Multispectral imaging autofluorescence microscopy for the analysis of lymph-node tissues.

abstract：:Hypericin is a naturally occurring photosensitizer, whose presence in plants has been responsible for cutaneous phototoxicity in grazing animals. The photosensitizing properties of this agent have recently been exploited in models for anti-tumor and anti-viral activity. The cytotoxicity of hypericin and light was asse...

journal_title：Photochemistry and photobiology

authors： Yu H,Wolford ST,Kegode R,Zhao W,Osweller GD

更新日期：1996-07-01 00:00:00

abstract：:Schinus terebinthifolius is a plant rich in phenolic compounds, which have antioxidant properties and can provide new opportunities for treatment and prevention of diseases mediated by ultraviolet radiation like photoaging and skin cancer. The aim of this study was to evaluate the photoprotective potential and ex vivo...

journal_title：Photochemistry and photobiology

authors： Bulla MK,Hernandes L,Baesso ML,Nogueira AC,Bento AC,Bortoluzzi BB,Serra LZ,Cortez DA

更新日期：2015-05-01 00:00:00

abstract：:Mitochondria have been implicated as a primary subcellular site of porphyrin localization and photodestruction. However, other organelles including the cell membrane, lysosomes and nucleus have been shown to be damaged by hematoporphyrin derivative (HpD) photosensitized destruction as well. In this study we attempted ...

journal_title：Photochemistry and photobiology

authors： Shulok JR,Wade MH,Lin CW

更新日期：1990-04-01 00:00:00

abstract：:Photosensitizer-functionalized reduced graphene oxide (rGO) nanoparticles are promising materials for photodynamic therapy in cancer management. In this study, rGO is synthesized by a green route employing glucose as the reducing agent and functionalized with photosensitizer, protoporphyrin IX (PPIX) in a convenient, ...

journal_title：Photochemistry and photobiology

authors： Shuvra Smita S,Das A,Barui A

更新日期：2020-11-01 00:00:00

abstract：:We present an in vivo study of the optical properties of melanin present in melanocytic nevi of human subjects with Fitzpatrick skin type III (Caucasian descent) using optical spectroscopy. We show that the melanin absorption spectrum exhibits an exponential dependence on wavelength with a decay constant which follows...

journal_title：Photochemistry and photobiology

authors： Zonios G,Dimou A

更新日期：2009-01-01 00:00:00

abstract：:An important step in predicting the effects of future increases in UV radiation (UVR) is to evaluate the mechanisms that organisms use to prevent and repair DNA damage and determine how those mechanisms influence UVR sensitivity. Damage is prevented to varying degrees through photoprotection and repaired via two main ...

journal_title：Photochemistry and photobiology

authors： Olson MH,Mitchell DL

更新日期：2006-03-01 00:00:00

abstract：:Fluoresceinyl cypridina luciferin analog (FCLA) is a chemiluminescence (CL) probe for detecting reactive oxygen species (ROS). Its efficiency for detecting singlet oxygen (1O2) can be significantly enhanced in the presence of human serum albumin (HSA). This phenomenon may apply to important applications for both resea...

journal_title：Photochemistry and photobiology

authors： Zhou J,Xing D,Chen Q

更新日期：2006-07-01 00:00:00

abstract：:An approximate formula for the UV Index (UVI) under cloud-free, unpolluted, low surface albedo conditions is: UVI approximately 12.5mu(o)(2.42)(Omega/300)(-1.23) where mu(o) is the cosine of the solar zenith angle and Omega is the total vertical ozone column (in Dobson Units, DU). The dependence on mu(o) and Omega is ...

journal_title：Photochemistry and photobiology

authors： Madronich S

更新日期：2007-11-01 00:00:00

abstract：:Various photosensitizers were grafted by conventional peptide coupling methods to functionalized silica with several macroscopic shapes (powders, films) or embedded in highly transparent and microporous silica xerogel monoliths. Owing to the transparency and free-standing shape of the monoliths, the transient species ...

journal_title：Photochemistry and photobiology

authors： Ronzani F,Saint-Cricq P,Arzoumanian E,Pigot T,Blanc S,Oelgemöller M,Oliveros E,Richard C,Lacombe S

更新日期：2014-03-01 00:00:00

abstract：:Cultured cells accumulate acridine orange (AO), which is a weak basic dye and a photosensitizer, in lysosomes and other acidic compartments. During exposure to blue light, AO-loaded macrophages show decreasing red granular fluorescence and increasing green diffuse fluorescence. This is hypothesized to represent peroxi...

journal_title：Photochemistry and photobiology

authors： Zdolsek JM,Olsson GM,Brunk UT

更新日期：1990-01-01 00:00:00

abstract：:We have been able to identify a blue fluorophore from the low-molecular weight soluble fraction of human adult nondiabetic brunescent cataract lenses as xanthurenic acid 8-O-beta-D-glucoside (XA8OG) (excitation = 338 nm and emission = 440 nm). To determine the role of this fluorophore in the lens, we have examined its...

