Noninvasive evaluation of intrarenal oxygenation with BOLD MRI.

abstract：BACKGROUND:There are few data regarding medium-term outcome of coronary artery bypass grafting (CABG) in patients with severe left ventricular (LV) systolic dysfunction, particularly in the modern era, and even less assessing preoperative factors that might identify patients at highest risk. METHODS AND RESULTS:Three ...

journal_title：Circulation

authors： Hillis GS,Zehr KJ,Williams AW,Schaff HV,Orzulak TA,Daly RC,Mullany CJ,Rodeheffer RJ,Oh JK

更新日期：2006-07-04 00:00:00

abstract：BACKGROUND:Population screening for abdominal aortic aneurysm (AAA) has commenced in several countries, and has been shown to reduce AAA-related mortality by up to 50%. Most men who screen positive have an AAA <5.5 cm in diameter, the referral threshold for treatment, and are entered into an ultrasound surveillance pro...

journal_title：Circulation

authors： Oliver-Williams C,Sweeting MJ,Jacomelli J,Summers L,Stevenson A,Lees T,Earnshaw JJ

更新日期：2019-03-12 00:00:00

abstract：BACKGROUND:The regulation of the cardiac neutral endopeptidase (EC 24.10, NEP) that degrades bradykinin and natriuretic peptides has been investigated in human cardiac hypertrophy and heart failure. Methods and Results- NEP mRNA was quantitated by real-time polymerase chain reaction (PCR) in left ventricular biopsies f...

journal_title：Circulation

authors： Fielitz J,Dendorfer A,Pregla R,Ehler E,Zurbrügg HR,Bartunek J,Hetzer R,Regitz-Zagrosek V

更新日期：2002-01-22 00:00:00

abstract：BACKGROUND:A complete understanding of fluid mechanics in Fontan physiology includes knowledge of the caval contributions to right (RPA) and left (LPA) pulmonary arterial blood flow, total systemic venous return, and relative blood flow to each lung. METHODS AND RESULTS:Ten Fontan patients underwent cine MRI. Three ci...

journal_title：Circulation

authors： Fogel MA,Weinberg PM,Rychik J,Hubbard A,Jacobs M,Spray TL,Haselgrove J

更新日期：1999-03-09 00:00:00

abstract：BACKGROUND:Smooth muscle cells (SMCs) play a key role in intimal thickening in atherosclerosis and restenosis. The precise signaling pathways by which the proliferation of SMCs is regulated are largely unknown. The TR3 orphan receptor, the mitogen-induced nuclear orphan receptor (MINOR), and the nuclear receptor of T c...

journal_title：Circulation

authors： Arkenbout EK,de Waard V,van Bragt M,van Achterberg TA,Grimbergen JM,Pichon B,Pannekoek H,de Vries CJ

更新日期：2002-09-17 00:00:00

abstract：:Purine compounds modulate sympathetic neurotransmission; this modulation decreases nervous discharge by stimulating presynaptic inhibitory adenosine receptors, an effect antagonized by theophylline, and causes vasoconstriction through the stimulation of postsynaptic ATP receptors. In humans we evaluated the effect of ...

journal_title：Circulation

authors： Taddei S,Pedrinelli R,Salvetti A

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Coronary sinus access by electrode catheters is easier in patients with atrioventricular junctional reentry tachycardia (AVJRT) than in patients with other supraventricular tachyarrhythmias. The reason for this has not been addressed. METHODS AND RESULTS:The size and shape of the proximal coronary sinus wer...

journal_title：Circulation

authors： Doig JC,Saito J,Harris L,Downar E

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:To simplify extensive primary repair of the thoracic aorta in acute type A aortic dissection, we developed the open triple-branched stent graft placement technique. The early results of this new technique are reported. METHODS AND RESULTS:Between June 2008 and November 2009, 30 patients with acute Stanford ...

journal_title：Circulation

authors： Chen LW,Dai XF,Lu L,Zhang GC,Cao H

更新日期：2010-10-05 00:00:00

abstract：BACKGROUND:Electrophysiological mechanisms by which adenosine may activate cardiac afferent neurons are unknown. Slow afterhyperpolarizations (AHPs) follow action potentials in a subset of vagal C afferents, rendering them inexcitable. The purpose of this study was to test the hypothesis that adenosine increases vagal ...

journal_title：Circulation

authors： Middlekauff HR,Doering A,Weiss JN

更新日期：2001-03-06 00:00:00

abstract：BACKGROUND:Angiotensin (Ang) II type 1 receptor (AT1-R) induces cardiomyocyte hypertrophy and fibroblast proliferation, whereas the physiological role of AT2-R in cardiac remodeling remains poorly defined. METHODS AND RESULTS:Using Bio14.6 cardiomyopathic (CM) hamsters, we found that AT2-R sites were increased by 153%...

