The effects of supraceliac aortic clamping on the anticoagulant effects of heparin.

Abstract:

BACKGROUND:Coagulopathy is frequently encountered during supraceliac aortic clamping. Patients are routinely heparinized during these operations. This experiment was undertaken to evaluate the effect of supraceliac aortic cross-clamping (XC) on heparin pharmacodynamics. MATERIAL AND METHODS:Fourteen mongrel dogs were randomly divided into three groups: Group 1 (X; n = 6), 90 minutes aortic XC; Group 2 (SH; n = 4), sham operation and heparin, 100 mg/kg intravenously; and Group 3 (XH; n = 4), heparin, 100 mg/kg intravenously 3 minutes before XC. Prothrombin time (PT) and partial prothrombin time (PTT) were measured serially. Heparin concentrations were estimated via automated titration with protamine sulfate. RESULTS:After XC, PTT is increased during reperfusion. Heparin administration (XH) before aortic XC increases PTT above those with X or SH. Anticoagulation was potentiated and prolonged by XC. There was no difference in heparin concentration or PT. CONCLUSION:Supraceliac aortic clamping significantly affects heparin pharmacodynamics and may contribute to coagulopathy.

journal_name

Am J Surg

authors

Money SR,Ballinger BA,Crockett DE Jr,Chatman DM,Lohmann TP

doi

10.1016/S0002-9610(96)00140-7

subject

Has Abstract

pub_date

1996-08-01 00:00:00

pages

155-7

issue

2

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(96)00140-7

journal_volume

172

pub_type

杂志文章
  • Results of BCG adjuvant immunotherapy in 100 patients with epidermoid carcinoma of the head and neck.

    abstract::One hundred patients with advanced, recurrent, or metastatic squamous cell carcinoma of the head and neck were treated with chemotherapy and BCG as adjuvant immunotherapy. The overall response rate was 35 per cent, and the median duration of response was seventeen weeks. BCG does not prolong duration of remission or s...

    journal_title:American journal of surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0002-9610(77)90381-6

    authors: Suen JY,Richman SP,Livingston RB,Hersh EM,Craig R,Tonymon K

    更新日期:1977-10-01 00:00:00

  • Duodenum-preserving pancreatic head resection leads to relief of common bile duct stenosis.

    abstract:BACKGROUND:Common bile duct stenosis (CBDS) is one of the most frequent complications in chronic pancreatitis with inflammatory mass in the head of the pancreas (IMH). METHODS:A total of 474 patients who underwent duodenum-preserving pancreatic head resection (DPPHR) between 1982 and 1998 were reevaluated; 219 patient...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(01)00713-9

    authors: Schlosser W,Poch B,Beger HG

    更新日期:2002-01-01 00:00:00

  • Innovative introduction to surgery in the preclinical years.

    abstract:BACKGROUND:Lack of exposure to surgery in the preclinical years of medical school contributes to students' negative opinions of the field and to low application rates to categorical surgical programs. METHODS:Forty preclinical medical students attended a series of 16 seminars and practice sessions covering the gamut o...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2006.12.038

    authors: Riboh J,Curet M,Krummel T

    更新日期:2007-08-01 00:00:00

  • Common bile duct obstruction by hepatoma.

    abstract::Two cases of hepatoma are presented in which the clinical manifestations of biliary obstruction resulted from growth of hepatoma into the extrahepatic bile duct. Recognition of such a manifestation of the hepatoma may allow for surgical extirpation of the tumor combined with radiation therapy, which may result in long...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(77)90088-5

    authors: Kuroyanagi Y,Sawada M,Hidemura R,Aoki S,Kato H

    更新日期:1977-02-01 00:00:00

  • The correlation between fundamental characteristics and first-time performance in laparoscopic tasks.

    abstract:BACKGROUND:The ability of characteristics to predict first time performance in laparoscopic tasks is not well described. Videogame experience predicts positive performance in laparoscopic experiences but its mechanism and confounding-association with aptitude remains to be elucidated. This study sought to evaluate for ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2017.04.015

    authors: Harrington CM,Bresler R,Ryan D,Dicker P,Traynor O,Kavanagh DO

    更新日期:2018-04-01 00:00:00

  • Five hundred open taps or lavages in patients with abdominal stab wounds.

