Pyritinol hydrochloride and cognitive functions: influence on children in slow learner classes.

abstract：:Although the pathogenesis of necrotizing enterocolitis remains uncertain, ischemia appears to be an important contributing factor to the development of this disorder. Reperfusion plays a major role in ischemia-related injury, and oxygen free radicals produced during reperfusion most likely contribute to the injury. Th...

journal_title：Pediatric research

authors： Papparella A,DeLuca FG,Oyer CE,Pinar H,Stonestreet BS

更新日期：1997-08-01 00:00:00

abstract：:All-trans retinoic acid (ATRA) stimulates platelet-derived growth factor (PDGF)-A expression and enhances alveolarization in rat lungs. On d 16 of gestation, pregnant Sprague-Dawley rats were randomly assigned to either a retinoic acid group (intragastric ATRA at 10 mg/kg body weight) or a vehicle group. We punctured ...

journal_title：Pediatric research

authors： Chen CM,Chou HC,Wang LF,Lang YD,Yeh CY

更新日期：2007-11-01 00:00:00

abstract：:To determine whether epidermal growth factor (EGF) or EGF-like transforming growth factors (TGFs) are present in ovine fetal tissues, we have tested acid-ethanol extracts of ovine fetal kidney for the ability to induce anchorage-independent growth of normal rat kidney fibroblasts in soft agar and to compete with 125I-...

journal_title：Pediatric research

authors： Freemark M,Comer M

更新日期：1987-11-01 00:00:00

abstract：:In spontaneously breathing newborn lambs, alveolar hypoxia increases lung microvascular pressure, which causes lung lymph flow to increase and the concentration of protein in lymph to decrease. To see if this response derives from hypoxia itself rather than from the change in breathing pattern that occurs during hypox...

journal_title：Pediatric research

authors： Hansen TN,Haberkern CM,Hazinski TA,Bland RD

更新日期：1984-05-01 00:00:00

abstract：:Whether severe hypoglycemia alone or in combination with hyperketonemia might cause deterioration of cardiac function has been controversial. Therefore, the influence of acute hypoglycemia (mean 33 mg/dL) with and without hyperketonemia (mean 1.3 and 3.3 mM) on cardiac function, substrate utilization, and myocardial h...

journal_title：Pediatric research

authors： Breuer J,Chung KJ,Pesonen E,Haas RH,Guth BD,Sahn DJ,Hesselink JR

更新日期：1989-12-01 00:00:00

abstract：:Fetal growth restriction (FGR) remains a cause of perinatal brain injury, sometimes leading to neurological and intellectual impairment. Although the mechanisms and pathophysiology of CNS injuries have not been elucidated completely, it is possible carbohydrate and energy metabolism may have an important role in the F...

journal_title：Pediatric research

authors： Hayakawa M,Sato Y,Hattori T,Ichinohashi Y,Nakayama A,Yamamoto H,Hemmi H,Ito M,Ieda K,Kojima S

更新日期：2011-07-01 00:00:00

abstract：:Disorders affecting fetal growth are commonly associated with premature birth. IGFs and their binding proteins (IGFBPs) are potent regulators of fetal growth. In vitro evidence suggests that they regulate collagen turnover. Collagen turnover can be monitored by serum markers of type I collagen synthesis (PINP) and deg...

journal_title：Pediatric research

authors： Kajantie E,Hytinantti T,Koistinen R,Risteli J,Rutanen EM,Seppälä M,Andersson S

更新日期：2001-04-01 00:00:00

abstract：:Growth hormone (GH) regulates growth and development in the postnatal period but lacks somatotropic activity in the fetus. In contrast, the placental hormone placental lactogen (PL) stimulates amino acid transport, DNA synthesis, and somatomedin production in isolated fetal tissues, suggesting that PL may function as ...

journal_title：Pediatric research

authors： Fowlkes J,Freemark M

更新日期：1992-08-01 00:00:00

abstract：:Uteroplacental insufficiency alters the anabolic metabolism of the fetus, resulting in intrauterine growth retardation (IUGR). The metabolic and physiologic factors that cause IUGR have long standing consequences after birth. Postnatal growth and glucose metabolism are altered in the IUGR infant. Skeletal muscle is an...

journal_title：Pediatric research

authors： Lane RH,Chandorkar AK,Flozak AS,Simmons RA

更新日期：1998-05-01 00:00:00

abstract：:Treatment with phototherapy or with the lipase inhibitor orlistat decreases plasma unconjugated bilirubin (UCB) concentrations in hyperbilirubinemic Gunn rats. We investigated the mechanism(s) underlying the effects of orlistat, phototherapy, and combined treatment, using steady-state 3H-UCB kinetics. After three week...