journal_title：Circulation

authors： Ohkubo N,Matsubara H,Nozawa Y,Mori Y,Murasawa S,Kijima K,Maruyama K,Masaki H,Tsutumi Y,Shibazaki Y,Iwasaka T,Inada M

更新日期：1997-12-02 00:00:00

abstract：BACKGROUND:Observational studies have identified an association between body mass index (BMI) and incident atrial fibrillation (AF). Inferring causality from observational studies, however, is subject to residual confounding, reverse causation, and bias. The primary objective of this study was to evaluate the causal as...

journal_title：Circulation

authors： Chatterjee NA,Giulianini F,Geelhoed B,Lunetta KL,Misialek JR,Niemeijer MN,Rienstra M,Rose LM,Smith AV,Arking DE,Ellinor PT,Heeringa J,Lin H,Lubitz SA,Soliman EZ,Verweij N,Alonso A,Benjamin EJ,Gudnason V,Stricker BHC

更新日期：2017-02-21 00:00:00

abstract：BACKGROUND:Unlike skeletal myocytes, mammalian adult cardiomyocytes cannot regenerate after injury. A possible strategy to increase viability and augment ventricular function after myocardial injury is fetal myocardial tissue transplantation. The engrafted fetal cells are a potential source of growth factors and can be...

journal_title：Circulation

authors： Leor J,Patterson M,Quinones MJ,Kedes LH,Kloner RA

更新日期：1996-11-01 00:00:00

abstract：:Children with congenital aortic stenosis have "excessive" left ventricular hypertrophy with reduced resting systolic wall stress that allows for supernormal ejection performance. If aortic stenosis is uncorrected, this pattern persists until adulthood. The effect of removing the aortic pressure gradient on left ventri...

journal_title：Circulation

authors： Dorn GW 2nd,Donner R,Assey ME,Spann JF Jr,Wiles HB,Carabello BA

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Retinol-binding protein 4 (RBP4) may play an important role in the origin of insulin resistance and metabolic syndrome. Few prospective data are available on the relationship between RBP4 and coronary heart disease (CHD). Furthermore, previous studies did not distinguish among full-length and truncated forms...

journal_title：Circulation

authors： Sun Q,Kiernan UA,Shi L,Phillips DA,Kahn BB,Hu FB,Manson JE,Albert CM,Rexrode KM

更新日期：2013-05-14 00:00:00

abstract：BACKGROUND:The outcome of patients with corrected transposition of the great arteries (CTGA) is variably affected by associated intracardiac defects, tricuspid valve competence, and systemic right ventricular (RV) function. The relative importance of these factors in long-term outcome has not been evaluated. METHODS A...

journal_title：Circulation

authors： Prieto LR,Hordof AJ,Secic M,Rosenbaum MS,Gersony WM

更新日期：1998-09-08 00:00:00

abstract：BACKGROUND:Isomerism is associated with a complex spectrum of anomalies. There is paucity of data on prenatally detected cases. METHODS AND RESULTS:Between January 1990 and February 2004, 83 of 166 cases (50%) had a prenatal diagnosis of left isomerism (LAI; 52 of 97) or right isomerism (RAI; 31 of 69) at our institut...

journal_title：Circulation

authors： Lim JS,McCrindle BW,Smallhorn JF,Golding F,Caldarone CA,Taketazu M,Jaeggi ET

更新日期：2005-10-18 00:00:00

abstract：:Few data are available regarding the effects of exercise training upon cardiac structure and performance in man. We evaluated the echograms of 24 normals before (PRE) and after (POST) 11 weeks of endurance exercise training. Conditioning consisted of a walk-jog-run protocol at 70% maximal heart rate for one hour four ...

journal_title：Circulation

authors： DeMaria AN,Neumann A,Lee G,Fowler W,Mason DT

更新日期：1978-02-01 00:00:00

abstract：:Intermittent aortic root infusion of a cold solution containing either potassium chloride (KCl) or diltiazem was performed in 32 dogs during a 2-hour aortic clamping. Half of the dogs in each group had a critical stenosis created on the circumflex artery before cardiopulmonary bypass. Global left ventricular (LV) func...

journal_title：Circulation

authors： Vouhé PR,Hélias J,Robert P,Grondin CM

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Vascular inflammation and subsequent matrix degradation play an important role in the development of atherosclerosis. We previously reported that adiponectin, an adipose-specific plasma protein, accumulated to the injured artery and attenuated vascular inflammatory response. Clinically, high plasma adiponect...

journal_title：Circulation

authors： Kumada M,Kihara S,Ouchi N,Kobayashi H,Okamoto Y,Ohashi K,Maeda K,Nagaretani H,Kishida K,Maeda N,Nagasawa A,Funahashi T,Matsuzawa Y

