Abstract:
:Nuclear receptors for retinoids were discovered in 1987 and appeared to belong to the superfamily of steroid/thyroid hormone receptors characterized by a common structure in which the different functions (trans-activation, DNA binding and ligand binding) are present in discrete modular domains in the protein. Retinoid receptors, however, are characterized by several unique features: a multiplicity of receptors and ligands, heterodimer formation and multiple direct repeats as response elements. All these mechanisms are exploited by retinoid receptors to fulfil their multiple tasks in controlling growth, development, differentiation and carcinogenesis.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
van der Saag PTsubject
Has Abstractpub_date
1996-07-01 00:00:00pages
S24-8eissn
0954-3007issn
1476-5640journal_volume
50 Suppl 3pub_type
杂志文章,评审abstract:BACKGROUND/OBJECTIVES:Young Indian adults are at greater risk of overweight/obesity due to their high energy intake and sedentary lifestyle. Their energy requirement (ER) is based on their total energy expenditure (TEE) estimated from factorial method, which possibly overestimates their basal metabolic rate (BMR) and p...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-020-00790-5
更新日期:2020-10-24 00:00:00
abstract:OBJECTIVE:To assess the effects of dietary supplementation using two isomeric blends of conjugated linoleic acid (CLA) on immune function in healthy human volunteers. DESIGN:Double-blind, randomised, placebo-controlled intervention trial. SUBJECTS AND INTERVENTION:A total of 55 healthy volunteers (n=20 males, n=35 fe...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602132
更新日期:2005-06-01 00:00:00
abstract::The effect of adjusting height-weight indices for frame size on the prediction of body fatness was investigated in a community sample of 2512 men aged 45-59 years. Body fatness was assessed from skinfold thickness measurements at four sites: triceps, biceps, subscapular and supra-iliac. Body diameters (biacromial, bi-...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1990-02-01 00:00:00
abstract::The effect on total serum cholesterol and its lipoprotein fractions of supplementation of the diet with amla (Emblica officinalis, Gaertn., the Indian gooseberry) was studied in normal and hypercholesterolaemic men aged 35-55 years. The supplement was given for a period of 28 d in the raw form. Both normal and hyperch...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1988-11-01 00:00:00
abstract::The application of molecular biology and genetics in the field of cholesterol and lipoprotein metabolism has resulted in a tremendous expansion of knowledge during the past decade. In this short review, the normal metabolism of lipoproteins is first discussed briefly, and several clinically important examples of genet...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:1992-03-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The risk factors for metabolic syndrome may differ between Western and Asian countries due to their distinct dietary cultures. However, few studies have directly compared macronutrient intake and its association with the risk of metabolic syndrome in the US and Korean adults using national survey ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-017-0031-8
更新日期:2018-06-01 00:00:00
abstract::Dialysis patients are at increased risk for muscle wasting, and time efficient screening tests are required for to allow for early detection. Creatinine kinetics have been advocated to estimate lean body mass (LBM) in peritoneal dialysis (PD) patients, and can be readily calculated in clinical practice from peritoneal...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-017-0072-z
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Anemia, leukopenia and, although less frequently, thrombocytopenia are possible hematological complications of anorexia nervosa considered strictly secondary to chronic malnutrition. This is a retrospective study on the prevalence of these disorders in a large cohort of 318 female patients with AN...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.115
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To assess the long-term effect of dietary advice on diet and mortality after a randomised trial of men with a recent history of myocardial infarction. DESIGN:Questionnaire survey and mortality follow-up after a trial of dietary advice. SETTING:Twenty-one hospitals in south Wales and south-west England. SUB...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601342
更新日期:2002-06-01 00:00:00
abstract::Consumers and patients are unsure of whom to trust for nutritional advice. Although medical doctors are seen as experts in nutrition and their advice is regularly followed, data are lacking on the amount of nutrition education in European medical school curricula. In line with US research, we distributed a survey on r...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2014.75
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The Dutch guidelines for a healthy diet aim to reduce major chronic diseases. However, supporting evidence on their overall association with all-cause and cause-specific mortality is limited. Recently, the Dutch Healthy Diet-index (DHD-index) has been developed to assess adherence to these guideli...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2015.163
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Globally, fruit and vegetable intakes are well below recommendations despite ample evidence to link insufficient intake with increased risk of overweight and obesity. Intakes of fruits and vegetables in the general population differ between males and females, and although there is growing evidence...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2015.123
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:To provide a reference range for plasma total homocysteine (tHcy), an independent risk factor for vascular disease, and to explore relationships with nutritional indices for people aged 65 y and over, in the UK National Diet and Nutrition Survey (NDNS). DESIGN:The survey procedures described in the National...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600468
更新日期:1997-10-01 00:00:00
abstract::More than 20 years of serological approach to diagnosis of celiac disease (CD) has deeply changed the classical clinical presentation of the disease, and some reports indicate that CD and obesity can coexist in both childhood and adolescence. We reviewed clinical records of 149 children with CD followed in our institu...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.161