journal_title：Pediatric research

authors： Hafkamp AM,Havinga R,Ostrow JD,Tiribelli C,Pascolo L,Sinaasappel M,Verkade HJ

更新日期：2006-04-01 00:00:00

abstract：:We measured body composition, basal metabolic rate (BMR), and total energy expenditure in 28 nonobese and 35 obese adolescents aged 12-18 y using indirect calorimetry and the doubly labeled water method. BMR was highly correlated with fat-free mass in both the nonobese and obese groups (r = 0.77 and 0.84, respectively...

journal_title：Pediatric research

authors： Bandini LG,Schoeller DA,Dietz WH

更新日期：1990-02-01 00:00:00

abstract：:Energy and nitrogen balances were measured in growing low birthweight infants fed either mother's expressed breast milk or a 20 kcal per ounce formula to determine whether or not there were differences between the two dietary groups in (1) the partition of energy among excretion, expenditure, and storage and (2) the r...

journal_title：Pediatric research

authors： Whyte RK,Haslam R,Vlainic C,Shannon S,Samulski K,Campbell D,Bayley HS,Sinclair JC

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:Diseases of adulthood, such as diabetes and hypertension, may be related to changes during pregnancy, particularly in kidney. We hypothesized that acute kidney injury progresses more rapidly in cases of fetal programming. METHODS:Diabetic dams' offspring were divided into: CC (controls, receiving vehicle); ...

journal_title：Pediatric research

authors： Corrêa RR,Pucci KR,Rocha LP,Pereira Júnior CD,Helmo FR,Machado JR,Rocha LB,Rodrigues AR,Glória MA,Guimarães CS,Câmara NO,Reis MA

更新日期：2015-03-01 00:00:00

abstract：:Epidermal growth factor (EGF) and transforming growth factor-alpha (TGF-alpha) are mitogenic to the intestinal epithelium. To further clarify their role in the developing human fetal gut, their expression was studied in fetuses at 15 to 20 wk of gestation. TGF-alpha mRNA was present throughout the gastrointestinal tra...

journal_title：Pediatric research

authors： Miettinen PJ

更新日期：1993-05-01 00:00:00

abstract：:Several epithelial ion transporters are developmentally regulated in the preweaning period, at the time when the circulating levels of glucocorticoid and mineralocorticoid hormones increase. The specific role of glucocorticoids and mineralocorticoids in the maturation of epithelial ion transport is still disputed. In ...

journal_title：Pediatric research

authors： Wang ZM,Yasui M,Celsi G

更新日期：1995-08-01 00:00:00

abstract：:Chronically catheterized fetal lambs (n = 11, gestational age 111-139 days) and neonatal lambs (n = 20, postnatal age 4-30 days) were studied to explore during development the relationship of renal hemodynamic responses during hypoxemia to plasma epinephrine concentration (E), plasma norepinephrine concentration (NE),...

journal_title：Pediatric research

authors： Weismann DN,Robillard JE

更新日期：1988-02-01 00:00:00

abstract：:Altered transfer of nutrients from mother to conceptus may be involved in the pathogenesis of the developmental disturbances in offspring of diabetic mothers. In our study, the embryonic uptake of a saturated (palmitic acid) and a nonsaturated (arachidonic acid) fatty acid was evaluated in a normal and a diabetes-like...

journal_title：Pediatric research

authors： Engström E,Haglund A,Eriksson UJ

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Encephalopathic neonates undergoing therapeutic hypothermia have increased risk for coagulopathy secondary to perinatal asphyxia and effects of cooling on the coagulation enzyme cascade. Thromboelastography (TEG) allows for a comprehensive assessment of coagulation that can be regulated for temperature. TEG ...

journal_title：Pediatric research

authors： Forman KR,Wong E,Gallagher M,McCarter R,Luban NL,Massaro AN

更新日期：2014-05-01 00:00:00

abstract：:Mesenchymal stem cell (MSC) transplantation represents the next breakthrough in the treatment of currently intractable and devastating neonatal disorders with complex multifactorial etiologies, including bronchopulmonary dysplasia, hypoxic ischemic encephalopathy, and intraventricular hemorrhage. Absent engraftment an...

journal_title：Pediatric research

authors： Park WS,Ahn SY,Sung SI,Ahn JY,Chang YS

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Following our clinical observation of tonic responses in response to the knee jerk in infants at very high risk for cerebral palsy (VHR infants), we systematically studied tonic responses, clonus, and reflex irradiation. We questioned (i) whether these responses occurred more often in VHR infants than in typ...