    abstract::From 1980 to 1984, 500 asymptomatic patients with anterior abdominal stab wounds found to have penetrated the anterior peritoneal cavity on local wound exploration in the emergency center were evaluated by the technique of open peritoneal tap, quantitative diagnostic peritoneal lavage, or both. The technique was found...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(84)90435-5

    authors: Feliciano DV,Bitondo CG,Steed G,Mattox KL,Burch JM,Jordan GL Jr

    更新日期:1984-12-01 00:00:00

  • Natural history of the leg amputee.

    abstract::For 173 patients undergoing major leg amputations, the operative mortality was 13 per cent. The ratio of below-knee (BK) to above-knee (AK) amputations was approximately unity. Of the 150 patients who survived amputation, 93 were given prostheses. Amoung the latter group, 76 per cent of the unilateral AK amputees and ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(77)90133-7

    authors: Couch NP,David JK,Tilney NL,Crane C

    更新日期:1977-04-01 00:00:00

  • Successful management of miliary tuberculosis after renal transplantation.

    abstract::Miliary tuberculosis is the most lethal form of tubercular disease. If dissemination of tubercle bacilli occurs without therapy, death is almost certain. The importance of establishing an etiologic diagnosis as promptly as possible in patients receiving immunosuppressive therapy is self-explanatory. The presence of a ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(75)90402-x

    authors: Rattazzi LC,Simmons RL,Spanos PK,Bradford DS,Najarian JS

    更新日期:1975-09-01 00:00:00

  • Omeprazole is more effective than a histamine H2-receptor blocker for maintaining a persistent elevation of gastric pH after colon resection for cancer.

    abstract:BACKGROUND:An assessment was made of the change and the effect of a histamine H(2)-receptor blocker (H(2)-blocker) or omeprazole on gastric pH after surgery. METHODS:Eighty patients who underwent colon resection for colorectal cancer were divided into groups of 20. Group I received neither H(2)-blocker nor omeprazole....

    journal_title:American journal of surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.amjsurg.2002.10.002

    authors: Hsu TC,Su CF,Leu SC,Huang PC,Wang TE,Chu CH

    更新日期:2004-01-01 00:00:00

  • Teaching and learning in the operating room is a two-way street: resident perceptions.

    abstract:BACKGROUND:The transformation of a trainee into a surgeon is influenced strongly by communication patterns in the operating room (OR). In the current era of limited educational opportunities, elucidation of teaching and learning strategies in this environment is critical. The aim of this study was to further understand...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2008.01.004

    authors: Vikis EA,Mihalynuk TV,Pratt DD,Sidhu RS

    更新日期:2008-05-01 00:00:00

  • Colorectal cancer surgery in the elderly: acceptable morbidity?

    abstract:BACKGROUND:Because of the increase in the geriatric population, an increasing number of elderly patients are being treated for colorectal cancer. The purpose of this study was to evaluate perioperative morbidity and mortality in this population. METHODS:A retrospective chart review was performed for patients 80 years ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2007.12.022

    authors: Ong ES,Alassas M,Dunn KB,Rajput A

    更新日期:2008-03-01 00:00:00

  • Transgenic introduction of androgen receptor into estrogen-receptor-, progesterone-receptor-, and androgen-receptor-negative breast cancer cells renders them responsive to hormonal manipulation.

    abstract:BACKGROUND:Estrogen-receptor (ER)-, progesterone-receptor (PR)-, and androgen-receptor (AR)-negative breast cancer cells are unaffected by treatment with dehydroepiandrosterone-sulfate (DHEAS) and an aromatase inhibitor (AI). We hypothesized that cell growth would be inhibited with DHEAS/AI treatment after successful t...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2006.02.004

    authors: Garreau JR,Muller P,Pommier R,Pommier S

    更新日期:2006-05-01 00:00:00

  • Pancreaticoduodenectomy for malignant pancreatic and periampullary neoplasms in elderly patients.

    abstract::Forty-two patients (age range: 70 to 86 years) underwent pancreaticoduodenectomy between 1970 and 1990 for carcinomas of the pancreas (23), ampulla (8), common bile duct (5), duodenum (5), or islet cells (1). After resection, reconstruction was done by either pancreaticojejunostomy (13) or pancreaticogastrostomy (25);...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(91)90104-l

    authors: Delcore R,Thomas JH,Hermreck AS

    更新日期:1991-12-01 00:00:00

  • Skin level permanent feeding gastrostomy.

    abstract::Feeding gastrostomy can be troublesome, inconvenient and painful to the patient, especially if the catheter is redundant, thereby causing deformity of the opening ad leakage of gastric juice and food around the tube. A skin level permanent feeding gastrostomy was fashioned in four patients with neurologic disease. The...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(81)90205-1

    authors: Cohen OM,Donner Y,Berlatzky Y

    更新日期:1981-03-01 00:00:00

  • Debt and other influences on career choices among surgical and primary care residents in a community-based hospital system.