journal_title：Photochemistry and photobiology

authors： Thiagarajan G,Shirao E,Ando K,Inoue A,Balasubramanian D

更新日期：2002-09-01 00:00:00

abstract：:DNA UVB dosimeters, consisting of minidots of dried bacteriophage DNA placed on a UV-transparent polymer film, were analyzed by polymerase chain reactions (PCR). Ultraviolet-B dosimetry obtained with amplification of phage lambda DNA of segments of 1.08 kilobase pairs (kbp) and 2.24 kbp was compared with that obtained...

journal_title：Photochemistry and photobiology

authors： Yoshida H,Regan JD

更新日期：1997-11-01 00:00:00

abstract：:This paper reviews briefly the evidence for an association between various measures of UV radiation (UVR) exposure and the development of cancer. Issues such as data quality, study design, measurement variation, comparability of studies, and quantification of UV exposure in relation to skin cancer are discussed. A ran...

journal_title：Photochemistry and photobiology

authors： Berwick M,Kesler D

更新日期：2005-11-01 00:00:00

abstract：:A series of luminescent ion exchanged zeolite are synthesized by introducing various ions into NaY zeolite. Monometal ion (Eu(3+), Tb(3+), Ce(3+), Y(3+), Zn(2+), Cd(2+), Cu(2+)) exchanged zeolite, rare-earth ion (Eu(3+), Tb(3+), Ce(3+)) exchanged zeolite modified with Y(3+) and rare-earth ion (Eu(3+), Tb(3+), Ce(3+)) ...

journal_title：Photochemistry and photobiology

authors： Duan TW,Yan B

更新日期：2014-05-01 00:00:00

abstract：:Unidirectional blue light directs the rhizoid-thallus axis in the apolar zygote of the brown alga, Silvetia compressa. This effect is mediated by an increase in the intracellular concentration of guanosine 3', 5'-cyclic monophosphate. In this study we show the identification of a rhodopsin-like protein, by means of an...

journal_title：Photochemistry and photobiology

authors： Gualtieri P,Robinson KR

更新日期：2002-01-01 00:00:00

abstract：:Reactive nitrogen species, produced during the process of inflammation induced by various factors including UV radiation, modify amino acids in crucial proteins. It is assumed that skin tissue is more likely to be modified, as it is located at the outer layer of a body that is exposed to UV radiation on a daily basis....

journal_title：Photochemistry and photobiology

authors： Ishitsuka Y,Maniwa F,Koide C,Douzaki N,Kato Y,Nakamura Y,Osawa T

更新日期：2007-05-01 00:00:00

abstract：:Low-level light therapy has been used in health care as a therapeutic strategy for different diseases. However, its effects on cancer are controversial. This work evaluated the effects of three energies on breast cancer-bearing mice after a single red light-emitting diode (LED) irradiation. 4T1 cells were inoculated i...

journal_title：Photochemistry and photobiology

authors： Pereira ST,Silva CR,Nuñez SC,Ribeiro MS

更新日期：2020-10-03 00:00:00

abstract：:Photosensitizer (PS)-antibody conjugates (photoimmunoconjugates, PICs) enable cancer cell-targeted photodynamic therapy (PDT). Nonspecific chemical bioconjugation is widely used to synthesize PICs but gives rise to several shortcomings. The conjugates are heterogeneous, and the process is not easily reproducible. More...

journal_title：Photochemistry and photobiology

authors： Sadiki A,Kercher EM,Lu H,Lang RT,Spring BQ,Zhou ZS

更新日期：2020-05-01 00:00:00

abstract：:The immunological consequences of exposure to UVA (320-400 nm) radiation are unclear. This study describes the relationship between the generation of epidermal cis-urocanic acid and the ability to respond to a contact-sensitizing agent, in hairless mice exposed to different UV radiation sources, which incorporate succ...

journal_title：Photochemistry and photobiology

authors： Reeve VE,Boehm-Wilcox C,Bosnic M,Cope R,Ley RD

更新日期：1994-09-01 00:00:00

abstract：:Our recent study follows up an earlier one which demonstrated hypericin-mediated photocytotoxic effects on HT-29 adenocarcinoma cells by light fractionation with a longer dark pause between two unequal light doses (Sackova, A. [2005] Photochem. Photobiol.81, 1411-1416). Here, we present closer study on events invoked ...

journal_title：Photochemistry and photobiology

authors： Kuliková L,Mikeš J,Hýžďalová M,Palumbo G,Fedoročko P

更新日期：2010-11-01 00:00:00

abstract：:It has previously been demonstrated that chronic low-dose solar-simulated UV radiation could induce both local and systemic immunosuppression as well as tolerance to a topically applied hapten. In this study, we have used a chronic low-dose UV-irradiation protocol to investigate the effects of UVA on the skin immune s...

