A novel WT1 gene mutation associated with wilms' tumor and congenital male genitourinary malformation.

abstract：:The neonate conserves sodium avidly, and sodium intake is normally limited to that present in maternal milk. To evaluate the role of atrial natriuretic peptide (ANP) in this adaptation, preweaned rat pups were artificially reared and fed a formula with either normal sodium (25 mEq/L) or high sodium (145 mEq/L) for 7-8...

journal_title：Pediatric research

authors： Chevalier RL,Muchant DG,Thornhill BA,Belmonte DC,Pence RA,Baertschi AJ

更新日期：1996-08-01 00:00:00

abstract：:A longitudinal study describes the pattern of appearance of eight primitive reflexes in a population of 47 viable extremely premature infants, beginning as early as 25 wk postconceptional age (PCA). Infants were examined weekly, from 1 wk of age until discharge from the neonatal intensive care unit. Primitive reflexes...

journal_title：Pediatric research

authors： Allen MC,Capute AJ

更新日期：1986-12-01 00:00:00

abstract：:Extracellular glutathione peroxidase (E-GPx) is a selenoenzyme that reduces hydrogen peroxide and organic peroxides. All plasma glutathione peroxidase (GPx) activity in humans is attributable to E-GPx. The gastrointestinal (GI) tract also synthesizes and secretes E-GPx into the extracellular milieu. Endogenously gener...

journal_title：Pediatric research

authors： Tham DM,Whitin JC,Cohen HJ

更新日期：2002-05-01 00:00:00

abstract：:The effect of Cis-platin on the glomerular filtration rate and effective renal plasma flow was determined using a radioisotope clearance technique in young (3 wk old) and adult (more than 12 wk old) rats. Cis-platin was administered intravenously in dosages ranging from 2.5 to 10 mg/kg body weight, either as a single ...

journal_title：Pediatric research

authors： Jongejan HT,Provoost AP,Wolff ED,Molenaar JC

更新日期：1986-01-01 00:00:00

abstract：:Indomethacin is used to constrict the patent ductus arteriosus in premature infants. To clarify possible prostanoid receptor antagonists that can constrict the ductus, we studied in vivo constriction of the fetal and neonatal ductus arteriosus by AE3-208, a prostanoid EP4-receptor antagonist, in rats. Following quick ...

journal_title：Pediatric research

authors： Momma K,Toyoshima K,Takeuchi D,Imamura S,Nakanishi T

更新日期：2005-11-01 00:00:00

abstract：:Low IGF-I levels are found in patients with chronic liver disease, but it is not known whether these reductions in IGF-I are secondary to hepatic dysfunction or to malnutrition. To determine whether malnutrition associated with hepatic dysfunction causes the decrease in these levels, serum and liver IGF-I concentratio...

journal_title：Pediatric research

authors： Descos BP,Berry SA,Sharp HL,Gross CR,Weisdorf SA,Pescovitz OH

更新日期：1989-11-01 00:00:00

abstract：:Rats were fed a 50% galactose diet during pregnancy and nursing, and the testes were later examined and hormone levels determined in male offspring. Exposure to galactose for various periods during pregnancy, throughout the entire gestation, or postnatally to nursing mother until pups were 5 wk of age produced no sign...

journal_title：Pediatric research

authors： Chen YT,Mattison DR,Bercu BB,Schulman JD

更新日期：1984-04-01 00:00:00

abstract：:Carbon monoxide (CO) and the excitatory amino acid glutamate both dilate cerebral arterioles in newborn pigs. The key enzyme in CO synthesis is heme oxygenase, which is highly expressed in neurons with glutamatergic receptor activity as well as cerebral microvessels. During seizures the extracellular level of glutamat...

journal_title：Pediatric research

authors： Pourcyrous M,Bada HS,Parfenova H,Daley ML,Korones SB,Leffler CW

更新日期：2002-05-01 00:00:00

abstract：:Deficient quantity of amniotic fluid causes fetal guinea pig lung hypoplasia. Oligohydramnios that lasts only 5 days in early gestation is sufficient to reduce fetal lung growth significantly. We quantitated lung structural alterations at 50 days gestation (term is 67 days) of fetal guinea pigs whose amniotic fluid wa...

journal_title：Pediatric research

authors： Collins MH,Moessinger AC,Kleinerman J,James LS,Blanc WA

更新日期：1986-10-01 00:00:00

abstract：:Lung development progresses through a process reliant on mechanical cell stretch. However, this process is not well defined at the molecular level. Our goal was to globally analyze the transcriptome of fetal mouse lungs following short periods of tracheal occlusion (TO) to identify cellular processes that are rapidly ...