    abstract:BACKGROUND:To evaluate debt and other factors that help formulate the career paths of future surgical and primary care physicians, a survey was undertaken. METHODS:Surgical specialty (SS) and primary care (PC) residents were surveyed regarding demographics, factors influencing choice of specialty, methods of financing...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(00)00543-2

    authors: Woodworth PA,Chang FC,Helmer SD

    更新日期:2000-12-01 00:00:00

  • Management of laryngotracheal trauma.

    abstract::Blunt trauma to the neck requires a systematic analysis of the laryngotrachea, the esophagus and the cervical spine in addition to general trauma considerations. Acute airway decompensation is best managed by tracheotomy, although if the situation permits, an orderly physical examination including indirect laryngoscop...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(81)90132-x

    authors: Sofferman RA

    更新日期:1981-04-01 00:00:00

  • Service through surgery: A quasi-experimental comparison study on the impact of a preclinical seminar course on diverse mentorship and attitudes towards the underserved.

    abstract:BACKGROUND:Increased surgical workforce diversity diminishes health disparities. METHODS:Researchers recruited and nonrandomly enrolled participants into intervention and comparison groups for a quasi-experimental study of the impact of a seminar course on student exposure to diverse mentorship and service through sur...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2019.07.031

    authors: Steinberg JR,Bryant TS,Carroll AL,Marin-Nevarez P,Lee EW,Anderson TN,Merrell SB,Lau JN

    更新日期:2020-06-01 00:00:00

  • The utility of routine preoperative computed tomography scanning in the management of veterans with colon cancer.

    abstract:BACKGROUND:The aim of this study is to assess the clinical utility of routine preoperative computed tomography (CT) scanning in patients with cancer of the intraperitoneal colon. METHODS:From November 1997 to June 2001, all patients at VA Puget Sound Healthcare System with a diagnosis of colon cancer were referred for...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(02)00841-3

    authors: Barton JB,Langdale LA,Cummins JS,Stelzner M,Lynge DC,Mock CN,Nason KS,Billingsley KG

    更新日期:2002-05-01 00:00:00

  • Thyroid cancer: some basic considerations.

    abstract::From these data and data from the literature, our recommended treatment for well-differentiated cancer is as follows: For papillary cancer, resection should be adequate to encompass the entire tumor, which in most cases would be complete lobectomy and possibly isthmusectomy. Prophylactic neck dissection is of no value...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(81)90378-0

    authors: Wanebo HJ,Andrews W,Kaiser DL

    更新日期:1981-10-01 00:00:00

  • Improving the feasibility and utility of OpTrust-A tool assessing intraoperative entrustment.

    abstract:BACKGROUND:Changes in the surgical training landscape have sparked an interest in developing new educational models anchored on entrustment assessment. We sought to optimize the validated OpTrust entrustment assessment tool by comparing ratings from short-course video reviews to previously validated intraoperative asse...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2017.10.036

    authors: Nikolian VC,Sutzko DC,Georgoff PE,Matusko N,Boniakowski A,Prabhu K,Church JT,Thompson-Burdine J,Minter RM,Sandhu G

    更新日期:2018-07-01 00:00:00

  • The effect of multidisciplinary teams for rectal cancer on delivery of care and patient outcome: has the use of multidisciplinary teams for rectal cancer affected the utilization of available resources, proportion of patients meeting the standard of care,

    abstract:BACKGROUND:We hypothesized that mandatory multidisciplinary team (MDT) participation improves process evaluation, outcomes, and technical aspects of surgery for rectal cancer in a stable practice of colorectal surgery. METHODS:A retrospective review of MDT data was conducted of all patients with colorectal cancer sinc...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2015.08.015

    authors: Richardson B,Preskitt J,Lichliter W,Peschka S,Carmack S,de Prisco G,Fleshman J

    更新日期:2016-01-01 00:00:00

  • Radioimmunoguided surgery in primary colorectal carcinoma: an intraoperative prognostic tool and adjuvant to traditional staging.

    abstract:BACKGROUND:The prognostic value of traditional staging classification for colorectal cancer has changed little since Dukes created the first staging scheme. Some patients with known metastatic disease are long-term survivors, while other patients with local disease die early. New intraoperative cancer detection technol...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(99)80295-5

    authors: Arnold MW,Young DC,Hitchcock CL,Schneebaum S,Martin EW Jr

    更新日期:1995-10-01 00:00:00

  • Laparoscopic treatment using an argon beam coagulator for nonparasitic liver cysts.

