Primary appendiceal malignancy mimicking advanced stage ovarian carcinoma: a case series.

abstract：:Ovarian cancer is the leading cause of gynecologic cancer deaths in the U.S. The concept of intraperitoneal drug delivery for therapy of intraperitoneal cancers, such as ovarian cancer, arose in the 1960s. The field of intraperitoneal cisplatin therapy for ovarian cancer was initiated in the late 1970s and early 1980s...

journal_title：Gynecologic oncology

authors： Alberts DS,Markman M,Muggia F,Ozols RF,Eldermire E,Bookman MA,Chen T,Curtin J,Hess LM,Liebes L,Young RC,Trimble E

更新日期：2006-12-01 00:00:00

abstract：:One of the most prevalent potential therapeutic targets for women with endometrioid endometrial cancer (EC) is the estrogen receptor (ER)/progesterone receptor (PR) pathway. Despite a high proportion of endometrioid ECs being ER and/or PR positive, endocrine therapy is only effective in a minority of women with EC and...

journal_title：Gynecologic oncology

authors： Jerzak KJ,Duska L,MacKay HJ

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Timely surgery has been shown to impact outcome in endometrial cancer patients. Social determinants of health (SDH) are associated with adverse cancer outcomes. We sought to evaluate the association of SDH with surgical treatment indicators in endometrial cancer patients in a public healthcare system. METHOD...

journal_title：Gynecologic oncology

authors： Helpman L,Pond GR,Elit L,Anderson LN,Seow H

更新日期：2020-11-01 00:00:00

abstract：:Non-healing wounds represent a significant cause of morbidity and mortality for a large portion of the adult population. Wounds that fail to heal are entrapped in a self-sustaining cycle of chronic inflammation leading to the destruction of the extracellular matrix. Among cancer patients, malnutrition, radiation, phys...

journal_title：Gynecologic oncology

authors： Menke MN,Menke NB,Boardman CH,Diegelmann RF

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the utility of amiodarone and its derivative dronedarone as novel drug repositioning candidates in EOC and to determine the potential pathways targeted by these drugs. METHODS:Drug-predict bioinformatics platform was used to assess the utility of amiodarone as a novel drug-repurposing candidate i...

journal_title：Gynecologic oncology

authors： Belur Nagaraj A,Joseph P,Kovalenko O,Wang Q,Xu R,DiFeo A

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to estimate the efficacy of an intensive CDP program, as well as to identify the predictors associated with lymphedema severity and response to CDP in lower limb lymphedema (LLL) after pelvic cancer therapy. METHODS:We performed a retrospective review of post-pelvic cancer LLL patie...

journal_title：Gynecologic oncology

authors： Liao SF,Li SH,Huang HY

更新日期：2012-06-01 00:00:00

abstract：:A retrospective evaluation of 87 cases of uterine sarcoma treated during 1965-1980 at two Swedish hospitals has been made. Adjuvant postoperative radiotherapy has been compared with adjuvant chemotherapy. Various types of combination treatments were also evaluated. Both types of adjuvant therapy seem to reduce the fai...

journal_title：Gynecologic oncology

authors： Sorbe B

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVE:Our purpose was to determine the mRNA and protein expression of cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2) in ovarian tumors and normal ovaries of the hen, which is an excellent model for human ovarian cancer. Tissue concentrations of prostaglandin E(2) (PGE2) and PGE2 metabolites were also determi...

journal_title：Gynecologic oncology

authors： Urick ME,Johnson PA

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a classical glycolytic protein. A higher level of GAPDH mRNA was found in lung, pancreas, and prostate cancers, but in cervical carcinoma there have not been any reports about the level of GAPDH gene expression. So, we tried to investigate the GAPDH gene exp...

journal_title：Gynecologic oncology

authors： Kim JW,Kim SJ,Han SM,Paik SY,Hur SY,Kim YW,Lee JM,Namkoong SE

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to analyze risk factors for septic complications during adjuvant chemotherapy and their impact on survival in patients with advanced epithelial ovarian cancer treated with neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS). METHODS:We retrospectively revie...

journal_title：Gynecologic oncology

authors： Son JH,Lee JH,Jung JA,Kong TW,Paek J,Chang SJ,Ryu HS

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:Preoperative leukocytosis is known to be a negative prognostic factor for several gynecologic malignancies, but its relationship with epithelial ovarian carcinoma (EOC) is unknown. We sought to evaluate the prognostic implications of preoperative leukocytosis for women with EOC. METHODS:We retrospectively re...