journal_title：Pediatric research

authors： Seaborn T,St-Amand J,Cloutier M,Tremblay MG,Maltais F,Dinel S,Moulin V,Khan PA,Piedboeuf B

更新日期：2008-02-01 00:00:00

abstract：:The ability of intravenously administered glucose or glucose oligosaccharides to supply 12% of the energy requirement of the growing miniature pig was determined. All pigs were fed a stock diet from days 5-28 of life, and a central venous catheter was inserted at 29 days. For the next 30 days, all pigs were fed both e...

journal_title：Pediatric research

authors： Andersen DW,Filer LJ Jr,Wu-Rideout YC,White LB,Stegink LD

更新日期：1982-04-01 00:00:00

abstract：:The fetal inflammatory response has been suggested as causal in neonatal morbidity. Serial levels of circulating cytokines were evaluated in 74 infants with a mean gestational age (GA) of 27.1 wk. Pro-inflammatory [tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), IL-1 beta, IL-2, IL-6, IL-8, IL-1...

journal_title：Pediatric research

authors： Hansen-Pupp I,Harling S,Berg AC,Cilio C,Hellström-Westas L,Ley D

更新日期：2005-11-01 00:00:00

abstract：:To determine the pathophysiologic significance of pertussis toxin (PT) on the human beta-adrenergic system, beta-adrenoceptor (beta-R)-density and cyclic AMP response of peripheral mononuclear blood cells (MN leukocytes) were studied in children during the paroxysmal stage of natural pertussis infection, after vaccina...

journal_title：Pediatric research

authors： Griese M,Sideropoulou O,Reinhardt D

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Genome-wide association studies have identified rs314276, rs314263, rs7759938, and rs314280 in or near the LIN28B gene as associated with age at menarche. To date, the effect of polymorphisms in this gene on idiopathic central precocious puberty (ICPP) in Chinese girls have not been reported. The aim of this...

journal_title：Pediatric research

authors： Hu Z,Chen R,Cai C

更新日期：2016-10-01 00:00:00

abstract：:Necrotizing enterocolitis (NEC) remains among the most common and devastating diseases in neonates. Despite advances in neonatal clinical care, specific treatment strategies and diagnostic modalities remain lacking. As a result, morbidity and mortality remain high. Improved understanding of the pathogenesis of NEC has...

journal_title：Pediatric research

authors： Shelby RD,Raab R,Besner GE,McElroy SJ

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Genotyping tests were developed to attenuate the impact of viral resistance. Information about the efficacy in genotype base antiretroviral therapy in children is rare and even more in low- and middle-income countries. METHODS:Sixteen children with antiretroviral therapy (ART) failure and triple-class drug-...

journal_title：Pediatric research

authors： Huerta-García G,Vazquez-Rosales JG,Mata-Marín JA,Peregrino-Bejarano L,Flores-Ruiz E,Solórzano-Santos F

更新日期：2016-07-01 00:00:00

abstract：:Data are scarce regarding mineral bioavailability from human milk in older infants who may also be receiving solid foods (beikost). We measured the absorption of Ca, Zn, and Fe in 14 healthy, nonanemic 5-7-mo-old breast-fed infants whose mothers milk was extrinsically labeled with stable isotopes (44Ca, 70Zn, and 58Fe...

journal_title：Pediatric research

authors： Abrams SA,Wen J,Stuff JE

更新日期：1997-03-01 00:00:00

abstract：:We analyzed by means of immunoblot technique the patterns of antibodies binding to polypeptides of Borrelia burgdorferi B31 in the sera of 21 children with different stages of Lyme disease. All sera but one recognized the flagellar protein 41 kD and all but two the 83-kD protein. The number of proteins recognized rose...

journal_title：Pediatric research

authors： Nadal D,Taverna C,Hitzig WH

更新日期：1989-10-01 00:00:00

abstract：:The regionalization of pediatric services has resulted in differential access to care, sometimes creating barriers to those living in underserved, rural communities. These disparities in access contribute to inferior healthcare outcomes among infants and children. We review the medical literature on telemedicine and i...

journal_title：Pediatric research

authors： Marcin JP,Shaikh U,Steinhorn RH

更新日期：2016-01-01 00:00:00

abstract：:Growth hormone (GH) regulates growth and development in the postnatal period but lacks somatotropic activity in the fetus. In contrast, the placental hormone placental lactogen (PL) stimulates amino acid transport, DNA synthesis, and somatomedin production in isolated fetal tissues, suggesting that PL may function as ...

journal_title：Pediatric research

authors： Fowlkes J,Freemark M

更新日期：1992-08-01 00:00:00

abstract：:To investigate the role of nutrition in the regulation of IGFs during the perinatal period, 10-d-old rats were infused intravenously with various concentrations of nutrients for 24 h. Breast-fed litter mates served as controls. The effect of caloric intake on concentrations of IGF-I and IGF-II as well as IGF-binding p...