journal_title：Photochemistry and photobiology

authors： Bestak R,Halliday GM

更新日期：1996-12-01 00:00:00

abstract：:A careful study of the linoleic acid hydroperoxide (LOOH) profile obtained upon peroxidation of linoleic acid (LA) photosensitized by tiaprofenic acid (TPA) and analogous ketones has been undertaken to distinguish between type-I and type-II photoperoxidation mechanisms. 1,4-Cyclohexadiene and 1,2-dimethylcyclohexa-2,5...

journal_title：Photochemistry and photobiology

authors： Samadi A,Martínez LA,Miranda MA,Morera IM

更新日期：2001-04-01 00:00:00

abstract：:The protein environments surrounding the retinal tune electronic absorption maximum from 350 to 630 nm. Hybrid quantum mechanical/molecular mechanical (QM/MM) methods can be used in calculating excitation energies of retinal in its native protein environments and in studying the molecular basis of spectral tuning. We ...

journal_title：Photochemistry and photobiology

authors： Altun A,Yokoyama S,Morokuma K

更新日期：2008-07-01 00:00:00

abstract：:Cellular autofluorescence spectra were monitored in a single-beam gradient force optical trap ("optical tweezers") in order to probe the physiological effects of near infrared and UVA (320-400 nm) microirradiation. Prior to trapping, Chinese hamster ovary cells exhibited weak UVA-excited autofluorescence with maxima a...

journal_title：Photochemistry and photobiology

authors： König K,Liu Y,Sonek GJ,Berns MW,Tromberg BJ

更新日期：1995-11-01 00:00:00

abstract：:We have compared the cytotoxicity of daunomycin in vitro to highly differentiated normal epithelial cells (Fisher rat thyroid cells, FRTL-5) and to two neoplastic cell lines, a thyroid carcinoma (TK-6) and its lung metastasis (MPTK-6). Whereas the cell lines are equally sensitive to the drug in the dark, if irradiated...

journal_title：Photochemistry and photobiology

authors： Andreoni A,Colasanti A,Kisslinger A,Mastrocinque M,Portella G,Riccio P,Roberti G

更新日期：1993-05-01 00:00:00

abstract：:We previously reported that a low level of lysosomal photodamage potentiated the phototoxic effect of subsequent mitochondrial photodamage mediated by the benzoporphyrin derivative (BPD) in murine hepatoma 1c1c7 cells. This was attributed to release of Ca2+ from damaged lysosomes and a calpain-mediated conversion of t...

journal_title：Photochemistry and photobiology

authors： Kessel D,Reiners JJ Jr

更新日期：2017-11-01 00:00:00

abstract：:Conventional brain-imaging modalities may be limited by high cost, difficulty of bedside use, noncontinuous operation, invasiveness or an inability to obtain measurements of tissue function, such as oxygenation during stroke. Our goal was to develop a bedside clinical device able to generate continuous, noninvasive, t...

journal_title：Photochemistry and photobiology

authors： Hintz SR,Benaron DA,van Houten JP,Duckworth JL,Liu FW,Spilman SD,Stevenson DK,Cheong WF

更新日期：1998-09-01 00:00:00

abstract：:Normal hematopoietic progenitor cells from 129S6/SvEv mice are substantially less sensitive to Merocyanine 540 (MC540)-mediated photodynamic therapy (PDT) than hematopoietic progenitors from sex- and age-matched C57BL/6 mice. When exposed to a combination of MC540 and light commonly used for the extracorporeal purging...

journal_title：Photochemistry and photobiology

authors： Tsujino I,Sieber F

更新日期：2000-12-01 00:00:00

abstract：:Multichromophoric dyes for use in tumor imaging have been synthesized and photophysically characterized. Structurally, these dyes are dyads and triads that consist of one or two carotenoid polyenes covalently attached to hematoporphyrin (HP) or hematoporphyrin dimethyl ester (HPDME) moieties via ester linkages. The gr...

journal_title：Photochemistry and photobiology

authors： Tatman D,Liddell PA,Moore TA,Gust D,Moore AL

更新日期：1998-10-01 00:00:00

abstract：:Photochemo and photodynamic therapies are minimally invasive approaches for the treatment of cancers and powerful weapons for competing bacterial resistance to antibiotics. Synthetic and naturally occurring quinazolinones are considered privileged anticancer and antibacterial agents, with several of them to have emerg...

journal_title：Photochemistry and photobiology

authors： Panagopoulos A,Balalas T,Mitrakas A,Vrazas V,Katsani KR,Koumbis AE,Koukourakis MI,Litinas KE,Fylaktakidou KC

更新日期：2021-01-01 00:00:00