Spinal cord lesions.

Abstract:

:Selected topics related to rehabilitation of individuals with spinal cord lesions are reviewed and commented upon. A 10-week arm-cranking programme improved aerobic capacity and endurance in tetraplegics. Furthermore, endurance training and forced vital capacity were found to be positively correlated. Rowing had additional positive effects for scapular retractor recruitment, which may well improve the shoulder stability. Increased abdominal circumference is an important correlate to dyslipidaemia. beta 2-adrenergic agonists can improve muscle strength and size even without simultaneous exercise. Hydrophilic low-friction catheters, for clean intermittent catheterization have performed as well as, or better than, conventional catheters in a long-term follow-up study. Urethral stenting of the bladder neck and the external sphincter seems, in selected patients, to be an attractive alternative to indwelling urethral catheter drainage or sphincterotomy. The majority (> 80%) of the first 500 sacral anterior root stimulators are still in use for micturition and for defecation. The management of impotence in men with spinal cord lesions using intercavernous injections has been confirmed, and oral terbutaline (5 mg) may be used to achieve penile detumescence in cases of prolonged erection. The use of penile implants in men with spinal cord lesions is a problem. Penile vibration with a peak-to-peak amplitude of 2.5 mm is sufficient to obtain ejaculation in most of these men. Age is more important for sexual adjustment than whether the relationship is established before or after the injury. Regular and frequent follow-up of patients with spinal cord injury is the best way to ensure that post-traumatic syringomyelia is diagnosed and managed (surgically drained) early in order to avoid further disability. Two-thirds of individuals with spinal cord injury rate their quality of life as good. Socialization is important in obtaining a good quality of life. Psychological morbidity in the first 2 years after the injury is found in approximately one-third of the population with spinal cord injury; antidepressant drugs should perhaps be used more widely.

journal_name

Curr Opin Neurol

authors

Biering-Sørensen F,Hartkopp A

doi

10.1097/00019052-199512000-00010

subject

Has Abstract

pub_date

1995-12-01 00:00:00

pages

451-5

issue

6

eissn

1350-7540

issn

1473-6551

journal_volume

8

pub_type

杂志文章,评审
  • Magnetic resonance spectroscopy in multiple sclerosis: window into the diseased brain.

    abstract::Magnetic resonance spectroscopy provides noninvasive insight into the regional and global biochemical alterations that are concomitants of the dynamic processes that underlie the evolution of fundamental pathologic changes in multiple sclerosis. These include now well-recognized alterations of neuronal biochemical mar...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/00019052-200206000-00004

    authors: Wolinsky JS,Narayana PA

    更新日期:2002-06-01 00:00:00

  • Epidemiology and natural history of multiple sclerosis: new insights.

    abstract:PURPOSE OF REVIEW:The cause of multiple sclerosis remains elusive. We review recent epidemiological studies of genetic and environmental factors that influence susceptibility to the disease and its clinical course. RECENT FINDINGS:Genetic advances strengthen the association of multiple sclerosis with the human leukocy...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/01.wco.0000227033.47458.82

    authors: Kantarci O,Wingerchuk D

    更新日期:2006-06-01 00:00:00

  • Calcium channel mutations and migraine.

    abstract::An increasing number of mutations in the CACNA1A gene have been identified, which are associated with a broad clinical spectrum, including familial hemiplegic migraine. Transfection studies and mouse model analyses are currently being undertaken to study the correlation between CACNA1A mutations and disease. ...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/00019052-200206000-00014

    authors: Kors EE,van den Maagdenberg AM,Plomp JJ,Frants RR,Ferrari MD

    更新日期:2002-06-01 00:00:00

  • Genetic treatments in muscular dystrophies.

    abstract:PURPOSE OF REVIEW:The search for a cure for Duchenne muscular dystrophy and other muscular dystrophies is progressing rapidly despite significant challenges posed by some genes and the complexity of targeting all skeletal muscles. This review focuses on three areas in which experimental clinical studies are in progress...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0b013e3282efc157

    authors: Muntoni F,Wells D

    更新日期:2007-10-01 00:00:00

  • Functional (psychogenic) movement disorders.

