Downregulation of adenosine and P2X receptor-mediated cardiovascular responses in heart failure rats.

abstract：:The purpose of this study was to test the hypothesis of a causal relationship between high insulin levels and the development of benign prostatic hyperplasia (BPH) and to determine the clinical, anthropometric, metabolic and insulin profile in men with fast-growing BPH compared with men with slow-growing BPH. The pres...

journal_title：Blood pressure

authors： Hammarsten J,Högstedt B

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Orthostatic hypotension (OH) is common amongst the older population and is associated with morbidity and mortality. We sought to investigate predictors of OH to assist the clinician in identifying patients at risk. METHODS AND RESULTS:Database of 2696 patients attending a transient ischaemic attack (TIA) cl...

journal_title：Blood pressure

authors： de la Iglesia B,Ong AC,Potter JF,Metcalf AK,Myint PK

更新日期：2013-04-01 00:00:00

abstract：:The reduction in blood pressure seen with the use of beta-blocking drugs was an unexpected finding. Initially there was resistance to their use as the reduction of cardiac output and increase in peripheral resistance from beta-blockade was considered an undesirable pharmacological action for a drug in the treatment of...

journal_title：Blood pressure

authors： Prichard BN,Cruickshank JM,Graham BR

更新日期：2001-01-01 00:00:00

abstract：:The effectiveness of hypertension treatment remains low in many developed countries. The aim of our study was to evaluate the treatment effectiveness in hypertensives treated by general practitioners (GPs) in Poland. Twenty thousand three hundred and five hypertensive patients (mean age 60.1 +/- 12.0 years, 9918 women...

journal_title：Blood pressure

authors： Grzybowski A,Bellwon J,Gruchała M,Stolarczyk L,Popaszkiewicz J,Sobiczewski W,Rynkiewicz A

更新日期：2003-01-01 00:00:00

abstract：:In order to study the contribution of the nitric oxide (NO)-pathway to cholinergic vasodilatation in the resistance vessels of the human forearm, we infused acetylcholine (ACh; 0.1 1000 ng/kg/min) or methacholine (MCh; 0.1 A 100 ng/kg/min) in the presence of saline, the NO-scavenger and guanylate cyclase inhibitor met...

journal_title：Blood pressure

authors： Bruning TA,Chang PC,Kemme MJ,Vermeij P,Pfaffendorf M,van Zwieten PA

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:The lack of nocturnal BP fall less than 10% of the daytime, called non-dipper hypertension, is associated with increased cardiovascular morbidity and mortality. The aim of our study was to investigate atrial conduction time in patients with non-dipper hypertension using electromechanical coupling interval an...

journal_title：Blood pressure

authors： Ermis N,Acikgoz N,Cuglan B,Cansel M,Yagmur J,Tasolar H,Barutcu I,Pekdemir H,Ozdemir R

更新日期：2011-02-01 00:00:00

abstract：:Electrical stimulation of rostromedial portion of cerebellar fastigial nucleus elicits integrated cardiovascular effects, which are neurally and humorally mediated. In this study, we sought to demonstrate the anatomical substrates of the fastigial pressor response (FPR) in the rat. The response was electrophysiologica...

journal_title：Blood pressure

authors： Giuditta M,Ruggiero DA,Del Bo A

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVES:Cerebral white matter lesions (WMLs) are regarded to be subclinical ischemic changes of the cerebral parenchyma. Many previous studies have shown that baseline blood pressure (BP) is one of the most important factors for WMLs, but the relation between exercise BP and WMLs has not been fully evaluated. So, we...

journal_title：Blood pressure

authors： Yang WI,Kim IJ,Kim MS,Kim SH,Moon JY,Sung JH,Lim SW,Cha DH,Cho SY

更新日期：2018-06-01 00:00:00

abstract：:The aim of the present study was to compare insulin sensitivity and catecholamine responses to insulin in lean, hypertensive (HT) and normotensive (NT) premenopausal women. HT (BP 149 5/99 +/- 2 mmHg, n = 14) and NT (BP 128 +/- 4/81 +/- 2 mmHg, n = 12) were matched for age (46 +/- 1 vs. 47 +/- 1 years) and body mass i...

journal_title：Blood pressure

authors： Nordby G,Moan A,Kjeldsen SE,Eide IK,Os I

更新日期：1995-09-01 00:00:00

abstract：:Elevated intracellular free calcium (Ca2+) has been proposed as a mechanism of alcohol-induced hypertension from animal experimental studies, but this has not been confirmed in man. In the present study, intraplatelet Ca2+ concentration (plt.[Ca2+]i) was measured in 83 middle-aged men, and the associations between alc...

