Alterations in plasma sialyltransferase levels in patients with neoplastic disease.

Abstract:

:Levels of glycoprotein:sialyltransferase activity (EC 2.4.99.1; CMP-acetyl-neuraminate:D-galactosyl-glycoprotein N-acetylneuraminyl-transferase) were measured in plasma of patients with neoplastic disease, and were found elevated above normal control values in 85% of patients examined. There was a correlation between enzyme levels and course of disea-e in 46 of 57 patients studied serially during therapy. Plasma sialyltransferase may be a useful marker enzyme for monitoring effectiveness of therapeutic programs for disseminated neoplasms.

journal_name

Cancer

journal_title

Cancer

authors

Henderson M,Kessel D

doi

10.1002/1097-0142(197703)39:3<1129::aid-cncr282039

subject

Has Abstract

pub_date

1977-03-01 00:00:00

pages

1129-34

issue

3

eissn

0008-543X

issn

1097-0142

journal_volume

39

pub_type

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