Effects of submucosal administration of endothelin-3 on rat gastric mucosa.

abstract：BACKGROUND:Matrix metalloproteinases (MMPs) are one of the major classes of proteolytic enzymes involved in tumor invasion and metastasis, being inhibited by naturally occurring tissue inhibitors of metalloproteinases (TIMPs). In this study, we examined the expression of MMP-2, MMP-9, membrane-type 1 (MT1)-MMP, TIMP-1,...

journal_title：Journal of gastroenterology

authors： Shim KN,Jung SA,Joo YH,Yoo K

更新日期：2007-02-01 00:00:00

abstract：:We report a case of pancreas head carcinoma associated with fat replacement of the body and tail. A 68-year-old man presented with obstructive jaundice and was admitted to our hospital. Ultrasonography and computed tomography showed pancreas head tumor with a neighboring cystic lesion and fatty replacement of parenchy...

journal_title：Journal of gastroenterology

authors： Toyama N,Kamiyama H,Suminaga Y,Namai K,Ota M,Konishi F

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Abrogating tolerance is a critical step in the pathogenesis of Crohn's disease (CD). T cell-anergy is one of the main mechanisms of tolerance and is regulated by the gene related to anergy in lymphocytes (GRAIL). This study investigated the expressions and regulation of GRAIL in CD and murine colitis models....

journal_title：Journal of gastroenterology

authors： Mukai A,Iijima H,Hiyama S,Fujii H,Shinzaki S,Inoue T,Shiraishi E,Kawai S,Araki M,Hayashi Y,Kondo J,Mizushima T,Kanto T,Egawa S,Nishida T,Tsujii M,Takehara T

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The (13)C-urea breath test (UBT) is a simple breath test for the diagnosis of Helicobacter pylori infection, but several factors have been reported to affect the results of this test. In this study, the effects of the antiulcer drugs used in Japan on the results of UBT were determined. METHODS:The subjects ...

journal_title：Journal of gastroenterology

authors： Murakami K,Sato R,Okimoto T,Watanabe K,Nasu M,Fujioka T,Kodama M,Kagawa J

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:A combination of hepatitis B immunoglobulin and nucleos(t)ide analogues is the current standard of care for controlling hepatitis B recurrence after orthotopic liver transplantation (OLT). However, frequent immunoglobulin treatment is expensive and inconvenient. This study investigated the efficacy of hepati...

journal_title：Journal of gastroenterology

authors： Takaki A,Yagi T,Yasunaka T,Sadamori H,Shinoura S,Umeda Y,Yoshida R,Sato D,Nobuoka D,Utsumi M,Yasuda Y,Nakayama E,Miyake Y,Ikeda F,Shiraha H,Nouso K,Fujiwara T,Yamamoto K

更新日期：2013-12-01 00:00:00

abstract：:We describe a gastric carcinoma cell line that has been maintained in vitro for more than 10 years and retains the capacity to produce a large amount of alpha-fetoprotein. This cell line was isolated from a metastatic lymph node of a 63-year-old male patient with advanced gastric carcinoma (T2N3P0H0M0) who showed high...

journal_title：Journal of gastroenterology

authors： Sekiguchi M,Fujii Y,Saito A,Suzuki T,Shiroko Y,Nakamura H,Hasumi K

更新日期：1995-10-01 00:00:00

abstract：:We measured urokinase-type plasminogen activator (u-PA) plasma levels in patients with various chronic liver diseases, including hepatocellular carcinoma (HCC), also measuring these levels in healthy volunteers. Plasma u-PA levels in the group of patients with decompensated liver cirrhosis (mean modified Pugh score of...

journal_title：Journal of gastroenterology

authors： Sato S,Higashi T,Ouguchi S,Hino N,Tsuji T

更新日期：1994-12-01 00:00:00

abstract：:We used positron emission tomography with 2-deoxy-2-[(18)F]fluoro- d-glucose (FDG-PET) in the diagnosis of two cases of malignant intraductal papillary mucinous tumor (IPMT) of the pancreas. A 56-year-old man and a 72-year-old man, both with tumors in the pancreatic head, were referred to Akita University Medical Cent...

journal_title：Journal of gastroenterology

authors： Yoshioka M,Sato T,Furuya T,Shibata S,Andoh H,Asanuma Y,Hatazawa J,Koyama K

更新日期：2003-01-01 00:00:00

abstract：:This paper describes a program of research undertaken by the Inflammatory Bowel Disease Study Group at the Royal Free Hospital School of Medicine. The Group has tested the hypothesis that the primary pathological abnormality in Crohn's disease is in the mesenteric blood supply. The first experiments involved microcorr...

journal_title：Journal of gastroenterology

authors： Pounder RE

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Ultrasound-guided procedures are sometimes of limited use because the tumor is located under the diaphragm or near the surface of the liver. We investigated the safety and efficacy of radiofrequency ablation (RFA) with artificial pleural effusion and/or artificial ascites. METHODS:Between January 2002 and M...

