Nutritional factors and vertical transmission of HIV-1. Epidemiology and potential mechanisms.

abstract：:High concentrations of glucose induce insulin resistance and impair insulin secretion in a manner that mirrors type 2 diabetes, a phenomenon known as glucose toxicity. High concentrations of hexosamines mimic these effects, leading to the hypothesis that cells use hexosamine flux as a glucose- and satiety-sensing path...

journal_title：Annals of the New York Academy of Sciences

authors： Cooksey RC,McClain DA

更新日期：2002-06-01 00:00:00

abstract：:Experimental evidence confirms that the matrix metalloproteinases (MMPs) play a fundamental role in a wide variety of pathologic conditions that involve connective tissue destruction including osteoarthritis and rheumatoid arthritis, tumor metastasis and angiogenesis, corneal ulceration, multiple sclerosis, periodonta...

journal_title：Annals of the New York Academy of Sciences

authors： Skotnicki JS,Zask A,Nelson FC,Albright JD,Levin JI

更新日期：1999-06-30 00:00:00

abstract：:"Vascular anomalies" represents a spectrum of vascular lesions, of unclear etiology and often with unpredictable behavior. Patients with vascular anomalies represent a unique population, in that they have focal aberrations of vascular development (in vascular malformations) or vascular proliferation (in hemangiomas). ...

journal_title：Annals of the New York Academy of Sciences

authors： Blei F

更新日期：2008-01-01 00:00:00

abstract：:Enhanced levels of plasminogen activator inhibitor-1 (PAI-1) are considered to be a risk factor for pathological conditions associated with hypoxia or hyperinsulinemia. The expression of the PAI-1 gene is increased by insulin in different cells, although, the molecular mechanisms behind insulin-induced PAI-1 expressio...

journal_title：Annals of the New York Academy of Sciences

authors： Dimova EY,Kietzmann T

更新日期：2006-12-01 00:00:00

abstract：:Accelerated atherosclerosis occurs in patients with type III hyperlipoproteinemia and familial hypercholesterolemia. These genetic disorders focus attention on specific types of lipoproteins as being responsible for the development of accelerated coronary artery heart disease. The accumulation of chylomicron remnants ...

journal_title：Annals of the New York Academy of Sciences

authors： Weisgraber KH,Innerarity TL,Rall SC Jr,Mahley RW

更新日期：1990-01-01 00:00:00

abstract：:Inflammasomes continue to generate interest in an increasing number of disciplines owing to their unique ability to integrate a myriad of signals from pathogen- and damage-associated molecular patterns into a proinflammatory response. This potent caspase-1-dependent process is capable of activating the innate immune s...

journal_title：Annals of the New York Academy of Sciences

authors： Sutterwala FS,Haasken S,Cassel SL

更新日期：2014-06-01 00:00:00

abstract：:Mouse models with targeted deletion of the genes encoding the enzyme 25-hydroxyvitamin D 1alpha-hydroxylase [1alpha(OH)ase], and the vitamin D receptor (VDR), have provided considerable insight into the regulation of mineral and skeletal physiology by 1,25-dihydroxyvitamin D [1,25(OH)(2)D]. Dietary manipulation induce...

journal_title：Annals of the New York Academy of Sciences

authors： Goltzman D

更新日期：2010-03-01 00:00:00

abstract：:This article focuses on the importance of social engagement and the behavioral and neurophysiological mechanisms that allow individuals to reduce psychological and physical distance. A model of social engagement derived from the Polyvagal Theory is presented. The model emphasizes phylogeny as an organizing principle a...

journal_title：Annals of the New York Academy of Sciences

authors： Porges SW

更新日期：2003-12-01 00:00:00

abstract：:Macrolide and polyether biosynthesis in actinomycetes is regulated at the level of precursor supply by effects of nutrients on the sources of the low-molecular-weight fatty acids used to build the carbon framework of these antibiotics. Ammonium ion appears to suppress the first enzymes of valine and threonine cataboli...

journal_title：Annals of the New York Academy of Sciences

authors： Tang L,Zhang YX,Hutchinson CR

更新日期：1994-05-02 00:00:00

abstract：:Human germ-cell tumors (GCTs) are a heterogeneous group of neoplasms. Based on epidemiology, anatomical site of presentation, histology, chromosomal constitution, and pattern of genomic imprinting, GCTs are classified into five entities. Within the testis, three types of GCTs can be diagnosed: type I (teratomas and yo...

