Fetal DNA in maternal plasma.

abstract：:Autophagy is a phylogenetically conserved process that plays a critical role in the degradation of oxidatively damaged proteins and organelle turnover. The role of oxidative stress and apoptosis in methamphetamine (METH)-induced neurotoxicity is well known; however, the potential contribution of autophagy to METH-indu...

journal_title：Annals of the New York Academy of Sciences

authors： Kanthasamy A,Anantharam V,Ali SF,Kanthasamy AG

更新日期：2006-08-01 00:00:00

abstract：:Perception, preference, and selection are all objectively measurable performances that discriminate between different levels of entities such as the sugar, thickener, or protein in a food. A rating or an intake may not be controlled by the word that the experimenter or the subject uses to describe it: "protein"-orient...

journal_title：Annals of the New York Academy of Sciences

authors： Booth DA,Conner MT,Gibson EL

更新日期：1989-01-01 00:00:00

abstract：:Without landmarks, navigation is based on information about self-velocity, which is transformed to position or orientation by a process called path integration. Simple path integration tasks, such as reaching a previously seen goal by blindfolded locomotion, were often considered to be automatic and not influenced by ...

journal_title：Annals of the New York Academy of Sciences

authors： Glasauer S,Stein A,Günther AL,Flanagin VL,Jahn K,Brandt T

更新日期：2009-05-01 00:00:00

abstract：:Indirect evidence, including neuroprotection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-neurotoxicity by nitric oxide synthase (NOS) inhibitors and resistance of transgenic animals deficient in NOS, is controversial. We have reviewed evidence in favor of oxidative stress during the development of MPTP...

journal_title：Annals of the New York Academy of Sciences

authors： Mohanakumar KP,Thomas B,Sharma SM,Muralikrishnan D,Chowdhury R,Chiueh CC

更新日期：2002-05-01 00:00:00

abstract：:In the present article we assessed exposure to polycyclic aromatic hydrocarbons (PAHs) in Italian asphalt workers (AW, n = 100), exposed to bitumen fumes and diesel exhausts, and in roadside construction workers (CW, n = 47), exposed to diesel exhausts, by means of environmental and biological monitoring. 1-hydroxypyr...

journal_title：Annals of the New York Academy of Sciences

authors： Campo L,Buratti M,Fustinoni S,Cirla PE,Martinotti I,Longhi O,Cavallo D,Foà V

更新日期：2006-09-01 00:00:00

abstract：:Experiments with enzymes in situ that are dependent on ascorbic acid for maximum activity will provide critical information about ascorbic acid requirements. Our work with chromaffin tissue as a model system eventually will result in the determination of two dose-response curves for norepinephrine biosynthesis, repres...

journal_title：Annals of the New York Academy of Sciences

authors： Levine M,Hartzell W

更新日期：1987-01-01 00:00:00

abstract：:Exposure of quail eggs 4 hr per day during the first 5 incubation days at 2450 MHz and in an exposure field of 30 mW/cm-2 and at an absorbed power of 14 mW/g does not cause any great change in body weight, observed gross malformations, rbc, wbc, hematocrit, hemoglobin, or differential wbc percentages. If small differe...

journal_title：Annals of the New York Academy of Sciences

authors： McRee DI,Hamrick PE,Zinkl J,Thaxton P,Parkhurst CR

更新日期：1975-02-28 00:00:00

abstract：:Vaccinia virus encodes secretory proteins termed virokines. One of the major virokines encoded by the N1L open reading frame is the 13.8 kDa protein. A recombinant virus, termed vGK5, lacking this protein when injected intracranially into mice, has one of the highest levels of in vivo attenuation achieved by deletion ...

journal_title：Annals of the New York Academy of Sciences

authors： Billings B,Smith SA,Zhang Z,Lahiri DK,Kotwal GJ

更新日期：2004-12-01 00:00:00

abstract：:Three distinct anion exchangers are described that directly or indirectly mediate Cl- transport across the luminal membrane of the proximal tubule cell. Studies on the intact proximal tubule indicate that the Cl(-)-formate exchanger is a major mechanism for Cl- transport under physiologic conditions. As just discussed...

journal_title：Annals of the New York Academy of Sciences

authors： Aronson PS,Kuo SM

更新日期：1989-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is an idiopathic autoimmune disease characterized by impaired T lymphocyte immune effector functions. We have identified a disorder of signal transduction in SLE T cells involving the cyclic AMP/protein kinase A (cAMP/PKA) pathway. Cyclic AMP-stimulated PKA-catalyzed protein phosphor...

