High-flow nasal cannulae in the management of apnea of prematurity: a comparison with conventional nasal continuous positive airway pressure.

Abstract:

:Apnea of prematurity (AOP) is frequently managed with nasal continuous positive airway pressure (NCPAP). Nasal cannula (NC) are used at low flows (<0.5 L/min) to deliver supplemental oxygen to neonates. A number of centers use high-flow nasal cannula (HFNC) in the management of AOP without measuring the positive distending pressure (PDP) generated. Objective. To determine the NC flow required to generate PDP equal to that provided by NCPAP at 6 cm H(2)O and to assess the effectiveness of HFNC as compared NCPAP in the management of AOP. Method. Forty premature infants, gestation 28.7 +/- 0.4 weeks (mean +/- standard error of mean), postconceptual age at study 30.3 +/- 0.6 weeks, birth weight 1256 +/- 66 g, study weight 1260 +/- 63 g who were being managed with conventional NCPAP for at least 24 hours for clinically significant apnea of prematurity, were enrolled in a trial of ventilator-generated conventional NCPAP versus infant NC at flows of up to 2.5 L/min. End expiratory esophageal pressure was measured on NCPAP and on NC, and the gas flow on NC was adjusted to generate an end expiratory esophageal pressure equal to that measured on NCPAP. Two 6-hour periods were continuously recorded and the data were stored on computer. Results. The flow required to generate a comparable PDP with NC varied with the infant's weight and was represented by the equation: flow (L/min) = 0.92 + 0.68x, x = weight in kg, R = 0.72. There was no difference in the frequency and duration of apnea, bradycardia or desaturation per recording between the 2 systems. Conclusion. NC at flows of 1 to 2.5 L/min can deliver PDP in premature neonates. HFNC is as effective as NCPAP in the management of AOP.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Sreenan C,Lemke RP,Hudson-Mason A,Osiovich H

doi

10.1542/peds.107.5.1081

subject

Has Abstract

pub_date

2001-05-01 00:00:00

pages

1081-3

issue

5

eissn

0031-4005

issn

1098-4275

journal_volume

107

pub_type

临床试验,杂志文章
  • Effectiveness of zinc supplementation plus oral rehydration salts compared with oral rehydration salts alone as a treatment for acute diarrhea in a primary care setting: a cluster randomized trial.

    abstract:OBJECTIVE:The purpose of this work was to evaluate whether education about zinc supplements and provision of zinc supplements to caregivers is effective in the treatment of acute diarrhea and whether this strategy adversely affects the use of oral rehydration salts. PATIENTS AND METHODS:Six clusters of 30,000 people e...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2007-1939

    authors: Bhandari N,Mazumder S,Taneja S,Dube B,Agarwal RC,Mahalanabis D,Fontaine O,Black RE,Bhan MK

    更新日期:2008-05-01 00:00:00

  • Comparison of perinatal outcomes among TennCare managed care organizations.

    abstract:OBJECTIVE:To compare perinatal outcomes among the managed care organizations (MCOs) providing care to beneficiaries enrolled in TennCare, Tennessee's capitated Medicaid managed care program. DESIGN:Retrospective cohort analysis. SUBJECTS:Infants born in Tennessee during 1995 to women enrolled in TennCare. PRIMARY OU...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.104.3.525

    authors: Cooper WO,Hickson GB,Mitchel EF Jr,Ray WA

    更新日期:1999-09-01 00:00:00

  • Risk stratification of children being evaluated for intussusception.

    abstract:CONTEXT:Intussusception is the most common cause of intestinal obstruction in young children, and delayed diagnosis may lead to bowel perforation. OBJECTIVE:To determine predictive clinical criteria and develop a decision tree to risk-stratify children with possible intussusception. DESIGN/METHODS:This is a prospecti...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-2432

    authors: Weihmiller SN,Buonomo C,Bachur R

    更新日期:2011-02-01 00:00:00

  • Hemoglobin S and C traits: contributing causes for decreased mean hematocrit in African-American children.

    abstract::Several nutritional surveys have shown that African-American children have lower mean hematocrit and hemoglobin values than white children. While the high prevalence of both alpha and beta thalassemias in African-American children can partly account for the lower hematologic values, the remaining differences cannot be...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Rana SR,Sekhsaria S,Castro OL

    更新日期:1993-04-01 00:00:00

  • Quality Improvement Incorporating a Feedback Loop for Accurate Medication Reconciliation.

