Prophylactic phenytoin in severe head injuries.

Abstract:

:We are reporting a retrospective study of 62 patients whose head injury was sufficiently severe to cause a high probability of posttraumatic epilepsy. Of 50 patients treated with phenytoin, 10% developed epilepsy of late onset. Twelve patients not treated with phenytoin but who had head injuries of equal magnitude had a 50% incidence of epilepsy. These data from a highly selected group of patients with severe head injuries confirm the bias that treatment with phenytoin decreases the incidence of posttraumatic epilepsy.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Wohns RN,Wyler AR

doi

10.3171/jns.1979.51.4.0507

subject

Has Abstract

pub_date

1979-10-01 00:00:00

pages

507-9

issue

4

eissn

0022-3085

issn

1933-0693

journal_volume

51

pub_type

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