journal_title：Annals of the New York Academy of Sciences

authors： Kammer GM

更新日期：2002-06-01 00:00:00

abstract：:Anticardiolipin antibodies (aCLAs) and antibodies to oxidized-low density lipoproteins (oxLDL) are associated with two distinct diseases: the antiphospholipid syndrome and atherosclerosis. Because both diseases may be apparent in patients with systemic lupus erythematosus (SLE), it is important to establish the relati...

journal_title：Annals of the New York Academy of Sciences

authors： Damoiseaux J,Jeyasekharan AD,Theunissen R,Tervaert JW

更新日期：2005-06-01 00:00:00

abstract：:Previous research on development of the Xenopus olfactory bulb from our laboratory has shown that mitral cells begin to differentiate after olfactory axons make contact with the olfactory bulb, and the number of olfactory axons is correlated with the number of mitral cells throughout development. In embryos, removal o...

journal_title：Annals of the New York Academy of Sciences

authors： Burd GD,Sein V

更新日期：1998-11-30 00:00:00

abstract：:Stabilization of images on the fovea during either fore/aft translation of a subject or fore/aft movement of a visual target in front of a stationary observer imposes complex geometrical requirements that depend upon the eccentricity of the object of interest with respect to the eyes. Each eye needs to be rotated inde...

journal_title：Annals of the New York Academy of Sciences

authors： Ramat S,Zee DS

更新日期：2005-04-01 00:00:00

abstract：:The membrane domain of the Na(+)/Ca(2+) exchanger (NCX) contains two conserved internal repeat sequences, designated the alpha-1 and alpha-2 repeats. We have studied the topological disposition of residues in the alpha repeats and a neighboring region by substituted cysteine accessibility scanning as well as the funct...

journal_title：Annals of the New York Academy of Sciences

authors： Shigekawa M,Iwamoto T,Uehara A,Kita S

更新日期：2002-11-01 00:00:00

abstract：:Alexithymia has been associated with both posttraumatic stress disorder and neuroendocrine responses to stress. This study examined the relationship of alexithymia to salivary cortisol and 3-methoxy-4-hydroxy-phenylglycol (MHPG) in a sample of police academy recruits exposed to a video stress challenge. Alexithymia sc...

journal_title：Annals of the New York Academy of Sciences

authors： McCaslin SE,Inslicht SS,Neylan TC,Metzler TJ,Otte C,Lenoci M,Henn-Haase C,Best S,Yehuda R,Marmar CR

更新日期：2006-07-01 00:00:00

abstract：:Several orphan G-protein-coupled receptors (GPCRs), LGR7 and LGR8, GPCR135 and GPCR142, were recently identified as putative, native receptors for different relaxin-family peptides, and their cell signaling mechanisms were elucidated in stably transfected cell lines. Anatomic studies have demonstrated that discrete po...

journal_title：Annals of the New York Academy of Sciences

authors： Ortinau S,Lin F,Wade JD,Tregear GW,Bathgate RA,Gundlach AL

更新日期：2005-05-01 00:00:00

abstract：:The apolipoprotein E (APOE) gene causes a major risk factor for the development of Alzheimer's disease (AD). To study the transcription control of the mouse (m) APOE gene, we first tested the promoter activity of a 721-base-pair (bp) 5'-flanking region, which is located 771 bp upstream from the translation initiation ...

journal_title：Annals of the New York Academy of Sciences

authors： Lahiri DK,Alley GM,Ge YW,Du Y

更新日期：2002-11-01 00:00:00

abstract：:Anti-inflammatory efficacy of the fermented wheat germ extract (FWGE, Avemar) in the rat adjuvant arthritis (AA) model was examined. To Wistar rats with AA, different doses of FWGE and anti-inflammatory drugs (indomethacin, dexamethasone) as monotherapies were administered and FWGE and either diclofenac or dexamethaso...

journal_title：Annals of the New York Academy of Sciences

authors： Telekes A,Resetar A,Balint G,Blazso G,Falkay G,Lapis K,Raso E,Szende B,Ehrenfeld M,Shoenfeld Y,Hidvegi M

更新日期：2007-09-01 00:00:00

abstract：:The present study examined the effects of psychological stress on performance quality, autonomic responses, and upper extremity muscle activity in skilled pianists through comparisons between stressful (competition) and nonstressful (rehearsal) conditions. We observed increased levels of subjective anxiety, autonomic ...

journal_title：Annals of the New York Academy of Sciences

authors： Yoshie M,Kudo K,Ohtsuki T

更新日期：2009-07-01 00:00:00

abstract：:Using the Diagrammatic Cell Language trade mark, Gene Network Sciences (GNS) has created a network model of interconnected signal transduction pathways and gene expression networks that control human cell proliferation and apoptosis. It includes receptor activation and mitogenic signaling, initiation of cell cycle, an...