    abstract:PURPOSE OF REVIEW:This review provides an overview of recent developments in diagnosis, pathophysiology, neuroimaging and management of functional (psychogenic) movement disorders (FMD). RECENT FINDINGS:There has been increasing interest to study the underlying pathophysiology of FMD, which has resulted in a broadened...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0b013e3283551bc1

    authors: Czarnecki K,Hallett M

    更新日期:2012-08-01 00:00:00

  • Traumatic brain injury: recent advances in plasticity and regeneration.

    abstract:PURPOSE OF REVIEW:There is an urgent need for effective therapies to restore neurologic function and decrease disability following traumatic brain injury (TBI). Here, emerging findings on the mechanisms of post-TBI neural repair and regeneration, as well as therapeutic implications, are selectively reviewed. RECENT FI...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0000000000000265

    authors: Werner JK,Stevens RD

    更新日期:2015-12-01 00:00:00

  • Primary and secondary ataxias.

    abstract:PURPOSE OF REVIEW:This article discusses recent advances in the understanding of clinical and genetic aspects of primary ataxias, including congenital, autosomal recessive, autosomal dominant, episodic, X-linked, and mitochondrial ataxias, as well as idiopathic degenerative and secondary ataxias. RECENT FINDINGS:Many ...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0000000000000227

    authors: Teive HA,Ashizawa T

    更新日期:2015-08-01 00:00:00

  • The pupil.

    abstract:PURPOSE OF REVIEW:To give an overview on topics of pupillary function selected according to their relevance in clinical neurology. Mainly publications of the last 3 years have been considered. RECENT FINDINGS:The discovery of photosensitive retinal ganglion cells not serving vision, but serving circadian rhythm and th...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章

    doi:10.1097/WCO.0b013e3282f39173

    authors: Wilhelm H

    更新日期:2008-02-01 00:00:00

  • Neurorehabilitation in multiple sclerosis: foundations, facts and fiction.

    abstract:PURPOSE OF REVIEW:This review of recent work in the area of neurorehabilitation of multiple sclerosis patients surveys progress and underscores the need for further work to evaluate the effectiveness of treatments. RECENT FINDINGS:Several recent review documents have summarized the current position regarding neuroreha...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/01.wco.0000169743.37159.a0

    authors: Thompson AJ

    更新日期:2005-06-01 00:00:00

  • The latest on functional imaging studies of aphasic stroke.

    abstract:PURPOSE OF REVIEW:Functional neuro-imaging studies of aphasic stroke offer the potential for a better understanding of the neuronal mechanisms that sustain language recovery. Conclusions, however, have been hampered by a set of unexpected challenges related to experimental design and interpretation. In this review of s...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/01.wco.0000168081.76859.c1

    authors: Price CJ,Crinion J

    更新日期:2005-08-01 00:00:00

  • Autoantibodies in immune-mediated neuropathies.

    abstract:PURPOSE OF REVIEW:Over the past 25 years, many autoantibodies directed against peripheral nerve glycan and protein antigens have been described. Principally through this area of research, significant advances have been achieved in the understanding of the pathophysiology of inflammatory neuropathies. More evidence cons...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0b013e328357a77f

    authors: Chavada G,Willison HJ

    更新日期:2012-10-01 00:00:00

  • New nuclear magnetic resonance data in epilepsy.

    abstract::Nuclear magnetic resonance methods as a whole have contributed as much to the study and treatment of epilepsy as to any branch of medicine. The pace of the progress in this field increases as recently developed nuclear magnetic resonance techniques mature into practical tools for epilepsy research and management. Rece...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/00019052-199704000-00005

    authors: Prichard JW

    更新日期:1997-04-01 00:00:00

  • Functional brain imaging applications to differential diagnosis in the dementias.

    abstract:PURPOSE OF REVIEW:The diagnosis of dementia rests on an improved knowledge and a better detection of early impairments, to which functional imaging can certainly contribute. RECENT FINDINGS:Progress has been observed at different levels. First, the understanding of different dementias has benefited from explorations o...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/00019052-200208000-00006

    authors: Salmon E

    更新日期:2002-08-01 00:00:00

  • New management algorithms in multiple sclerosis.