journal_title：Blood pressure

authors： Ikai E,Ishizaki M,Tsuritani I,Ishida M,Noborisaka Y,Yamada Y

更新日期：1995-03-01 00:00:00

abstract：PURPOSE:Event-based clinical outcome trials have shown limited evidence to support guidelines recommendations to lower blood pressure (BP) to <130/80 mmHg in middle-aged and elderly hypertensive patients with diabetes mellitus or with general high cardiovascular (CV) risk. We addressed this issue by post-hoc analysing ...

journal_title：Blood pressure

authors： Olsen E,Holzhauer B,Julius S,Kjeldsen SE,Larstorp ACK,Mancia G,Mehlum MH,Mo R,Rostrup M,Søraas CL,Zappe D,Weber MA

更新日期：2021-01-06 00:00:00

abstract：:Patients with severe hypertension with retinoscopic bilateral papilloedema only are not classically regarded as having malignant hypertension (MHT). We have encountered 23 such patients between 1965-1993, whilst over a similar period we have seen 315 patients who fulfilled the conventional criteria for MHT with bilate...

journal_title：Blood pressure

authors： Lip GY,Beevers M,Dodson PM,Beevers DG

更新日期：1995-11-01 00:00:00

abstract：:We wanted to investigate whether time to steady state was reached within 2 h of insulin infusion during isoglycemic hyperinsulinemic clamp, comparing the glucose uptake index (M/IG) with Bergman's insulin sensitivity index (Sip). We performed a 2-h oral glucose tolerance test and a 3-h isoglycemic hyperinsulinemic cla...

journal_title：Blood pressure

authors： Olsen MH,Andersen UB,Wachtell K,Ibsen H,Dige-Petersen H

更新日期：1999-01-01 00:00:00

abstract：:Sleep disordered breathing has increasingly been recognised as a frequent cause of ill-health in the community. Moderate or severe forms of the most common condition, obstructive sleep apnea (OSA), occur in up to 12% of the adult male population. A substantial body of literature has been published on the potential rel...

journal_title：Blood pressure

authors：

更新日期：1993-09-01 00:00:00

abstract：:One-thousand-four-hundred-and-fifty-three patients admitted to a teaching hospital, haemodynamically stable and not severely ill nor in significant pain, were interviewed within 48 h of admission and demographic data and a detailed drinking history were obtained. Supine blood pressures (BP) were recorded on the day fo...

journal_title：Blood pressure

authors： Howes JB,Ryan J,Fairbrother G,O'Neill K,Howes LG

更新日期：1997-03-01 00:00:00

abstract：:Losartan represent a novel approach in the treatment of hypertension. Clinical trials have reported a very low incidence of side effects. We describe two patients who developed increases in alanine/aspartate amino transferase of 8 and 15 times the upper normal limit, as well as thoracic pain, after a short time of tre...

journal_title：Blood pressure

authors： Nygaard B,Strandgaard S

更新日期：1996-05-01 00:00:00

abstract：:The study explored the relationship between time- and frequency-domain indices of cardiac autonomic control and 24 h blood pressure variability (BPV) in a sample of healthy men and women. Vagally mediated cardiac control was inversely related to 24 h BPV, and measures of cardiac autonomic control were better predictor...

journal_title：Blood pressure

authors： Thayer JF,Sollers JJ 3rd,Friedman BH,Koenig J

更新日期：2016-01-01 00:00:00

abstract：:In order to study the role of opioid receptors in two models of experimental hypertension the binding of 3H-naloxone to membranes prepared from discrete brain regions and spinal cord was determined. Renal hypertensive rats (RHR) were found to have a greater density of 3H-naloxone binding sites in the hippocampus and h...

journal_title：Blood pressure

authors： Widy-Tyszkiewicz E,Kotapski J,Czlonkowski A

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVE:There is an association between exercise systolic blood pressure (SBP) and cardiovascular disease and mortality. The aim of this study was to investigate this association, with 35 years of follow-up. METHODS:Through 1972-75, 2014 healthy, middle-aged men underwent thorough medical examination and a bicycle e...

journal_title：Blood pressure

authors： Mariampillai JE,Engeseth K,Kjeldsen SE,Grundvold I,Liestøl K,Erikssen G,Erikssen J,Bodegard J,Skretteberg PT

更新日期：2017-08-01 00:00:00

abstract：:Medullipin I (Med I) is a vasodepressor prohormone which is continuously elaborated into the renal venous effluent (RVE) of isolated rat kidneys perfused under high pressure. We have improved the yield of Med I by substituting saline for the albumin perfusate previously reported; and considerably improved refinement b...

