Binding motifs of CBP2 a potential cell surface target for carcinoma cells.

abstract：:Cervical cancer (CC) is one of the most common cancers among females, and it is most notable in developing countries. The exact etiology of CC is poorly understood; but, smoking, oral contraceptives, immunosuppression, and infection with human papillomavirus (HPV) may increase the risk of CC. There is also an associat...

journal_title：Journal of cellular biochemistry

authors： Ebrahimi S,Soltani A,Hashemy SI

更新日期：2018-11-13 00:00:00

abstract：:HepG2 is an immortalized human hepatoma cell line that has been used for research into bioartificial liver systems. However, a low level of ammonia detoxification is its biggest drawback. In this work, a recombinant HepG2 cell line with stable overexpression of human arginase I (hArgI) and human ornithine transcarbamy...

journal_title：Journal of cellular biochemistry

authors： Tang N,Wang Y,Wang X,Zhou L,Zhang F,Li X,Chen Y

更新日期：2012-02-01 00:00:00

abstract：:We have examined the effect of calcium-dependent adhesion, mediated by N-cadherin, on cell signaling during chondrogenesis of multipotential embryonic mouse C3H10T1/2 cells. The activity of chondrogenic genes, type II collagen, aggrecan, and Sox9 were examined in monolayer (non-chondrogenic), and micromass (chondrogen...

journal_title：Journal of cellular biochemistry

authors： Modarresi R,Lafond T,Roman-Blas JA,Danielson KG,Tuan RS,Seghatoleslami MR

更新日期：2005-05-01 00:00:00

abstract：:The 4-quinolone antibiotics nalidixic acid and ciprofloxacin are potent inhibitors of the bacterial type II topoisomerase DNA gyrase. Treatment of mouse L1210 leukemia cells with these drugs resulted in a delayed inhibition of cell proliferation. Prior to inhibition of cell proliferation, there was a time-dependent de...

journal_title：Journal of cellular biochemistry

authors： Lawrence JW,Darkin-Rattray S,Xie F,Neims AH,Rowe TC

更新日期：1993-02-01 00:00:00

abstract：:Survivin is a member of the inhibitor of apoptosis (IAP) gene family, containing a single baculovirus IAP repeat (BIR) and no RING finger, that is expressed in many human cancers. Although it has been proposed to be involved in mitotic and cytokinetic processes, its functional subcellular distribution in the cytoplasm...

journal_title：Journal of cellular biochemistry

authors： Jiang X,Wilford C,Duensing S,Munger K,Jones G,Jones D

更新日期：2001-08-01 00:00:00

abstract：:Rearrangement of cell-cell adhesion is a critical event in embryonic development and tissue formation. We investigated the regulatory function of E-cadherin, a key adhesion protein, in the developmental process by using E-cadherin/IgG Fc fusion protein as an adhesion matrix in cell culture. F9 embryonal carcinoma cell...

journal_title：Journal of cellular biochemistry

authors： Nagaoka M,Ise H,Harada I,Koshimizu U,Maruyama A,Akaike T

更新日期：2008-01-01 00:00:00

abstract：:Pyruvate kinase M2 (M2-PK) controls the rate-limiting step at the end of the glycolytic pathway in normal proliferating and tumor cells. Other functions of M2-PK in addition to its role in glycolysis are little understood. The aim of this study was to identify new cellular interaction partners of M2-PK in order to dis...

journal_title：Journal of cellular biochemistry

authors： Spoden GA,Morandell D,Ehehalt D,Fiedler M,Jansen-Dürr P,Hermann M,Zwerschke W

更新日期：2009-05-15 00:00:00

abstract：:Previous studies from this and other laboratories have shown that variants of tumor cell lines can be selected for resistance to the lytic action of natural killer (NK) cells. One of these (K562-Clone I), when made resistant to the toxic effects of Concanavalin A (Con A-R1), regained its sensitivity to NK. Comparing t...

journal_title：Journal of cellular biochemistry

authors： Bernier LG,Sullivan AK

更新日期：1988-06-01 00:00:00

abstract：:Osteosarcoma is the most common malignant bone tumor in children and adolescents with high rate of incidence, high frequency of recurrence, and high degree of metastasis. This study aimed to investigate the effects of long noncoding RNA antisense ncRNA in the abundant in neuroepithelium area (ANA)/B-cell translocation...

journal_title：Journal of cellular biochemistry

authors： Zhao J,Zhang C,Gao Z,Wu H,Gu R,Jiang R

更新日期：2018-08-01 00:00:00

abstract：:Connexin43 (Cx43) is a ubiquitously expressed member of the gap junction protein family that mediates gap junction intercellular communication (GJIC) by allowing exchange of cytosolic materials. Previous studies have used Cx43 truncated at the cytoplasmic tail (C-tail) to demonstrate that the C-tail is essential to re...