journal_title：Gynecologic oncology

authors： So KA,Hong JH,Jin HM,Kim JW,Song JY,Lee JK,Lee NW

更新日期：2014-03-01 00:00:00

abstract：:Advances in surgery and chemotherapy have improved the 5-year survival for patients with epithelial ovarian cancer, but have not impacted on the ultimate rate of cure in a disease that is diagnosed in late stage and that recurs in the majority of patients. "Omic" technologies promise to define genetically driven aberr...

journal_title：Gynecologic oncology

authors： Ashworth A,Balkwill F,Bast RC,Berek JS,Kaye A,Boyd JA,Mills G,Weinstein JN,Woolley K,Workman P

更新日期：2008-03-01 00:00:00

abstract：:The analysis of the lytic mechanism initiated by TNFalpha in three human ovarian cell lines (CAOV-3, SK-OV-3, and OVCAR-3) and in three human cervical cell lines (SIHa, HT-3, and ME-180) in the presence of inhibitors of protein synthesis indicates that this lytic mechanism is similar to the protein synthesis-independe...

journal_title：Gynecologic oncology

authors： Powell CB,Scott JH,Collins JL

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:The AGO-OVAR16 study was designed to test the efficacy, safety, and tolerability of pazopanib maintenance after first-line chemotherapy in patients with newly diagnosed advanced ovarian cancer (AOC). METHODS:Nine hundred and forty patients with histologically confirmed AOC, International Federation of Gyneco...

journal_title：Gynecologic oncology

authors： Vergote I,du Bois A,Floquet A,Rau J,Kim JW,Del Campo JM,Friedlander M,Pignata S,Fujiwara K,Colombo N,Mirza MR,Monk BJ,Tsibulak I,Calvert PM,Herzog TJ,Hanker LC,Meunier J,Lee JY,Bologna A,Carrasco-Alfonso MJ,Harter

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:The present study was planned to measure preoperative levels of soluble urokinase plasminogen activator receptor (suPAR) in plasma from patients with gynecological diseases, and to test for a relationship to clinical and biochemical patient characteristics. METHODS:Using a specific and sensitive kinetic ELIS...

journal_title：Gynecologic oncology

authors： Riisbro R,Stephens RW,Brünner N,Christensen IJ,Nielsen HJ,Heilmann L,von Tempelhoff GF

更新日期：2001-09-01 00:00:00

abstract：:Ninety-two patients with early invasive carcinoma of the cervix (5 mm or less) treated between July 1977 and June 1990 are reviewed. Eighty patients had squamous cell carcinomas and 12 had adenocarcinomas. The diagnosis was established by conization in 77 of 92 (83.6%) patients. Thirty-six patients (39%) had a depth o...

journal_title：Gynecologic oncology

authors： Jones WB,Mercer GO,Lewis JL Jr,Rubin SC,Hoskins WJ

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:To investigate whether the number of lymph nodes obtained during lymphadenectomy affects the survival of patients with intermediate- or high-risk endometrioid-type endometrial cancer. METHODS:A total of 476 patients who were diagnosed with FIGO stage IB to IIIC2 endometrioid adenocarcinoma through surgical s...

journal_title：Gynecologic oncology

authors： Kim TH,Kim HS,Kim TJ,Chang SJ,Kim DY,Ryu SY,Kim BG,Kim YT,Bae DS,Ryu HS,Nam JH

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:We wanted to identify genes up-regulated in ovarian tumors that might serve as early markers for ovarian cancer. One promising focus is the family of genes that encode secreted proteases, which play essential roles in tumor invasion and metastasis. Kallikrein 10 (KLK10) is a member of the kallikrein family of...

journal_title：Gynecologic oncology

authors： Shvartsman HS,Lu KH,Lee J,Lillie J,Deavers MT,Clifford S,Wolf JK,Mills GB,Bast RC Jr,Gershenson DM,Schmandt R

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:The objective was to determine the frequency with which regression or progression of disease without treatment occurred in women diagnosed with squamous cell cervical carcinoma in situ (CIS) during pregnancy. METHODS:. A retrospective chart review of all women evaluated at the University of Iowa Colposcopy C...

journal_title：Gynecologic oncology

authors： Coppola A,Sorosky J,Casper R,Anderson B,Buller RE

更新日期：1997-11-01 00:00:00

abstract：:We examined the efficacy of CA125 and urinary gonadotropin fragment (UGF) measurements for differentiating benign from malignant pelvic masses. CA125, at a cutoff of greater than or equal to 35 U/ml, detected 82% (n = 71) of ovarian malignancies, but also falsely detected 14% of (n = 332) patients with benign pelvic m...