journal_title：Annals of the New York Academy of Sciences

authors： Looijenga LH,Gillis AJ,Stoop HJ,Hersmus R,Oosterhuis JW

更新日期：2007-12-01 00:00:00

abstract：:The therapeutic value of thymectomy for myasthenia is still questioned although it retains an important place among management modalities that strive for sustained remission. Questions derive from uncertainty as to appropriate timing, variable extent of resection and quantitation of response. Forty-seven patients, fol...

journal_title：Annals of the New York Academy of Sciences

authors： Penn AS,Jaretzki A 3rd,Wolff M,Chang HW,Tennyson V

更新日期：1981-01-01 00:00:00

abstract：:Clinical trials for ischemic stroke have been characterized by a disappointing series of negative results, using a panoply of pharmacologic agents. This paper emphasizes five physiologic measures that can be taken to mitigate ischemic brain damage. These are (1) hypothermia, (2) insulin, (3) arterial hyperoxemia, (4) ...

journal_title：Annals of the New York Academy of Sciences

authors： Auer RN

更新日期：2001-06-01 00:00:00

abstract：:A cross-sectional study of raw meat samples from the local meat market of Kathmandu Metropolitan City was carried out during September 2002 to May 2003 with special emphasis on isolation and identification of Salmonella bacteria. A total of 123 raw meat samples (55 chicken, 37 buffalo, and 31 goat) were collected and ...

journal_title：Annals of the New York Academy of Sciences

authors： Maharjan M,Joshi V,Joshi DD,Manandhar P

更新日期：2006-10-01 00:00:00

abstract：:In the pancreatic islets, pituitary adenylate cyclase-activating polypeptide (PACAP) is expressed in beta cells and autonomic nerve terminals; the majority of these nerve terminals are parasympathetic. PACAP binds to three types of G protein-coupled receptors (GPCRs): VPAC1 receptors, VPAC2 receptors, and PAC1 recepto...

journal_title：Annals of the New York Academy of Sciences

authors： Ahrén B

更新日期：2008-11-01 00:00:00

abstract：:Tazobactam was the most recent β-lactamase inhibitor to be approved in 1993. Since the approval of piperacillin-tazobactam, the complexity of β-lactamase-mediated resistance among Gram-negative bacilli has increased enormously. After more than 20 years since the first such combination, amoxicillin-clavulanic acid, was...

journal_title：Annals of the New York Academy of Sciences

authors： Shlaes DM

更新日期：2013-01-01 00:00:00

abstract：:Music-supported therapy (MST) has been developed recently to improve the use of the affected upper extremity after stroke. MST uses musical instruments, an electronic piano and an electronic drum set emitting piano sounds, to retrain fine and gross movements of the paretic upper extremity. In this paper, we first desc...

journal_title：Annals of the New York Academy of Sciences

authors： Rodriguez-Fornells A,Rojo N,Amengual JL,Ripollés P,Altenmüller E,Münte TF

更新日期：2012-04-01 00:00:00

abstract：:It is well established for both rat and man that the total testosterone concentration within the testis is far higher than that in serum. We know for the rat that intratesticular testosterone can be reduced by 50-60% without an adverse effect on spermatogenesis but that the required intratesticular testosterone concen...

journal_title：Annals of the New York Academy of Sciences

authors： Jarow JP,Zirkin BR

更新日期：2005-12-01 00:00:00

abstract：:The role of dopaminergic activity in susceptibility of methamphetamine (MAP) psychosis (flashbacks) to subsequent spontaneous recurrences was studied. Plasma monoamine metabolite levels were assayed in 23 flashbackers, of whom 10 experienced a single flashback, 8 exhibited subsequent flashbacks and 5 with the last epi...

journal_title：Annals of the New York Academy of Sciences

authors： Yui K,Goto K,Ikemoto S

更新日期：2004-10-01 00:00:00

abstract：:Advances in resuscitation science have indicated that, contrary to perception, death by cardiorespiratory criteria can no longer be considered a specific moment but rather a potentially reversible process that occurs after any severe illness or accident causes the heart, lungs, and brain to stop functioning. The resul...

journal_title：Annals of the New York Academy of Sciences

authors： Parnia S

更新日期：2014-11-01 00:00:00

abstract：:Continuous dopamine (DA) stimulation is a therapeutic approach that applies to the treatment of motor fluctuations due to pulsatile DA stimulation in Parkinson's disease (PD), to cure the abuse of drugs, such as cocaine or amphetamine (which produce short-lasting peaks of extracellular DA), and as a safe therapeutic a...

journal_title：Annals of the New York Academy of Sciences

authors： Biagioni F,Busceti CL,Molinaro G,Battaglia G,Giorgi FS,Ruggieri S,Fornai F