    abstract:OBJECTIVES:Medication reconciliation errors on hospital admission can lead to significant patient harm. A pediatric intermediate care unit initiated a quality improvement project and aimed to reduce errors in admission medication reconciliation by 50% in 12 months. METHODS:From August 2017 to December 2018, a multidis...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-2464

    authors: Russ CM,Stone S,Treseler J,Vincuilla J,Partin L,Jones E,Chu E,Currier D,Kelly DP

    更新日期:2020-12-01 00:00:00

  • Lead exposure in children: prevention, detection, and management.

    abstract::Fatal lead encephalopathy has disappeared and blood lead concentrations have decreased in US children, but approximately 25% still live in housing with deteriorated lead-based paint and are at risk of lead exposure with resulting cognitive impairment and other sequelae. Evidence continues to accrue that commonly encou...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章,实务指引

    doi:10.1542/peds.2005-1947

    authors: American Academy of Pediatrics Committee on Environmental Health.

    更新日期:2005-10-01 00:00:00

  • FDA's pediatric device consortia: national program fosters pediatric medical device development.

    abstract:OBJECTIVES:This article reports on the progress made in addressing pediatric medical device needs through the establishment of the Pediatric Device Consortia Grant Program. Pediatric practitioners should be aware of both the imperative for well-studied devices for children and the existence of recently created resource...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2012-1534

    authors: Ulrich LC,Joseph FD,Lewis DY,Koenig RL

    更新日期:2013-05-01 00:00:00

  • Ten-year prospective study of public health problems associated with early drinking.

    abstract:OBJECTIVE:To compare early nondrinkers, experimenters, and drinkers on the prevalence of problem behaviors at grades 7 and 12 and at age 23 (N = 6338, 4265, and 3369, respectively). METHODS:Results are based on longitudinal self-report data from individuals who were originally recruited from 30 California and Oregon s...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.111.5.949

    authors: Ellickson PL,Tucker JS,Klein DJ

    更新日期:2003-05-01 00:00:00

  • Recognizing and responding to medical neglect.

    abstract::A caregiver may fail to recognize or respond to a child's medical needs for a variety of reasons. An effective response by a health care professional to medical neglect requires a comprehensive assessment of the child's needs, the parents' resources, the parents' efforts to provide for the needs of the child, and opti...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2007-2903

    authors: Jenny C,Committee on Child Abuse and Neglect, American Academy of Pediatrics.

    更新日期:2007-12-01 00:00:00

  • Emergency Department and Hospital Use Among Adolescents With Justice System Involvement.

    abstract:OBJECTIVES:Adolescents with justice system involvement have high rates of physical and behavioral health disorders and are potentially high users of costly health care services. We examined emergency department (ED) and hospital use among a national sample of adolescents with various levels of justice involvement. MET...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-1144

    authors: Winkelman TNA,Genao I,Wildeman C,Wang EA

    更新日期:2017-11-01 00:00:00

  • Adolescent E-Cigarette, Hookah, and Conventional Cigarette Use and Subsequent Marijuana Use.

    abstract::: media-1vid110.1542/5799875103001PEDS-VA_2017-3616Video Abstract OBJECTIVES: Noncigarette tobacco products may confer a risk of marijuana use similar to combustible cigarettes. We examined whether adolescent electronic cigarette (e-cigarette), hookah, or combustible cigarette use is associated with initiating and cur...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-3616

    authors: Audrain-McGovern J,Stone MD,Barrington-Trimis J,Unger JB,Leventhal AM

    更新日期:2018-09-01 00:00:00

  • Thrombotic storm in a teenager with previously undiagnosed ulcerative colitis.

    abstract::Venous thrombosis can complicate inflammatory bowel diseases, both in adult and pediatric patients, and a few adult cases of thrombotic storm, ie, thrombosis at multiple sites occurring over a period of a few days to a few weeks, have been described. However, venous thrombosis as the first manifestation of an inflamma...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2012-2365

    authors: Maggi U,Rossi G,Avesani EC,Artoni A,Caprioli F,Napolitano L,Martinelli I

    更新日期:2013-04-01 00:00:00

  • Prolonged use of large intravenous steroid pulses in the rheumatic diseases of children.

    abstract::Nineteen children with rheumatic diseases refractory to standard treatment were given repeated large "pulses" of corticosteroid therapy. The pulses consisted of four repeated doses of 500 mg of hydrocortisone given intravenously over 20 to 30 minutes at six-hour intervals or of single intravenous injections of 30 mg/k...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Miller JJ 3rd

    更新日期:1980-05-01 00:00:00

  • A Multicenter Collaborative to Improve Care of Community Acquired Pneumonia in Hospitalized Children.

    abstract:BACKGROUND AND OBJECTIVES:The Value in Inpatient Pediatrics Network sponsored the Improving Care in Community Acquired Pneumonia collaborative with the goal of increasing evidence-based management of children hospitalized with community acquired pneumonia (CAP). Project aims included: increasing use of narrow-spectrum ...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2016-1411

    authors: Parikh K,Biondi E,Nazif J,Wasif F,Williams DJ,Nichols E,Ralston S,Value in Inpatient Pediatrics Network Quality Collaborative For Improving Care In Community Acquired Pneumonia.