    abstract:PURPOSE OF REVIEW:Our current treatment algorithms include only IFN-β and glatiramer as available first-line disease-modifying drugs and natalizumab and fingolimod as second-line therapies. Today, 10 drugs have been approved in Europe and nine in the United States making the choice of therapy more complex. The purpose ...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0000000000000096

    authors: Sorensen PS

    更新日期:2014-06-01 00:00:00

  • Recent advances in status epilepticus.

    abstract:PURPOSE OF REVIEW:This review discusses advances in the understanding of the mechanisms of status epilepticus and its current treatment approaches. Many of these have been topics at the 5th London-Innsbruck Colloquium on status epilepticus 2015. RECENT FINDINGS:A new definition and classification of status epilepticus...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0000000000000307

    authors: Trinka E,Brigo F,Shorvon S

    更新日期:2016-04-01 00:00:00

  • Advances in ultra-high field MRI for the clinical management of patients with brain tumors.

    abstract:PURPOSE OF REVIEW:The last 5 years have seen the number of ultra-high field (UHF; 7 T and beyond) MRI scanners nearly double. Benefits include improved specificity, better sensitivity for signal-starved compounds, and the ability to detect, quantify, and monitor tumor activity and treatment effects. This is especially ...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0b013e32834cd495

    authors: Lupo JM,Li Y,Hess CP,Nelson SJ

    更新日期:2011-12-01 00:00:00

  • Prism adaptation in the rehabilitation of patients with visuo-spatial cognitive disorders.

    abstract:PURPOSE OF REVIEW:The traditional focus of neurorehabilitaion has been on the patients' attention on their deficit, such that they should become aware of their problems and gain intentional control of compensatory strategies (descending approach). We review prism adaptation as one of the approaches that emphasize ascen...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0b013e328010924b

    authors: Pisella L,Rode G,Farnè A,Tilikete C,Rossetti Y

    更新日期:2006-12-01 00:00:00

  • Exotic and emerging viral encephalitides.

    abstract:PURPOSE OF REVIEW:The exotic and emerging viral encephalitides are caused by animal or human viruses and characterised by sudden unexpected outbreaks of neurological disease, usually in tropical and sub-tropical regions, but sometimes spreading to temperate areas. Although a wide range of viruses come within this label...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/01.wco.0000073944.19076.56

    authors: Solomon T

    更新日期:2003-06-01 00:00:00

  • Thrombolysis for acute stroke.

    abstract:PURPOSE OF REVIEW:Stroke thrombolysis is in the process of moving from academic centers into community-based standard therapy in experienced centers. Recently published data on patient selection, imaging and other technical or organizational advances are reviewed in order to improve the safety and efficacy of stroke th...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/01.wco.0000053584.70044.65

    authors: Lindsberg PJ,Kaste M

    更新日期:2003-02-01 00:00:00

  • Advances in memory research: single-neuron recordings from the human medial temporal lobe aid our understanding of declarative memory.

    abstract:PURPOSE OF REVIEW:To gain a complete understanding of how the brain functions, both in illness and good health, data from multiple levels of analysis must be integrated. Technical advances have made direct recordings of neuronal activity deep inside the human brain tractable, providing a rare glimpse into cellular proc...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0b013e3283168e03

    authors: Viskontas IV

    更新日期:2008-12-01 00:00:00

  • What have we learned from recent twin studies about the etiology of neurodevelopmental disorders?

    abstract:PURPOSE OF REVIEW:The relative influence of genes and environment on the liability to neurodevelopmental disorders (NDDs) can be investigated using a twin design. This review highlights the results of the most recent twin studies of NDDs. RECENT FINDINGS:Recent twin studies have confirmed that NDDs show moderate-to-hi...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0b013e32835f19c3

    authors: Posthuma D,Polderman TJ

    更新日期:2013-04-01 00:00:00

  • Health and well being of adults with cerebral palsy.

    abstract:PURPOSE OF REVIEW:This article reviews what is known about the health and well being of adults with cerebral palsy. It also addresses the factors known to affect the areas identified in the World Health Organization International Classification of Functioning model as being critical for optimal health and well being. ...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0b013e3282f6a499

    authors: Liptak GS

    更新日期:2008-04-01 00:00:00

  • Update on the treatment of chronic inflammatory demyelinating polyradiculoneuropathy.