更新日期：2006-08-01 00:00:00

abstract：:Mast cells located in connective tissues are a potent source of vasoactive and inflammatory mediators, such as cytokines. They accumulate in tissues in a wide variety of diseases where their function in most cases in unclear. In this report we provide evidence that rat basophilic leukemia cells (RBLC) cultured with a ...

journal_title：Annals of the New York Academy of Sciences

authors： Conti P,Barbacane RC,Trakatellis M,Placido FC,Cataldo I,Reale M

更新日期：1997-12-15 00:00:00

abstract：:This paper discusses experimental research aimed at defining a base drag reduction device based on splitter plates. The unsteady three-dimensional nature of the flow is studied by Schlieren photography, particle image velocimetry, and measurement of the total unsteady lift and drag loads. ...

journal_title：Annals of the New York Academy of Sciences

authors： Neau L,Pruvost J,Rodriguez O,Loc TP

更新日期：2002-10-01 00:00:00

abstract：:Previous studies in postmenopausal women have reported that estrogen treatment (ET) modulates the risk for developing Alzheimer's disease (AD). It has recently been hypothesized that there may be a "critical period" around the time of menopause during which the prescription of ET may reduce the risk of developing AD i...

journal_title：Annals of the New York Academy of Sciences

authors： Craig MC,Murphy DG

更新日期：2010-09-01 00:00:00

abstract：:The impact of climate change on biodiversity is now evident, with the direct impacts of changing temperature and rainfall patterns and increases in the magnitude and frequency of extreme events on species distribution, populations, and overall ecosystem function being increasingly publicized. Changes in the climate sy...

journal_title：Annals of the New York Academy of Sciences

authors： Maxwell SL,Venter O,Jones KR,Watson JE

更新日期：2015-10-01 00:00:00

abstract：:Disorientation may draw attention from other activities and its impact on cognition may cause pilot error and problems of concentration in dizzy patients. Tasks used to study the impact of disorientation include number processing, intelligence scales and Brookes matrices (reproduction of 2xD patterns of numbers vs. no...

journal_title：Annals of the New York Academy of Sciences

authors： Gresty MA,Golding JF

更新日期：2009-05-01 00:00:00

abstract：:Several reports addressed the issue of how the alternative splicing of exon 7 and 8 in the APP pre-mRNA is regulated in different tissues. Of special interest here was the potential involvement of exon 7 containing APP splice isoforms, since this exon codes for a serine protease inhibitor and is therefore of putative ...

journal_title：Annals of the New York Academy of Sciences

authors： Sandbrink R,Banati R,Masters CL,Beyreuther K,König G

更新日期：1993-09-24 00:00:00

abstract：:I2-imidazoline receptors (I2-IR) are characterized by their high affinity for imidazolines and guanidines and medium affinity for imidazolidines. The differential recognition of I2-IR by amiloride led to subtype these sites as amiloride-sensitive (I2A-IR) and amiloride-insensitive (I2B-IR). I2-IR labeled with [3H]idaz...

journal_title：Annals of the New York Academy of Sciences

authors： Olmos G,Alemany R,Boronat MA,García-Sevilla JA

更新日期：1999-06-21 00:00:00

abstract：:Evolutionary theory is undergoing an intense period of discussion and reevaluation. This, contrary to the misleading claims of creationists and other pseudoscientists, is no harbinger of a crisis but rather the opposite: the field is expanding dramatically in terms of both empirical discoveries and new ideas. In this ...

journal_title：Annals of the New York Academy of Sciences

authors： Pigliucci M

更新日期：2009-06-01 00:00:00

abstract：:Jackson's Personality Research Form E (PRF) was administered to a large, heterogeneous group of adult inpatients with diagnoses of alcohol and/or drug dependence. Cluster analysis of PRF factor scores yielded five distinct patient subtypes: hostile-dependent, cooperative-nonreflective, socially uninvolved, impulsive-u...

journal_title：Annals of the New York Academy of Sciences

authors： Allen JP,Fertig JB,Mattson ME

更新日期：1994-02-28 00:00:00

abstract：:The alteration of oligosaccharide structures through genetic manipulation of glycosyltransferase activities is now a reality. It is apparent that this technique has greater consequences on oligosaccharide structure when an exogenous enzyme is introduced into cells, and in particular when this enzyme is responsible for...

journal_title：Annals of the New York Academy of Sciences

authors： Youakim A,Shur BD

更新日期：1994-11-30 00:00:00