journal_title：Journal of gastroenterology

authors： Uehara T,Hirooka M,Ishida K,Hiraoka A,Kumagi T,Kisaka Y,Hiasa Y,Onji M

更新日期：2007-04-01 00:00:00

abstract：:The spontaneous passage of colon cast from a 76-year-old Japanese female patient is reported. Macroscopically, the colon case was shaped like the airbladder of a fish. Histopathologically, the cast consisted of degenerated colonal mucosa, including glands. No inflammatory reaction was apparent. The patient lacked any ...

journal_title：Journal of gastroenterology

authors： Yoshiji H,Nakae D,Sugiya R,Mizumoto Y,Tsutsumi M,Hiriguchi K,Yokose Y,Sakurai R,Fukui H,Tsujii T

更新日期：1994-02-01 00:00:00

abstract：:Primary T/natural killer (NK) cell lymphoma of the colon is extremely rare. Despite the advances in histological and immunophenotypic studies, the diagnosis of primary T/NK cell lymphoma of the colon can be delayed because the early symptoms and colonoscopic findings may be very similar to those of inflammatory bowel ...

journal_title：Journal of gastroenterology

authors： Kim HS,Lee DK,Baik SK,Kwon SO,Cho MY,Ko YH

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:White adipose tissue (WAT) is important for the maintenance of metabolic homeostasis, and metabolic syndrome is sometimes associated with WAT dysfunction in humans and animals. WAT reportedly plays a key, beneficial role in the maintenance of glucose and lipid homeostasis during de novo lipogenesis (DNL). Pu...

journal_title：Journal of gastroenterology

authors： Cai X,Hayashi S,Fang C,Hao S,Wang X,Nishiguchi S,Tsutsui H,Sheng J

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The ability of serum infliximab level to predict clinical outcome in infliximab therapy in Crohn's disease is unclear. Here, we aimed to clarify the correlation between the timing of loss of response (LOR) to treatment and a decrease in serum infliximab level, and, in addition, to identify an indicator of in...

journal_title：Journal of gastroenterology

authors： Hibi T,Sakuraba A,Watanabe M,Motoya S,Ito H,Sato N,Yoshinari T,Motegi K,Kinouchi Y,Takazoe M,Suzuki Y,Matsumoto T,Kawakami K,Matsumoto T,Hirata I,Tanaka S,Ashida T,Matsui T

更新日期：2014-02-01 00:00:00

abstract：:Both reflex and sensory mechanisms control the function of the stomach, and disturbances in these mechanisms may explain the pathophysiology of disorders of gastric function. The objective of this report is to perform a literature-based critical analysis of new, relevant or conflicting information on gastric sensitivi...

journal_title：Journal of gastroenterology

authors： Azpiroz F,Feinle-Bisset C,Grundy D,Tack J

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Percutaneous microwave ablation and radiofrequency ablation are two commonly used modalities for the treatment of hepatocellular carcinoma; however, comparisons of them have not been documented adequately. METHODS:Of 102 patients with biopsy-proved hepatocellular carcinoma, 49 (98 nodules) were treated perc...

journal_title：Journal of gastroenterology

authors： Lu MD,Xu HX,Xie XY,Yin XY,Chen JW,Kuang M,Xu ZF,Liu GJ,Zheng YL

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:A prospective, randomized study was performed to determine whether gemcitabine infusion at a low dose (250 mg/m2) is comparable or superior to the standard-dose infusion (1000 mg/m2) in terms of the survival period, clinical benefit, and frequency of adverse effects in patients with advanced pancreatic adeno...

journal_title：Journal of gastroenterology

authors： Sakamoto H,Kitano M,Suetomi Y,Takeyama Y,Ohyanagi H,Nakai T,Yasuda C,Kudo M

更新日期：2006-01-01 00:00:00

abstract：:An association between macrovascular thrombosis and idiopathic inflammatory bowel disease has been described, although very few well-documented cases have been published. We report on a 39-year-old woman who presented with right hemifacial and upper limb edema that was shown to be due to an extensive right brachioceph...

journal_title：Journal of gastroenterology

authors： Ribeiro JM,Rebocho L,Lucas MB,Campos P,Victorino RM

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Neovascularization was shown to be critically involved in the progression of multiple cancers, and treatment approaches targeting tumor-associated neovascularization provide convincing results in recent years in some tumor entities. However, little is known about the tumor-associated neovascularization in hi...

journal_title：Journal of gastroenterology

authors： Thelen A,Scholz A,Benckert C,Schröder M,Weichert W,Wiedenmann B,Neuhaus P,Jonas S

更新日期：2008-01-01 00:00:00

abstract：:Perianal fistulae are frequently seen complications in Crohn's disease. Although surgical procedures such as Seton's method have been devised, many patients still suffer from fistulae that are resistant to conventional therapy. We administered oral adsorbent to a patient with disease Crohn's who had a complicated peri...

