Wavelength dependence of the precision of noninvasive optical measurement of oxy-, deoxy-, and total-hemoglobin concentration.

Abstract:

:The precision of noninvasive optical measurement of the concentration changes in oxy-, deoxy-, and total-hemoglobin depends on wavelength. For estimating the precision, we calculated the noise level of the concentration changes as the uncertainty in measurements using several wavelength pairs of light. Seven laser diodes (664-848 nm) were used simultaneously for spectroscopic measurement of brain activity during finger motor stimulation. We also used the analysis of error propagation from the uncertainty in direct measurements of absorbance changes to estimate indirectly the uncertainty of concentration changes. The measurement of the concentration changes made using an 830/664-nm pair are two times (oxy-Hb) and six times (deoxy-Hb) more precise than those made using an 830/782-nm pair.

journal_name

Med Phys

journal_title

Medical physics

authors

Yamashita Y,Maki A,Koizumi H

doi

10.1118/1.1373401

subject

Has Abstract

pub_date

2001-06-01 00:00:00

pages

1108-14

issue

6

eissn

0094-2405

issn

2473-4209

journal_volume

28

pub_type

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