Interrelationship between glomerular filtration rate and renal transport of sodium and chloride during fetal life.

Abstract:

:The maturation of the glomerular filtration rate (GFR) and the interrelationship between the GFR and the renal transport of sodium and chloride have been evaluated during the last trimester of gestation with the use of long-term experiments in fetal lambs. An increase in GFR (milliliters per minute) parallel to the increase in fetal body weight was demonstrated; however, no significant change was shown when the GFR (milliliters per minute per kilogram of fetal body weight) (1.141 +/- 0.079) was related to fetal body weight or gestational age. There was a constant increase in sodium and chloride reabsorption (microequivalents per minute) during the last third of gestation. This increase in sodium and chloride reabsorption was less than the increase in GFR (milliliters per minute) before 129 days but became higher than the rise of GFR (milliliters per minute) after 129 days of gestation.

journal_name

Am J Obstet Gynecol

authors

Robillard JE,Sessions C,Kennedey RL,Hamel-Robillard L,Smith FG Jr

doi

10.1016/0002-9378(77)90712-8

subject

Has Abstract

pub_date

1977-08-01 00:00:00

pages

727-34

issue

7

eissn

0002-9378

issn

1097-6868

pii

0002-9378(77)90712-8

journal_volume

128

pub_type

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