Abstract：
:A prospective double-blind study was performed in which 30 adult patients with recurrent urinary tract infections due to Escherichia coli, and Proteus mirabilis organisms were treated by twenty-eight-day courses of either ampicillin, 500 mg. four times a day, or trimethoprim-sulphamethoxazole, 2 tablets twice a day. In terms of freedom from infection fifty-six days after the cessation of treatment in both complicated and uncomplicated infections, trimethoprim-sulphamethoxazole yielded results superior to those of ampicillin. In comparing the results of this study with those of a similar study in which the same agents were given for ten-day courses it appears that only in the complicated infection is there an advantage in giving a prolonged course of trimethoprim-sulphamethoxazole. This study did not generate any evidence to support the extension of ampicillin therapy for urinary tract infection beyond ten days.
journal_name
Urologyjournal_title
Urologyauthors
Cosgrove MD,Gault C,Fiorentino N,Ivler Ddoi
10.1016/0090-4295(76)90302-2subject
Has Abstractpub_date
1976-02-01 00:00:00pages
156-9issue
2eissn
0090-4295issn
1527-9995journal_volume
7pub_type
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