journal_title：Blood pressure

authors： Brooks B,Byers LW,Muirhead EE,Muirhead M,Pitcock JA,Maddipati KR,Maxey KM

更新日期：1994-11-01 00:00:00

abstract：:Low compliance to therapeutic regimens can have serious impact on patient health. A variety of technologies such as tablet dispensers and reminders has been developed to improve compliance. The aim of this study was to assess the acceptance of patients and physicians with regard to the functions and usefulness of a re...

journal_title：Blood pressure

authors： Christensen A,Christrup LL,Fabricius PE,Chrostowska M,Wronka M,Narkiewicz K,Hansen EH

更新日期：2009-01-01 00:00:00

abstract：:Serotonin stimulates phospholipase A(2)(PLA(2)) leading to the production of prostaglandin products, several of which are vasoconstrictors. We hypothesised that the elevated vascular responsiveness to serotonin in deoxycorticosterone acetate (DOCA)-hypertensive rats is due in part to augmented production of vasoconstr...

journal_title：Blood pressure

authors： Kanagy NL,Mecca TE,Webb RC

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Hypertension is a global health threat and major cardiovascular risk. Various risk-prediction models for incident hypertension have been developed but not many of them have studied the risk-predictive value of life style factors in combination with cardiovascular biomarkers during long-term period of over 10...

journal_title：Blood pressure

authors： Terho A,Bloigu R,Bloigu A,Niemelä O,Tulppo M,Kesäniemi YA,Ukkola O

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To investigate if young normotensive subjects with a familial history of essential hypertension (FHH) or young borderline-hypertensive (BHT) subjects have a defect endothelial function. METHODS:Fifteen young (26 +/- 4 years) healthy normotensive (115 +/- 8/71 +/- 6 mmHg) subjects with a FHH, 31 matched healt...

journal_title：Blood pressure

authors： Millgård J,Hägg A,Sarabi M,Lind L

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:Essential hypertension and insulin resistance frequently coexist; cyclosporine A (CsA) is known to induce hypertension which has been used as a model for essential hypertension. The present study aimed to evaluate whether elevated blood pressure and insulin resistance coexist during CsA therapy to prove the ...

journal_title：Blood pressure

authors： Kutkuhn B,Hollenbeck M,Heering P,Koch M,Voiculescu A,Reinhard T,Grabensee B

更新日期：1997-01-01 00:00:00

abstract：:Northern Africans constitute one of the largest immigrant groups in France; however, limited data are available on their cardiovascular risk factors. We carried out a retrospective cross-sectional study in a French hypertension unit, comparing 719 patients born in Northern Africa to 3558 controls born in Europe, indiv...

journal_title：Blood pressure

authors： Lepoutre-Lussey C,Plouin PF,Steichen O

更新日期：2010-04-01 00:00:00

abstract：AIMS:To assess safety and efficacy of valsartan/amlodipine combination in hypertensive Taiwanese patients. METHODS:This 12-week, multi-center, prospective, observational, post-marketing study enrolled 1029 patients to receive valsartan/amlodipine combination alone or as add-on to other antihypertensives. Efficacy was ...

journal_title：Blood pressure

authors： Cheng SM,Mar GY,Huang SC,Chen CS,Hsieh CM,Huang LC,Ueng KC

更新日期：2012-07-01 00:00:00

abstract：:Hypertensive patients who are at high risk of developing cardiovascular (CV) complications have become the focus of modern treatment guidelines. The choice of antihypertensive therapies in these patients should be evidence-based: in particular, there should be evidence of a beneficial impact on CV events in addition t...

journal_title：Blood pressure

authors： Ruilope LM

更新日期：2002-01-01 00:00:00

abstract：:We compared the effects of amlodipine and verapamil slow release on autonomic responses to a 5-min mental arithmetic test (MST) in patients with mild to moderate hypertension. Twenty subjects received 8 weeks of verapamil slow release 240 mg or amlodipine 10 mg in a double-blind crossover design, both after 4 weeks' p...

journal_title：Blood pressure

authors： Sevre K,Lefrandt JD,Eide I,Smit AJ,Rostrup M

更新日期：2001-01-01 00:00:00

abstract：:This paper presents a review of experimental and clinical research on the contribution of hypertension to cochlear hearing loss. Hypertension is one of the crucial risk factors underlying pathophysiological processes taking place in the cochlea. Several mechanisms explaining these processes have been described, mainly...

journal_title：Blood pressure

authors： Przewoźny T,Gójska-Grymajło A,Kwarciany M,Gąsecki D,Narkiewicz K

更新日期：2015-01-01 00:00:00