更新日期：2004-05-04 00:00:00

abstract：BACKGROUND:The risk of syncope occurring while driving has obvious implications for personal and public safety. We aimed to define the clinical characteristics, causes, and prognosis of syncope while driving. METHODS AND RESULTS:In this case-control study of consecutive patients evaluated for syncope from 1996 through...

journal_title：Circulation

authors： Sorajja D,Nesbitt GC,Hodge DO,Low PA,Hammill SC,Gersh BJ,Shen WK

更新日期：2009-09-15 00:00:00

abstract：:Resting hemodynamics improve during vasodilator administration in patients, with congestive heart failure (CHF), but the effects of these agents on exercise is unknown. Twenty-two patients with class II or III CHF performed bicycle exercise to symptomatic maximum before and 90 minutes after random double-blind adminis...

journal_title：Circulation

authors： Franciosa JA,Cohn JN

更新日期：1979-06-01 00:00:00

abstract：:The significance of the direction of the ST-segment shifts on the 12-lead electrocardiogram was evaluated in 82 consecutive patients with unstable angina. Eighteen patients with ST-segment elevation (group I) were compared with 64 patients with ST-segment depression (group II). There was no difference between group I ...

journal_title：Circulation

authors： Plotnick GD,Conti CR

更新日期：1975-06-01 00:00:00

abstract：:We evaluated the effects of selective activation of H1 receptors on coronary hemodynamics in 16 patients divided into two groups: group A, 11 patients with atypical angina or valvular heart disease and normal coronary arteries, and group B, five patients with spontaneous angina, four of whom had significant (greater t...

journal_title：Circulation

authors： Vigorito C,Poto S,Picotti GB,Triggiani M,Marone G

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Adults with obesity or type 2 diabetes mellitus (T2DM) are at higher risk for stroke and myocardial infarction. Increased carotid intima-media thickness (cIMT) and stiffness are associated with these adverse outcomes. We compared carotid arteries in youth who were lean, were obese, or had T2DM. METHODS AND ...

journal_title：Circulation

authors： Urbina EM,Kimball TR,McCoy CE,Khoury PR,Daniels SR,Dolan LM

更新日期：2009-06-09 00:00:00

abstract：BACKGROUND:Cholesterol-lowering therapy can improve cardiovascular morbidity and mortality in patients with atherosclerosis. Although the mechanisms responsible are unclear, these benefits precede macroscopic changes in the vasculature. Emerging evidence that improvement in endothelial function may occur requires subst...

journal_title：Circulation

authors： O'Driscoll G,Green D,Taylor RR

更新日期：1997-03-04 00:00:00

abstract：:Successful long-term myocardial preservation is dependent on optimizing conditions during arrest, storage, and reperfusion. Neonatal piglet hearts were arrested and stored in University of Wisconsin solution (UW) at 4 degrees C for 24 hours and reperfused on a blood-perfused, adult animal-supported isolated circuit. R...

journal_title：Circulation

authors： Stein DG,Permut LC,Drinkwater DC Jr,Bhuta S,Chang P,Wu A,Laks H

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Recent findings suggesting the involvement of adventitial cells in coronary repair have raised questions regarding the phenotypic "plasticity" of medial smooth muscle cells (SMCs). Accordingly, the aims of the present study were to examine the characteristics of coronary medial and adventitial cells and to c...

journal_title：Circulation

authors： Patel S,Shi Y,Niculescu R,Chung EH,Martin JL,Zalewski A

更新日期：2000-02-08 00:00:00

abstract：:Normal right ventricular muscles and similar preparations obtained from cats with signs of subacute right ventricular failure (RVF) (3 to 14 days after pressure overload induced by pulmonary artery coarctation) were studied during stimulation (at 0.5 Hz) and exposure to high-K+ Tyrode's solution. Twitch force, rate of...

journal_title：Circulation

authors： Gaide MS,Kimura S,Lodge NJ,Cameron JS,Kozlovskis PL,Myerburg RJ,Bassett AL

更新日期：1986-03-01 00:00:00

abstract：:Recent molecular studies have suggested that viral myocarditis frequently underlies human congestive cardiomyopathy; however, only moderately sensitive and specific techniques were used. Polymerase chain reaction (PCR) gene amplification is a sensitive, specific technique ideally suited for the diagnosis of viral dise...

journal_title：Circulation

authors： Jin O,Sole MJ,Butany JW,Chia WK,McLaughlin PR,Liu P,Liew CC

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Endothelin-converting enzyme (ECE)-1 activates endothelin-1 (ET-1) and may thus contribute to the regulation of vascular tone and cell growth during atherosclerosis. METHODS AND RESULTS:To evaluate ECE-1 immunoreactivity concerning big ET-1/ET-1, we performed qualitative and quantitative immunohistochemistr...

journal_title：Circulation

authors： Ihling C,Szombathy T,Bohrmann B,Brockhaus M,Schaefer HE,Loeffler BM

更新日期：2001-08-21 00:00:00