journal_title：Journal of cellular biochemistry

authors： Crespin S,Bechberger J,Mesnil M,Naus CC,Sin WC

更新日期：2010-06-01 00:00:00

abstract：:By Western blot and immunostaining we proved that polyvinylpyrrolidone (PVP)-wrapped fullerene molecules (PVP-fullerene) could combine the 8- and 53-kb proteins which localize in the membrane of human skin keratinocytes HaCaT. Only fullerene molecules are able to cross the lipid membrane and conjugate 53-kb proteins i...

journal_title：Journal of cellular biochemistry

authors： Xiao L,Aoshima H,Saitoh Y,Miwa N

更新日期：2010-11-01 00:00:00

abstract：:Metastatic variant cell lines of the murine RAW117 large cell lymphoma were used to study the cell surface components involved in syngeneic tumor cell/microvessel endothelial cell interactions. Poorly liver-metastatic parental RAW117-P cell line adhered to murine hepatic sinusoidal endothelial cell monolayers at signi...

journal_title：Journal of cellular biochemistry

authors： Tressler RJ,Nicolson GL

更新日期：1992-02-01 00:00:00

abstract：:We have constructed a phage lambda library of liver DNA fragments from West African patient who died of liver failure due to advanced hepatocellular carcinoma. Four hepatitis B virus (HBV) DNA-carrying recombinants have been isolated, one clone (lambda IA22) being analyzed in greatest detail. It contains approximately...

journal_title：Journal of cellular biochemistry

authors： Dejean A,Carloni G,Bréchot C,Tiollais P,Wain-Hobson S

更新日期：1982-01-01 00:00:00

abstract：:Osteogenic differentiation refers to the process of bone formation and remodeling, which is controlled by complex molecular mechanisms. Activin A receptor type I (ACVR1) is reported to be associated with osteogenic differentiation. However, the underlying molecular mechanism remains elusive. Therefore, this study eval...

journal_title：Journal of cellular biochemistry

authors： Wang Y,Sun JC,Wang HB,Xu XM,Kong QJ,Wang YJ,Zheng B,Shi GD,Shi JG

更新日期：2018-12-16 00:00:00

abstract：:Stimulation of osteoblast survival signals may be an important mechanism of regulating bone anabolism. Protein kinase B (PKB/Akt), a serine-threonine protein kinase, is a critical regulator of normal cell growth, cell cycle progression, and cell survival. In this study we have investigated the signaling pathways activ...

journal_title：Journal of cellular biochemistry

authors： Chaudhary LR,Hruska KA

更新日期：2001-03-26 00:00:00

abstract：:The activated c-Ha-rasVal12 oncogene is often involved in the genesis of human malignancies. We show here that in c-Ha-rasVal12 oncogene-transformed mouse NIH 3T3 fibroblasts the copy number and expression level of the mutant ras oncogene correlates with the degree of chromatin decondensation, as assessed by micrococc...

journal_title：Journal of cellular biochemistry

authors： Laitinen J,Sistonen L,Alitalo K,Hölttä E

更新日期：1995-01-01 00:00:00

abstract：:Integrins are heterodimeric transmembrane cellular receptors that link the cell to its underlying substratum. Alterations in integrin expression and signaling have been implicated in many aspects of tumorigenesis and metastasis including cell survival, migration, and invasion. In prostate cancer, the progression from ...

journal_title：Journal of cellular biochemistry

authors： Slack-Davis JK,Parsons JT

更新日期：2004-01-01 00:00:00

abstract：:The identification and purification of murine multipotent mesenchymal stem cells (MSCs) have been difficult due to their low frequency, the presence of contaminating cell types and lack of unambiguous markers. Using a magnetic micro-beads negative selection technique to remove hematopoietic cells from mouse bone marro...

journal_title：Journal of cellular biochemistry

authors： McKenzie KP,Mayer DC,Aubin JE

更新日期：2013-05-01 00:00:00

abstract：:Fibroblasts play a major role in processes such as wound repair, scarring, and fibrosis. Differentiation into myofibroblasts, characterized by upregulation of smooth muscle alpha-actin (smalpha) in response to profibrotic agents such as TGFbeta is believed to be an important step in fibrosis. Therefore, elucidating me...

journal_title：Journal of cellular biochemistry

authors： Sousa AM,Liu T,Guevara O,Stevens J,Fanburg BL,Gaestel M,Toksoz D,Kayyali US

更新日期：2007-04-15 00:00:00

abstract：:Cervical cancer is among the most common type of cancers in women and is associated with human papillomavirus (HPV) infection. Genital warts are also reported to be linked with HPV infection types 11 and 6. In turn, clinical characteristics and morphological features of warts may be useful in the prediction of prognos...

journal_title：Journal of cellular biochemistry

authors： Hasanzadeh M,Rejali M,Mehramiz M,Akbari M,Mousavi Seresht L,Yazdandoost Y,Farokhi S,Mahdian Z,Maleki F,Emamdadi-Aliabad Z,Jalilvand N,Khorrami S,Fadaei Z,Movahedi M,Hosseini Z,Razmi F,Takamoli T,Ferns GA,Avan A