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:We investigated whether C-reactive protein (CRP) as indicator of acute inflammation is associated with maximal isometric handgrip strength in non-critically ill patients. SUBJECTS/METHODS:Handgrip strength was measured with Jamar dynamometer in 620 hospitalized patients (56.4±15.9 years old, 52.3...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2013.261
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To collect (i) baseline data and (ii) execute a large multicentre study examining the effect of trans alpha-linolenic acid on its incorporation into plasma lipids and on risk factors for coronary heart disease. DESIGN:Male volunteers were recruited and the habitual diet assessed by a 4-d weighed record. Fatt...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1600903
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Optimal obesity indices in predicting cardio-metabolic risk are less studied in Asian. We evaluated optimal waist-to-height ratio (WHtR) for predicting hypertension, dyslipidemia and diabetes in Han and Uygur populations in Xinjiang, a northwest part of China. SUBJECTS/METHODS:This study involved...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2015.25
更新日期:2015-08-01 00:00:00
abstract::Nonketotic hyperglycinemia (NKH) is a devastating inborn error of glycine metabolism caused by deficient activity of the glycine cleavage enzyme. Classically, patients present with lethargy, hypotonia, myoclonic jerks, transient respiratory depression in the first week of life and often progress to death. Surviving in...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0286-8
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:To compare the relations of adiposity and body fat distribution to body mass index (BMI) in Australians of Aboriginal and European ancestry. DESIGN:Cross-sectional volunteer samples. SETTING:Australian Aboriginal communities in remote central and northern Australia, urban European Australians resident in Me...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601630
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:To investigate whether the protection observed for some micronutrients, such as beta-carotene, in several observational studies may simply reflect vegetable and fruit intake. DESIGN:A case-control study conducted in Italy. SUBJECTS:The subjects were 1225 colon cancer patients, 728 rectal cancer patients and...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601317
更新日期:2002-02-01 00:00:00
abstract::Food composition tables were studied from nine European countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC): Denmark, France, Germany, Greece, Great Britain, Italy, The Netherlands, Spain and Sweden. They were compared from the point view of availability, definition, anal...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600677
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVES:To investigate the effect of three different food ingredients tyrosine, green tea extract (GTE) and caffeine on resting metabolic rate and haemodynamics, and on ad libitum energy intake (EI) and appetite. METHODS:Twelve healthy, normal weight men (age: 23.7 +/- 2.6 years, mean +/- s.d.) participated in a fo...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602901
更新日期:2009-01-01 00:00:00
abstract::The effect of mazindol given orally on gastric emptying of a radiolabelled solid meal was examined in 10 obese females. The patients underwent the measurement of gastric emptying twice: 2 mg mazindol was compared with placebo according to a double-blind study protocol. Mazindol significantly delayed gastric emptying (...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章
doi:
更新日期:1988-07-01 00:00:00
abstract:OBJECTIVE:To determine the effect on blood pressure of dietary advice to consume a combination of plant-based cholesterol-lowering foods (dietary portfolio). METHODS:For 1 year, 66 hyperlipidemic subjects were prescribed diets high in plant sterols (1.0 g/1000 kcal), soy protein (22.5 g/1000 kcal), viscous fibers (10 ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602768
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVES:To evaluate the use of a self-administered quantitative food frequency questionnaire (QFFQ) in a national dietary survey concerning (a) response rates with different distribution methods and reward; (b) degree of underreporting of energy intake; (c) reproducibility of the QFFQ; and (d) seasonal variation on ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600410
更新日期:1997-06-01 00:00:00
abstract:OBJECTIVES:To evaluate body fatness in subjects complying with common public health guidelines for lipid and alcohol intake as well as physical activity participation. SUBJECTS:A sample of 358 male subjects who participated in phase 1 of the Quebec Family Study. DESIGN:The association between adiposity, lipid and alc...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Malnutrition is a common and underrecognized clinical problem among aged institutionalized patients. The aim of this study was to investigate how well nurses recognize malnutrition in elderly patients in long-term care hospitals in Helsinki. SUBJECTS AND METHODS:In this descriptive, cross-sect...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602916
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:To measure the intake of selenium (Se) and the contribution of different food groups to Se intake in adults aged 18-64 y in Ireland. The adequacy of Se intake in the population is also assessed. DESIGN:Food consumption was estimated using a 7 day food diary for a representative sample (n=1379; men=662, women...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601323
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Both self-reported dietary information and urinary excretion have limitations in the assessment of phosphorus intake. We conducted a cross-sectional study to estimate dietary phosphorus intake by dietary records (DR) and 24-h urine collections (UC) and examined associated factors. SUBJECTS/METHOD...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0114-1
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Hyperhomocysteinemia (HHCY) is a risk factor for cardiovascular diseases (CVD). HHCY may interact with hypertension (HTEN) and an unfavorable cholesterol profile (UNFAVCHOL) to alter the risk of CVD. OBJECTIVES:To estimate the prevalences of HHCY (1) isolated and (2) in combination with UNFAVCHOL and/or HTE...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602097
更新日期:2005-04-01 00:00:00