journal_title：Pediatric research

authors： Philipps A,Drakenberg K,Persson B,Sjögren B,Eklöf AC,Hall K,Sara V

更新日期：1989-08-01 00:00:00

abstract：:Vitamin A and its precursor beta-carotene are naturally occurring antioxidants. The effects of diets deficient in beta-carotene and vitamin A on the alveolar-capillary membrane were studied in young adult BALB/C mice before and after exposure to 65% oxygen. One of three diets (standard complete, beta-carotene deficien...

journal_title：Pediatric research

authors： Cohen-Addad N,Bollinger R,Chou J,Poland R

更新日期：1988-01-01 00:00:00

abstract：:Surface active aerosols were produced from aqueous dispersions of mixed lipids (CLL), extracted from bovine lung lavage. Particle size distributions were measured as a function of humidity for two types of aerosol generators: ultrasonic and jet. Lipid dispersions before aerosolization were prepared by sonication in an...

journal_title：Pediatric research

authors： Marks LB,Notter RH,Oberdorster G,McBride JT

更新日期：1983-09-01 00:00:00

abstract：:To study the course of regional metabolite concentrations during early brain development, we measured in vivo metabolites [N-acetyl-aspartate (NAA), choline-containing compounds, and myoinositol (M-Ino)] in the precentral area of the cerebrum by short echo-time single volume proton magnetic resonance spectroscopy and ...

journal_title：Pediatric research

authors： Hüppi PS,Fusch C,Boesch C,Burri R,Bossi E,Amato M,Herschkowitz N

更新日期：1995-02-01 00:00:00

abstract：:The effects of early protein-deficiency on lung development were studied in the rat. Newborn male rats were nursed in groups of eight. Control dams and pups received a 15% protein diet during the whole experiment. Test mothers only received 12 and 8% proteins from the 7th and the 14th day of lactation. Test rats fed a...

journal_title：Pediatric research

authors： Kalenga M,Henquin JC

更新日期：1987-07-01 00:00:00

abstract：:BACKGROUNDLow birth weight is associated with childhood stunting, but equivalent associations for birth body composition (BC) remain unknown. The aim of this study was to assess associations between birth BC and height-for-age z-score (HAZ) at 2 years of age.METHODSIn a prospective cohort study, fat mass (FM) and fat-...

journal_title：Pediatric research

authors： Admassu B,Wells JCK,Girma T,Andersen GS,Owino V,Belachew T,Michaelsen KF,Abera M,Wibaek R,Friis H,Kæstel P

更新日期：2017-08-01 00:00:00

abstract：:Chronic disease risk is inextricably linked to our early-life environment, where maternal, fetal, and childhood factors predict disease risk later in life. Currently, maternal obesity is a key predictor of childhood obesity and metabolic complications in adulthood. Although the mechanisms are unclear, new and emerging...

journal_title：Pediatric research

authors： Gohir W,Ratcliffe EM,Sloboda DM

更新日期：2015-01-01 00:00:00

abstract：:Monocyte chemoattractant protein-1 (MCP-1), acting through its C-C chemokine receptor 2 (CCR-2), has important roles in inflammation, angiogenesis, and wound repair. The individual and combined effects of inhaled nitric oxide (NO) and hyperoxia on lung MCP-1 and CCR-2 in relation to lung leukocyte dynamics are unknown...

journal_title：Pediatric research

authors： Ekekezie II,Thibeault DW,Garola RE,Truog WE

更新日期：2001-11-01 00:00:00

abstract：:Newborn rats exposed to 60% O(2) for 14 d demonstrated a bronchopulmonary dysplasia-like lung morphology and pulmonary hypertension. A 21-aminosteroid antioxidant, U74389G, attenuated both pulmonary hypertension and macrophage accumulation in the O(2)-exposed lungs. To determine whether macrophage accumulation played ...

journal_title：Pediatric research

authors： Jankov RP,Luo X,Belcastro R,Copland I,Frndova H,Lye SJ,Hoidal JR,Post M,Tanswell AK

更新日期：2001-08-01 00:00:00

abstract：:Exposure of neonatal rats to > or = 95% O2 for 2 wk, a widely used model of oxidant/antioxidant interactions in neonatal lung injury, results in arrested lung growth without the dysplastic lesions observed in chronic human neonatal lung injury. To determine whether dysplastic lung cell growth would be seen at lesser O...

journal_title：Pediatric research

authors： Han RN,Buch S,Tseu I,Young J,Christie NA,Frndova H,Lye SJ,Post M,Tanswell AK

更新日期：1996-06-01 00:00:00