更新日期：2019-08-01 00:00:00

abstract：:NMR spectroscopy is able to detect subtle changes to the surface chemistry of cells. We have previously shown that high-resolution 1H NMR methods can identify tumor cells with the capacity to metastasize, and we now report that the long T2 relaxation value (500-800 ms) observed in metastatic rat mammary adenocarcinoma...

journal_title：Journal of cellular biochemistry

authors： Wright LC,May GL,Gregory P,Dyne M,Holmes KT,Williams PG,Mountford CE

更新日期：1988-05-01 00:00:00

abstract：:In this experiment, the cross-talk betweenNotch and the NF-κB signaling pathway was examined to reveal the mechanism of slowing down the type II collagen (ColII) and aggrecan degeneration affected by inflammatory cytokines. The expression levels of ColII and aggrecan in the intervertebral disc were observed through im...

journal_title：Journal of cellular biochemistry

authors： Huang Y,Mei W,Chen J,Jiang T,Zhou Z,Yin G,Fan J

更新日期：2018-10-26 00:00:00

abstract：:The objective of this study was to test the hypothesis that extracellular matrix (ECM) would alter the endoplasmic reticulum (ER) stress response of chondrocytes. Chondrocytes were isolated from calf knees and maintained in monolayer culture or suspended in collagen I to form spot cultures (SCs). Our laboratory has sh...

journal_title：Journal of cellular biochemistry

authors： Nugent AE,McBurney DL,Horton WE Jr

更新日期：2011-04-01 00:00:00

abstract：:In previous publications, we showed that extracellular glycosaminoglycans reduced the membrane potential, caused cell blebbing and swelling and decreased the intracellular pH independently of cell surface receptors. These phenomena were explained by Donnan effects. The effects were so large that they could not be attr...

journal_title：Journal of cellular biochemistry

authors： Hagenfeld D,Kathagen N,Prehm P

更新日期：2014-07-01 00:00:00

abstract：:Bruton's tyrosine kinase (Btk) plays a crucial role in the maturation and differentiation of B-lymphocytes and immunoglobulin synthesis. Recently Btk has been described to be present in significant amount in human platelets. To investigate the regulation of this kinase in the platelets we studied its subcellular redis...

journal_title：Journal of cellular biochemistry

authors： Mukhopadhyay S,Ramars AS,Dash D

更新日期：2001-01-01 00:00:00

abstract：:Using computer stress-induced duplex destabilization (SIDD) analysis and binding experiments, we identified a S/MAR element (-599/-200 bp) (Hp-S/MAR) adjacent to the cis-element (-165/-56 bp) in the rat haptoglobin gene. We examined its functional interactions with the lamins and lamin-associated proteins in the basal...

journal_title：Journal of cellular biochemistry

authors： Vidaković M,Dinić S,Grdović N,Mihailović M,Uskoković A,Quesada P,Poznanović G

更新日期：2009-08-15 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) may arise from potentially malignant oral lesions. All-trans retinoic acid (atRA), which plays a role in cell growth and differentiation, has been studied as a possible chemotherapeutic agent in the prevention of this progression. While the mechanism by which atRA suppresses cell gr...

journal_title：Journal of cellular biochemistry

authors： Acquafreda T,Nunes FD,Soprano DR,Soprano KJ

更新日期：2010-12-15 00:00:00

abstract：:We report here that the antiestrogen tamoxifen (TAM) induces cell death in human breast cancer cell line MCF-7. We assessed the type of cell death induced by TAM in this breast cancer cell line on the basis of morphological and biochemical characteristics. Dying cells showed morphological characteristics of apoptosis,...

journal_title：Journal of cellular biochemistry

authors： Chen H,Tritton TR,Kenny N,Absher M,Chiu JF

更新日期：1996-04-01 00:00:00

abstract：:Several molecules extracted from natural products exhibit different biological activities, such as ion channel modulation, activation of signaling pathways, and anti-inflammatory or antitumor activity. In this study, we tested the antitumor ability of natural compounds extracted from the Raputia praetermissa plant. Am...

journal_title：Journal of cellular biochemistry

authors： Vital WD,Torquato HFV,Jesus LOP,Judice WAS,Silva MFDGFD,Rodrigues T,Justo GZ,Veiga TAM,Paredes-Gamero EJ

更新日期：2019-06-01 00:00:00

abstract：:Escherichia coli is frequently exploited for genetic manipulations and heterologous gene expression studies. We have evaluated the metabolic profile of E. coli strain BL21 (DE3) RIL CodonPlus after genetic modifications and subjecting to the production of recombinant protein. Three genetically variable E. coli cell ty...

journal_title：Journal of cellular biochemistry

authors： Nadeem MS,Razeeth M,Choudhry HMZ,Anwar F,Zamzami MA,Murtaza BN,Al-Abbasi FAM,Khan MI,Shakoori AR

更新日期：2020-01-01 00:00:00