journal_title：Gynecologic oncology

authors： Cole LA,Nam JH,Chambers JT,Schwartz PE

更新日期：1990-03-01 00:00:00

abstract：:Fifty patients with cervical cancer were treated with radical hysterectomy and lymphadenectomy followed by postoperative radiation therapy for high risk factors (nodal metastases, lymphvascular space invasion, close or involved margins) at the University of Alabama at Birmingham Medical Center from 1969 to 1984. Fifte...

journal_title：Gynecologic oncology

authors： Barter JF,Soong SJ,Shingleton HM,Hatch KD,Orr JW Jr

更新日期：1989-03-01 00:00:00

abstract：:The purpose of this study was to evaluate the serum tumor markers CYFRA 21-1 and squamous-cell carcinoma antigen (SCC) in the follow-up of squamous-cell cervical cancer patients. One hundred-ninety-three serum samples, which were collected pretherapeutically and during follow-up of 30 patients suffering from squamous-...

journal_title：Gynecologic oncology

authors： Kainz C,Sliutz G,Mustafa G,Bieglmayr C,Koelbl H,Reinthaller A,Gitsch G

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVE:We report a case of uterine leiomyosarcoma occurring after uterine artery embolization and review the previously published cases. We estimate the incidence of sarcoma after UAE, the mean diagnostic delay in young women undergoing this procedure and review the potential and limits of preoperative procedures in...

journal_title：Gynecologic oncology

authors： Papadia A,Salom EM,Fulcheri E,Ragni N

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Traditionally, hysterectomy is considered definitive therapy for cervical adenocarcinoma in situ (AIS) in women beyond childbearing. CASE:A 45-year-old gravida 2, para 2 patient presented with cervical dysplasia and on pathology review of the large loop excision procedure cervical adenocarcinoma in situ was...

journal_title：Gynecologic oncology

authors： Miller B,Dunn J,Dalrymple J,Krivak TC

更新日期：2005-11-01 00:00:00

abstract：:Eighteen (18) previously untreated patients with grade I (9) and II (9) endometrial adenocarcinoma provided endometrial samples for biochemical analysis of estrogen and progesterone receptors. The same samples were evaluated by histology and ultrastructure. Progesterone receptor negative samples (PR less than 1000 fmo...

journal_title：Gynecologic oncology

authors： Horbelt DV,Freedman RS,Roberts DK,Walker NJ,Edwards CL,Jones LA

更新日期：1984-06-01 00:00:00

abstract：:The Patient Protection and Affordable Care Act (ACA) was signed into law by President Barack Obama in 2010. While initial implementation of the law began shortly thereafter, the full implementation will take place over the next few years. With respect to cancer care, the act was intended to make care more accessible, ...

journal_title：Gynecologic oncology

authors： Duska LR,Engelhard CL

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:Our objective was to determine the rate of BRCA1/2 deficiency in platinum-sensitive and platinum-resistant tumors from a cohort of unselect patients with advanced epithelial ovarian cancer (EOH). METHODS:BRCA1/2 mutation analysis was performed in 29 patients with platinum-sensitive EOC and 24 patients with p...

journal_title：Gynecologic oncology

authors： Dann RB,DeLoia JA,Timms KM,Zorn KK,Potter J,Flake DD 2nd,Lanchbury JS,Krivak TC

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:Early detection of ovarian cancer should improve overall survival. Multiple serum markers have been evaluated as possible tests to detect early stage disease, but few urine markers have been studied. Mesothelin has been detected in serum from patients with ovarian cancer, but has not been previously reported...

journal_title：Gynecologic oncology

authors： Badgwell D,Lu Z,Cole L,Fritsche H,Atkinson EN,Somers E,Allard J,Moore RG,Lu KH,Bast RC Jr

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:To quantify the effect of race/ethnicity on risk of complete and partial molar pregnancy. METHODS:We conducted a cross-sectional study including women who were followed for complete or partial mole and those who had a live singleton birth in a teaching hospital in the northeastern United States between 2000 ...

journal_title：Gynecologic oncology

authors： Melamed A,Gockley AA,Joseph NT,Sun SY,Clapp MA,Goldstein DP,Berkowitz RS,Horowitz NS

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Neuroendocrine carcinomas (NECs) of the cervix comprise only 2% of all cervical cancers. Prospective data is limited and treatment guidelines rely on retrospective reviews and literature from lung NEC. The objective of this study was to report our experience in the management of this rare disease. METHODS:T...

journal_title：Gynecologic oncology

authors： McCann GA,Boutsicaris CE,Preston MM,Backes FJ,Eisenhauer EL,Fowler JM,Cohn DE,Copeland LJ,Salani R,O'Malley DM

更新日期：2013-04-01 00:00:00