    更新日期:2017-03-01 00:00:00

  • The safe environment for every kid model: impact on pediatric primary care professionals.

    abstract:OBJECTIVE:To examine whether the Safe Environment for Every Kid (SEEK) model of enhanced primary care would improve the attitudes, knowledge, comfort, competence, and behavior of child health care professionals (HPs) regarding addressing major risk factors for child maltreatment (CM). METHODS:In a cluster randomized c...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2010-1845

    authors: Dubowitz H,Lane WG,Semiatin JN,Magder LS,Venepally M,Jans M

    更新日期:2011-04-01 00:00:00

  • Temperament and behavior of preterm infants: a six-year follow-up.

    abstract::To test the commonly held premise that prematurity is a risk factor for problems of behavior and social interaction, as well as cognitive and physical development, temperament and behavior of children born preterm and full-term control subjects were compared at five separate time periods from infancy through early sch...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Oberklaid F,Sewell J,Sanson A,Prior M

    更新日期:1991-06-01 00:00:00

  • Increased blood pressure following pupillary dilation with 2.5% phenylephrine hydrochloride in preterm infants.

    abstract::Heart rate and blood pressure changes following 0.5% tropicamide and 2.5% phenylephrine hydrochloride were evaluated in seven ill preterm infants (birth weight, 910 to 2,060 gm; gestational age, 26 to 36 weeks) during the first day of life. Each infant was monitored continuously for 30 minutes before and for 75 minute...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Lees BJ,Cabal LA

    更新日期:1981-08-01 00:00:00

  • Preschool child care participation and obesity at the start of kindergarten.

    abstract:OBJECTIVE:We examined the association between type of child care, participation in different types of child care in the year before kindergarten and the likelihood of obesity at the start of kindergarten. METHODS:Using a nationally representative sample of 15 691 first-time kindergartners from the Early Childhood Long...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-2233

    authors: Maher EJ,Li G,Carter L,Johnson DB

    更新日期:2008-08-01 00:00:00

  • Common and costly hospitalizations for pediatric mental health disorders.

    abstract:BACKGROUND AND OBJECTIVES:Inpatient pediatric mental health is a priority topic for national quality measurement and improvement, but nationally representative data on the patients admitted or their diagnoses are lacking. Our objectives were: to describe pediatric mental health hospitalizations at general medical facil...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2013-3165

    authors: Bardach NS,Coker TR,Zima BT,Murphy JM,Knapp P,Richardson LP,Edwall G,Mangione-Smith R

    更新日期:2014-04-01 00:00:00

  • Should Neonatologists Give Opinions Withdrawing Life-sustaining Treatment?

    abstract::An infant has a massive intracranial hemorrhage. She is neurologically devastated and ventilator-dependent. The prognosis for pulmonary or neurologic recovery is bleak. The physicians and parents face a choice: withdraw the ventilator and allow her to die or perform a tracheotomy? The parents cling to hope for recover...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2016-2585

    authors: Blumenthal-Barby JS,Loftis L,Cummings CL,Meadow W,Lemmon M,Ubel PA,McCullough L,Rao E,Lantos JD

    更新日期:2016-12-01 00:00:00

  • Cultural bias in the AAP's 2012 Technical Report and Policy Statement on male circumcision.

    abstract::The American Academy of Pediatrics recently released its new Technical Report and Policy Statement on male circumcision, concluding that current evidence indicates that the health benefits of newborn male circumcision outweigh the risks. The technical report is based on the scrutiny of a large number of complex scient...

    journal_title:Pediatrics

    pub_type: 评论,杂志文章

    doi:10.1542/peds.2012-2896

    authors: Frisch M,Aigrain Y,Barauskas V,Bjarnason R,Boddy SA,Czauderna P,de Gier RP,de Jong TP,Fasching G,Fetter W,Gahr M,Graugaard C,Greisen G,Gunnarsdottir A,Hartmann W,Havranek P,Hitchcock R,Huddart S,Janson S,Jaszczak P

    更新日期:2013-04-01 00:00:00

  • Pediatric cardiac surgery: the effect of hospital and surgeon volume on in-hospital mortality.

