Stereotactic core biopsy breast and blood cell by-products: a source of material for molecular genetics research--initial experience.

Abstract:

:Stereotactic core biopsy washings and blood drop samples, routinely discarded by-products, provide satisfactory fresh cellular material for flow cytometry and molecular genetics microsatellite polymerase chain reaction (PCR) analysis for detection of loss of DNA alleles (loss of heterozygosity). Cytokeratin-positive (epithelial) cells from the core biopsy washings were sorted by means of flow cytometry prior to PCR analysis. DNA allele loss was detected in benign breast epithelial cells in three (20%) of 15 patients.

journal_name

Radiology

journal_title

Radiology

authors

Stomper PC,Stewart CC,Stoler DL

doi

10.1148/radiology.218.3.r01mr11881

subject

Has Abstract

pub_date

2001-03-01 00:00:00

pages

881-5

issue

3

eissn

0033-8419

issn

1527-1315

journal_volume

218

pub_type

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