics of bipolar smokers and examine the relationship between these char...

journal_title：Depression and anxiety

authors： Baek JH,Eisner LR,Nierenberg AA

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:To determine the factors, which are associated with suicidal ideation and ideas of self-harm in patients with congestive heart failure (CHF). METHODS:We examined 294 patients with documented CHF, New York Heart Association (NYHA) functional class II-IV, in a cross sectional study at three cardiac outpatient ...

journal_title：Depression and anxiety

authors： Lossnitzer N,Müller-Tasch T,Löwe B,Zugck C,Nelles M,Remppis A,Haass M,Rauch B,Jünger J,Herzog W,Wild B

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:A history of past major depressive episodes (MDEs) is known to be a risk factor for future MDEs. Additional information about the relationship between past and future episodes would be useful in clinical practice, it is therefore important to fully understand the epidemiology of major depression. We asked wh...

journal_title：Depression and anxiety

authors： Bulloch A,Williams J,Lavorato D,Patten S

更新日期：2014-01-01 00:00:00

abstract：:There are well-established sex differences in the prevalence of certain mental disorders. Work in animal models has provided us with an emerging understanding of the role that epigenetic factors play in establishing sex differences in the brain during development. Similarly, work in animal models, and a more limited b...

journal_title：Depression and anxiety

authors： Uddin M,Sipahi L,Li J,Koenen KC

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The present trial was designed to assess the efficacy and safety of escitalopram prescribed to patients seeking treatment of major depressive disorder (MDD) in a Canadian primary-care setting. METHODS:Investigators (mainly primary-care physicians) enrolled patients with MDD from their daily practice. Patien...

journal_title：Depression and anxiety

authors： Chokka P,Legault M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Psychosocial factors, including religious coping, consistently have been implicated in the expression of anxiety disorders. This study sought to investigate the relationship between religious coping on anxiety symptoms among a nonclinical sample of African American and European American young adults. METHOD...

journal_title：Depression and anxiety

authors： Chapman LK,Steger MF

更新日期：2010-03-01 00:00:00

abstract：:The growing recognition and occurrence of traumatic exposure in the general population has given increased salience to the need to understand the concept of resilience. More than just the "flip side" of a risk factor, the notion of resilience encompasses psychological and biological characteristics, intrinsic to an in...

journal_title：Depression and anxiety

authors： Hoge EA,Austin ED,Pollack MH

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The impact of the May 2008 Wenchuan earthquake, measuring a massive 8.0 on the surface wave magnitude scale, on public health in China has been significant and multifaceted. In light of extant data on prevalence and risk factors for posttraumatic stress disorder (PTSD) after other natural diasters, we collec...

journal_title：Depression and anxiety

authors： Kun P,Han S,Chen X,Yao L

更新日期：2009-01-01 00:00:00