journal_title：Annals of the New York Academy of Sciences

authors： Christopher R,Dhiman A,Fox J,Gendelman R,Haberitcher T,Kagle D,Spizz G,Khalil IG,Hill C

更新日期：2004-05-01 00:00:00

abstract：:Mitochondria display considerable structural diversity particularly in terms of the folding of the energy-transducing inner membrane. The hypothesis is forwarded that the topology of the mitochondrial inner membrane is not random but rather is a regulated cell parameter. Its effects on internal diffusion of metabolite...

journal_title：Annals of the New York Academy of Sciences

authors： Mannella CA

更新日期：2008-12-01 00:00:00

abstract：:The present study was designed to immunochemically identify a coronin-like protein in Babesia bovis, B. bigemina, B. divergens, and B. canis. A 2-kbp cDNA insert of B. bovis carried by plasmid BvN9 was sequenced by the dideoxichain-termination method on both strands. The cDNA insert contained a 1719-bp long open readi...

journal_title：Annals of the New York Academy of Sciences

authors： Figueroa JV,Precigout E,Carcy B,Gorenflot A

更新日期：2004-10-01 00:00:00

abstract：:The present paper reviews the major modes of action of estrogen on the molecular, cellular, tissue, and neurobehavioral levels of mammalian physiology, with an emphasis on the brain as an estrogen target tissue. We draw a distinction between receptor- and nonreceptor-mediated actions, as well as delineate the range of...

journal_title：Annals of the New York Academy of Sciences

authors： Scallet AC

更新日期：1999-01-01 00:00:00

abstract：:In humans any effects of dietary saturated fats or omega-6 polyunsaturates on blood pressure appear to be mediated by changes in caloric intake and long-term weight changes. In contrast, omega-3 fatty acids have a mild antihypertensive effect which is seen most clearly in untreated subjects with higher blood pressures...

journal_title：Annals of the New York Academy of Sciences

authors： Beilin LJ

更新日期：1993-06-14 00:00:00

abstract：:The muscular dystrophies, which cause progressive weakening of the skeletal muscles, are frequently associated with cardiomyopathy. In fact, the leading cause of mortality in patients with Duchenne muscular dystrophy, the most common and most severe type of muscular dystrophy, is heart failure due to cardiomyopathy. T...

journal_title：Annals of the New York Academy of Sciences

authors： Kuno A,Tanno M,Horio Y

更新日期：2015-08-01 00:00:00

abstract：:A short review of current concepts concerning the origin and kinetics of monocytes and macrophages is given, and the humoral regulation of monocyte production by FIM, a factor synthesized and secreted by macrophages, is discussed. Genetic control of the responsiveness of monocyte precursors to FIM and that of the phag...

journal_title：Annals of the New York Academy of Sciences

authors： van Furth R,Sluiter W,van Dissel JT

更新日期：1986-01-01 00:00:00

abstract：:More than 10% of postmenopausal women in the United States receive thyroid hormone replacement therapy and up to 20% of these women are over-replaced inducing subclinical hyperthyroidism. Because hyperthyroidism and post menopausal osteoporosis overlap in women of advancing age, it is urgent to understand the effect o...

journal_title：Annals of the New York Academy of Sciences

authors： Abe E,Sun L,Mechanick J,Iqbal J,Yamoah K,Baliram R,Arabi A,Moonga BS,Davies TF,Zaidi M

更新日期：2007-11-01 00:00:00

abstract：:The finding of an association between the epsilon 4 allele of the APOE locus and the early expression of late-onset Alzheimer's disease (AD) is robust. However, the estimates of the proportion of AD cases carrying one or more copies of the epsilon 4 allele vary dramatically between studies (highest estimates being 180...

journal_title：Annals of the New York Academy of Sciences

authors： Mullan M,Scibelli P,Duara R,Fallin D,Gold M,Schinka J,Hoyne J,Osborne A,Sevush S,Crawford F

更新日期：1996-12-16 00:00:00

abstract：:The resolution of antibiotic-ribosomal subunit complexes and antibacterial-protein complexes at the atomic level has provided new insights into modifications of clinically relevant antimicrobials and provided new classes that target the protein cellular apparatus. New chemistry platforms that use fragment-based drug d...

journal_title：Annals of the New York Academy of Sciences

authors： Sutcliffe JA

更新日期：2011-12-01 00:00:00

abstract：:Malignancies have developed several strategies to evade immune surveillance. We have investigated pancreatic cancer cell lines and pancreatic cancer surgical specimens to evaluate possibilities of tumor escape in the Fas system, and local immune suppression. Despite Fas expression the majority of cell lines was resist...

journal_title：Annals of the New York Academy of Sciences

authors： Ungefroren H,Voss M,Bernstorff WV,Schmid A,Kremer B,Kalthoff H

更新日期：1999-06-30 00:00:00