journal_title：Pediatric research

authors： Hamer EG,Dijkstra LJ,Hooijsma SJ,Zijdewind I,Hadders-Algra M

更新日期：2016-09-01 00:00:00

abstract：:Respiratory distress syndrome (RDS) due to surfactant deficiency is the most common cause of respiratory failure in preterm infants. Tremendous progress has been made since the original description that surfactant deficiency is the major cause of RDS. Surfactant therapy has been extensively studied in preterm infants ...

journal_title：Pediatric research

authors： Sardesai S,Biniwale M,Wertheimer F,Garingo A,Ramanathan R

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:In Celiac disease (CD), cytoskeletal integrity of intestinal cells is disrupted by gliadin exposure. This study investigates the role of heat shock protein (Hsp)70 during cytoskeletal recovery in CD by assessing its induction and effects on junctional proteins. METHODS:Using an in-vitro model of CD, cytoske...

journal_title：Pediatric research

authors： Bidmon-Fliegenschnee B,Lederhuber HCh,Csaicsich D,Pichler J,Herzog R,Memaran-Dadgar N,Huber WD,Aufricht C,Kratochwill K

更新日期：2015-10-01 00:00:00

abstract：:The objective was to investigate any possible relationship between functional and structural vascular changes in women with low gestational age and/or low birth weight by analyzing the retinal vascular pattern in women with thoroughly documented blood pressure. Retinal vessel morphology was evaluated by digital image ...

journal_title：Pediatric research

authors： Kistner A,Jacobson L,Jacobson SH,Svensson E,Hellstrom A

更新日期：2002-06-01 00:00:00

abstract：:The development of amniotic fluid turbidity during the third trimester is a known marker of fetal lung maturity. We hypothesized that this turbidity results from detachment of vernix caseosa from the fetal skin secondary to interaction with pulmonary-derived phospholipids in the amniotic fluid. To test this hypothesis...

journal_title：Pediatric research

authors： Narendran V,Wickett RR,Pickens WL,Hoath SB

更新日期：2000-07-01 00:00:00

abstract：:Momentum around the era of genomic medicine is building, and with it, anticipation of the benefits that whole genome analysis (personalized or individualized genomics) will bring for the provision of health care. These technologies have the potential to revolutionize genetic diagnosis; however, the expansive data gene...

journal_title：Pediatric research

authors： Ali-Khan SE,Daar AS,Shuman C,Ray PN,Scherer SW

更新日期：2009-10-01 00:00:00

abstract：:Nitric Oxide (NO) can be cytotoxic or cytoprotective depending on amount and location of its generation. eNOS is important in modulating blood flow and is allosterically regulated. Inducible NOS (iNOS) tends to produce large quantities of NO leading to cell injury. We studied the role and regulation of NOS in carbon t...

journal_title：Pediatric research

authors： Liu H,Subramony C,Nowicki M

更新日期：2008-06-01 00:00:00

abstract：:Acute kidney injury (AKI) is common in premature infants and is associated with poor outcomes. Novel biomarkers can detect AKI promptly. Because premature infants are born with underdeveloped kidneys, baseline biomarker values may differ. We describe baseline values of urinary neutrophil gelatinase-associated lipocali...

journal_title：Pediatric research

authors： Askenazi DJ,Koralkar R,Levitan EB,Goldstein SL,Devarajan P,Khandrika S,Mehta RL,Ambalavanan N

更新日期：2011-09-01 00:00:00

abstract：:Blood volume (BV), red cell mass (RCM; Cr-51) and plasma volume (125I-labeled albumin) were measured in 205 piglets from 28 litters shortly after birth. Spontaneous cord rupture in healthy piglets occurred during delivery (n = 25) or within 190 sec of birth (n = 82). Spontaneous and induced delay of cord rupture resul...

journal_title：Pediatric research

authors： Linderkamp O,Betke K,Güntner M,Jap GH,Riegel KP,Walser K

更新日期：1981-01-01 00:00:00

abstract：:A technique is described in which paper chromatoelectrophoresis is used to measure the bilirubin binding capacity of albumin in serum. It is equivalent to the Sephadex G-25 method and its results are highly reproducible. From a single pool of serum, multiple determinations indicated the mean bilirubin binding capacity...

journal_title：Pediatric research

authors： Ainbender E,Brown EG,Lee YJ,Sweet AY

更新日期：1977-07-01 00:00:00

abstract：:BackgroundSotos syndrome (SoS) is an overgrowth disorder with various congenital anomalies and is usually accompanied by other clinical problems. However, anorectal malformations have not been documented as part of the SoS entity. Our objective is to report on a case of SoS associated with Hirschsprung's disease (HSCR...

journal_title：Pediatric research

authors： Sio CA,Jung K,Kim JH,Cheong HS,Shin E,Jang H,Yoon M,Jang H,Shin HD

更新日期：2017-07-01 00:00:00