    abstract:BACKGROUND:Laparoscopic deroofing has been shown to produce good patient satisfaction and to have results similar to those of open surgical techniques. We evaluated the feasibility and efficacy of laparoscopic deroofing using an argon beam coagulator (ABC) in the patients with nonparasitic liver cysts. METHODS:Laparos...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(02)01361-2

    authors: Kwon AH,Matsui Y,Inui H,Imamura A,Kamiyama Y

    更新日期:2003-03-01 00:00:00

  • Clinical management of occult hemothorax: a prospective study of 81 patients.

    abstract:BACKGROUND:Intrapleural blood detected by computed tomography scan, but not evident on plain chest radiograph, defines occult hemothorax. This study determined the role for tube thoracostomy. METHODS:Hemothorax was quantified on computed tomography by measuring the deepest lamellar fluid stripe at the most dependent p...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2010.04.017

    authors: Mahmood I,Abdelrahman H,Al-Hassani A,Nabir S,Sebastian M,Maull K

    更新日期:2011-06-01 00:00:00

  • Surgical management of total carotid artery occlusion. An update.

    abstract::Fourteen operations were performed in 13 patients with total carotid artery occlusion. All patients had symptoms ranging in duration from a few hours to several months. Flow wa reestablished in 10 of the 14 arteries operated on, a success rate of 74 percent. Complication included one operative death and one permanent ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(80)90366-9

    authors: Hunt DG,Wheeler CG,Bukhari HI,Hempel GK

    更新日期:1980-05-01 00:00:00

  • Vascular ultrasonography prior to dialysis access surgery.

    abstract:BACKGROUND:Native arterial venous fistulas (NAVF) are generally considered preferable to synthetic grafts for chronic dialysis access. As increasing numbers of diabetic and elderly patients are treated, adequate NAVFs become more difficult to establish. Vascular ultrasonography (US) prior to NAVF surgery has received l...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(02)01103-0

    authors: Parmley MC,Broughan TA,Jennings WC

    更新日期:2002-12-01 00:00:00

  • Effect of cyclosporin A on hepatocyte proliferation after partial hepatectomy in rats: comparison with standard immunosuppressive agents.

    abstract::The effects of cyclosporin A on the regenerating liver were studied in rats after partial hepatectomy and were compared with those of conventional immunosuppressants such as methylprednisolone and azathioprine. In Group I, a standard hepatectomy removing two thirds of the organ was performed. In Group II, an oral dose...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(88)80705-0

    authors: Kim YI,Salvini P,Auxilia F,Calne RY

    更新日期:1988-02-01 00:00:00

  • Advanced squamous cell carcinoma of the maxillary sinus. Results of combined regional infusion chemotherapy, radiation therapy and surgery.

    abstract::Sequential intraarterial chemotherapy using bleomycin and methotrexate followed by high dose radiation and surgery was evaluated in 10 patients with stage III and IV squamous carcinomas of the maxillary sinus. Seven of 10 patients had extensive tumor necrosis in the surgical specimen, and no evidence of residual tumor...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(81)90037-4

    authors: Moseley HS,Thomas LR,Everts EC,Stevens KR,Ireland KM

    更新日期:1981-05-01 00:00:00

  • Sponsoring surgeons: An investigation on the influence of the da Vinci robot.

    abstract:INTRODUCTION:The integrity of the medical literature about robotic surgery remains unclear despite wide-spread adoption. We sought to determine if payment from Intuitive Surgical Incorporated (ISI) affected quality of the research produced by surgeons. METHODS:Publicly available financial data from the CMS website reg...

    journal_title:American journal of surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.amjsurg.2017.08.017

    authors: Criss CN,Gadepalli SK

    更新日期:2018-07-01 00:00:00

  • A safe and reliable technique for visualization of the laryngeal recurrent nerves in the neck.

    abstract:BACKGROUND:The risk of an injury of the laryngeal recurrent nerve is an important issue during any surgical procedure in the lower neck. METHODS:Based on our experience with the transcervical-subxiphoid bilateral videothoracoscopic maximal thymectomies, we developed an original technique of visualization for both of t...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2004.08.064

    authors: Zieliński M,Kuzdzał J,Szlubowski A,Soja J

    更新日期:2005-02-01 00:00:00