    abstract:OBJECTIVE:To examine the relationship between annual provider (hospital and surgeon) volume of pediatric cardiac surgery and in-hospital mortality. DESIGN:Population-based retrospective cohort study using a clinical database. SETTING:The 16 acute care hospitals in New York with certificate of need approval to perform...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.101.6.963

    authors: Hannan EL,Racz M,Kavey RE,Quaegebeur JM,Williams R

    更新日期:1998-06-01 00:00:00

  • Inequality of access to surgical specialty health care: why children with government-funded insurance have less access than those with private insurance in Southern California.

    abstract:OBJECTIVE:More than 25 million children in the United States are dependent on federal and state medical insurance programs for their health care needs. In California, 3.25 million children depend on Medi-Cal for their health insurance. In Southern California alone, the figure is as high as 1.81 million. However, 9.30 m...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-0210

    authors: Wang EC,Choe MC,Meara JG,Koempel JA

    更新日期:2004-11-01 00:00:00

  • Antibiotic Prophylaxis for Children With Sickle Cell Anemia.

    abstract:BACKGROUND:Children with sickle cell anemia (SCA) are at increased risk for invasive pneumococcal disease; antibiotic prophylaxis significantly reduces this risk. We calculated the proportion of children with SCA who received ≥300 days of antibiotic prophylaxis and identified predictors of such receipt. METHODS:Childr...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-2182

    authors: Reeves SL,Tribble AC,Madden B,Freed GL,Dombkowski KJ

    更新日期:2018-03-01 00:00:00

  • Parental smoking and vascular damage in their 5-year-old children.

    abstract:BACKGROUND:The relation between smoke exposure in early life, the prenatal period in particular, and the vascular development of young children is largely unknown. METHODS:Data from the birth cohort participating in the WHISTLER-Cardio study were used to relate the smoking of parents during pregnancy to subsequent vas...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2011-0249

    authors: Geerts CC,Bots ML,van der Ent CK,Grobbee DE,Uiterwaal CS

    更新日期:2012-01-01 00:00:00

  • Screening tests for urinary tract infection in children: A meta-analysis.

    abstract:OBJECTIVE:To review systematically and to summarize the existing literature regarding performance of rapid diagnostic tests for urinary tract infection (UTI) in children. DESIGN:Systematic review and meta-analysis. METHODS:Published articles reporting the performance of urine dipstick tests (leukocyte esterase [LE] a...

    journal_title:Pediatrics

    pub_type: 杂志文章,meta分析

    doi:10.1542/peds.104.5.e54

    authors: Gorelick MH,Shaw KN

    更新日期:1999-11-01 00:00:00

  • Increased rates of morbidity, mortality, and charges for hospitalized children with public or no health insurance as compared with children with private insurance in Colorado and the United States.

    abstract:BACKGROUND:There has been a gradual decrease in the proportion of children covered by private health insurance in Colorado and the United States with a commensurate increase in those with public insurance or having no insurance which may impact access to care and outcomes. OBJECTIVE:The purpose of this work was to det...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-0162

    authors: Todd J,Armon C,Griggs A,Poole S,Berman S

    更新日期:2006-08-01 00:00:00

  • Spontaneous Closure of Patent Ductus Arteriosus in Infants ≤1500 g.

    abstract:OBJECTIVES:Patent ductus arteriosus (PDA) remains a challenging issue in very low birth weight (VLBW) infants, and its management varies widely. Our aim in this study was to document the natural course of ductus arteriosus in a cohort of VLBW infants who underwent conservative PDA management with no medical or surgical...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-4258

    authors: Semberova J,Sirc J,Miletin J,Kucera J,Berka I,Sebkova S,O'Sullivan S,Franklin O,Stranak Z

    更新日期:2017-08-01 00:00:00

  • Special requirements of electronic health record systems in pediatrics.

    abstract::Some functions of an electronic health record system are much more important in providing pediatric care than in adult care. Pediatricians commonly complain about the absence of these "pediatric functions" when they are not available in electronic health record systems. To stimulate electronic health record system ven...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-3527

    authors: Spooner SA,Council on Clinical Information Technology, American Academy of Pediatrics.

    更新日期:2007-03-01 00:00:00

  • Childhood urolithiasis: experiences and advances.

    abstract::Between June 1979 and June 1989, 54 children with urolithiasis were evaluated and treated at the Johns Hopkins Children's Center. The most common symptoms were flank or abdominal pain (58%) and gross hematuria (28%). In 46 children (86%), stones were secondary to a preexisting condition and in only 8 (14%) no apparent...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Gearhart JP,Herzberg GZ,Jeffs RD

    更新日期:1991-04-01 00:00:00