journal_title：Journal of gastroenterology

authors： Tsujikawa T,Araki Y,Makino J,Uda K,Ihara T,Sasaki M,Fujiyama Y,Bamba T

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Polymorphisms in the gene for interleukin 1beta (IL-1B) have been found to increase the risks of gastric cancer and its precursors in response to Helicobacter pylori infection in white populations. however, there has been no independent confirmation of the role of IL-1B markers in gastric cancer patients fro...

journal_title：Journal of gastroenterology

authors： Lee KA,Ki CS,Kim HJ,Sohn KM,Kim JW,Kang WK,Rhee JC,Song SY,Sohn TS

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The search is on to find more effective drug regimens for patients with severe ulcerative colitis, as conventional drugs such as sulfasalazine and its congeners fail to prevent relapse in a significant number of patients. Azathioprine has also been reported to be useful as a steroid-sparing drug in patients ...

journal_title：Journal of gastroenterology

authors： Sood A,Kaushal V,Midha V,Bhatia KL,Sood N,Malhotra V

更新日期：2002-01-01 00:00:00

abstract：:Inconsistencies and omissions in current explanations for the well known depressions of gastric acid secretion and blood gastrin levels following acidification by antral stimulants are discussed. Evidence is presented which favors a reciprocal sensitivity relationship between the fundic mucosa and the antral G cells, ...

journal_title：Journal of gastroenterology

authors： Magee DF

更新日期：1996-10-01 00:00:00

abstract：:We report a case of gastrojejunal fistula caused by benign gastric ulcer, a very rare condition. The patient was an 81-year-old-woman who had had multiple recurrences of gastric ulcer. She also had diabetes mellitus. She was admitted to our hospital because of a left femoral head fracture, necessitating a mechanical b...

journal_title：Journal of gastroenterology

authors： Matsuoka M,Yoshida Y,Hayakawa K,Fukuchi S

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:There have been few reports on hepatocellular carcinoma (HCC) in nonalcoholic steatohepatitis (NASH) and the natural history of NASH. Accordingly, we assessed the clinical features of HCC in NASH, the risk factors for HCC, and natural history of NASH with advanced fibrosis. PATIENTS AND METHODS:There were 3...

journal_title：Journal of gastroenterology

authors： Hashimoto E,Yatsuji S,Tobari M,Taniai M,Torii N,Tokushige K,Shiratori K

更新日期：2009-01-01 00:00:00

abstract：:Using commercial quantitative assays, quantitative hepatitis B surface antigen (qHBsAg) has improved our understanding and management of chronic hepatitis B (CHB). The HBsAg level is highest in the immune tolerance phase, starts to decline during the immune clearance phase, and decreases slowly but progressively after...

journal_title：Journal of gastroenterology

authors： Tseng TC,Kao JH

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Previous studies investigating the impact of tumor location on colorectal cancer prognosis only compared two groups by location, e.g., 'right-sided colon vs. left-sided colon,' 'colon vs. rectum,' and 'right-sided (right-sided colon) vs. left-sided (left-sided colon and rectum).' This nationwide multicenter ...

journal_title：Journal of gastroenterology

authors： Shida D,Inoue M,Tanabe T,Moritani K,Tsukamoto S,Yamauchi S,Sugihara K,Kanemitsu Y

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:There have been few epidemiological studies on gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in Japan. METHODS:We examined the epidemiology of GEP-NETs [pancreatic endocrine tumors (PETs) and gastrointestinal neuroendocrine tumors (GI-NETs)] in Japan in 2005 using a nationwide stratified random sa...

journal_title：Journal of gastroenterology

authors： Ito T,Sasano H,Tanaka M,Osamura RY,Sasaki I,Kimura W,Takano K,Obara T,Ishibashi M,Nakao K,Doi R,Shimatsu A,Nishida T,Komoto I,Hirata Y,Nakamura K,Igarashi H,Jensen RT,Wiedenmann B,Imamura M

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The dynamic change in gastric emptying on a minute-by-minute basis (gastric velocity) is evaluated by the 13C-octanoate breath test with deconvolution analysis. However, deconvolution is impractical, because it requires dual experiments to obtain 13CO2 excretion profiles following intraduodenal and oral admi...

journal_title：Journal of gastroenterology

authors： Sanaka M,Yamamoto T,Osaki Y,Kuyama Y

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Gastric complications of indomethacin involve generation of reactive oxygen species, which induce gastric mucosal injury via lipid peroxidation of cell membranes. Peroxidation by reactive oxygen species alters the amounts of unsaturated fatty acids in the cell membrane and thus affects membrane fluidity. Ind...

journal_title：Journal of gastroenterology

authors： Kaneko T,Matsui H,Shimokawa O,Nakahara A,Hyodo I

更新日期：2007-12-01 00:00:00