    abstract:PURPOSE OF REVIEW:Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a chronic and often disabling neuropathy, which often responds to immune therapies including corticosteroids, plasma exchange, and high-dose intravenous immunoglobulin (IVIg). The reasons for choosing one of these therapies and the fa...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0000000000000232

    authors: Nobile-Orazio E,Gallia F

    更新日期:2015-10-01 00:00:00

  • Migraine: a brain state.

    abstract:PURPOSE OF REVIEW:Migraine has traditionally been categorized as a pain disorder, focusing on headache as its central feature. This narrow view does not account for the complex array of premonitory and postrdromal symptoms that occur in the hours before and after headache. This review outlines evidence that supports a ...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0b013e32836085f4

    authors: Charles A

    更新日期:2013-06-01 00:00:00

  • Metabolic imaging in the diagnosis of brain tumors.

    abstract::Positron emission tomography, single photon emission computed tomography and magnetic resonance spectroscopy provide distinct, uncorrelated and sensitive indicators of brain tumors which can be used to improve differential diagnosis, biopsy guidance or therapy monitoring. New findings, including conflicting ethyl-cyst...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/00019052-199612000-00006

    authors: Slosman DO,Lazeyras F

    更新日期:1996-12-01 00:00:00

  • The changing landscape of motor neuron disease imaging: the transition from descriptive studies to precision clinical tools.

    abstract:PURPOSE OF REVIEW:Neuroimaging in motor neuron disease (MND) has traditionally been seen as an academic tool with limited direct relevance to individualized patient care. This has changed radically in recent years as computational imaging has emerged as a viable clinical tool with true biomarker potential. This transit...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0000000000000569

    authors: Bede P,Querin G,Pradat PF

    更新日期:2018-08-01 00:00:00

  • Acquired myasthenia gravis in childhood.

    abstract:PURPOSE OF REVIEW:This review discusses recent studies on myasthenia gravis with onset in childhood (juvenile myasthenia gravis) and neonatal myasthenia gravis. RECENT FINDINGS:The occurrence of myasthenia gravis in childhood is strongly influenced by genetic and environmental factors. Juvenile myasthenia gravis is as...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0b013e32833c32af

    authors: Evoli A

    更新日期:2010-10-01 00:00:00

  • Myelin oligodendrocyte glycoprotein antibodies: How clinically useful are they?

    abstract:PURPOSE OF REVIEW:Serum IgG autoantibodies against the myelin oligodendrocyte glycoprotein (MOG) are present in atypical demyelinating disorders such as neuromyelitis optica spectrum disorders (NMOSD) or acute disseminated encephalomyelitis. Whereas the role of aquaporin-4 antibodies as diagnostic markers for NMOSD is ...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0000000000000446

    authors: Reindl M,Jarius S,Rostasy K,Berger T

    更新日期:2017-06-01 00:00:00

  • Neurochemical biomarkers in amyotrophic lateral sclerosis.

    abstract:PURPOSE OF REVIEW:The diagnosis of amyotrophic lateral sclerosis (ALS) still relies mainly on clinical criteria. In present review we will provide an overview of neurochemical ALS biomarkers, which are in the most advanced position on the way towards inclusion into the clinical work-up. RECENT FINDINGS:The field of AL...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章,评审

    doi:10.1097/WCO.0000000000000744

    authors: Verde F,Silani V,Otto M

    更新日期:2019-10-01 00:00:00

  • Progress in the therapy of myasthenia gravis: getting closer to effective targeted immunotherapies.

    abstract:PURPOSE OF REVIEW:To provide an update on immunomodulating and immunosuppressive therapies in myasthenia gravis and highlight newly approved, or pending approval, therapies with new biologics. RECENT FINDINGS:Preoperative IVIg is not needed to prevent myasthenic crisis in stable myasthenia gravis patients scheduled fo...

    journal_title:Current opinion in neurology

    pub_type: 杂志文章

    doi:10.1097/WCO.0000000000000858

    authors: Dalakas MC

    更新日期:2020-10-01 00:00:00