Abstract：
:Serotonin was introduced, by means of a fine cannula, into the lateral geniculate body of cats immobilized with Flaxedil and artificially ventilated, while the electrical activity at the point of injection was monitored by means of microelectrodes. Doses of 1.25 to 30 mug dissolved in 0.5 to 2.0 mul of saline produced, in 2-30 min, changes in electrical activity characteristic of synchronization: increase in the rhythmicity and in the amplitude of the spontaneous gross waves and increase in the clustering of the spontaneous neuronal action potentials. At the same time the activity of neurons which produced action potentials of high amplitudes was decreased, the activity of neurons which produced action potentials of low amplitudes was increased. Action potentials of different amplitudes were produced, in this case, by neurons of different types. Thus, in the lateral geniculate as in other thalamic nuclei studied in previous investigations, the synchronization of spontaneous activity seems to require the simultaneous excitation and inhibition of two different types of neurons. The action of serotonin on activity evoked by stimulation with brief flashes of light was limited to the decrease in the amplitude of the average gross response and the inhibition of only one type of neuron. This suggests that, in the lateral geniculate body, serotonin may be implicated in different ways in the different network structures responsible for the development of spontaneous as contrasted with evoked activity.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Rinaldi P,Sutko M,Mahnke JH,Verzeano Mdoi
10.1016/0031-9384(75)90148-1subject
Has Abstractpub_date
1975-01-01 00:00:00pages
95-102issue
1eissn
0031-9384issn
1873-507Xpii
0031-9384(75)90148-1journal_volume
14pub_type
杂志文章abstract：BACKGROUND:Studies evaluating the efficacy of anti-inflammatory treatment strategies for major depressive disorder (MDD) commonly include participants who do not demonstrate elevated concentrations of baseline inflammatory mediators, or simply fail to assess baseline inflammation. This may result in an underestimation ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.05.006
更新日期：2019-08-01 00:00:00
abstract：:The area postrema (AP), located in the caudal hindbrain, is one of the primary binding sites for the endocrine satiation hormone amylin. Amylin is co-secreted with insulin from pancreatic ß-cells and binds to heterodimeric receptors that consist of a calcitonin core receptor (CTR) paired with receptor-activity modifyi...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2020.112992
更新日期：2020-09-01 00:00:00
abstract：:When estrous female rats regulate or pace (P) the timing of vaginal intromissions received from males during mating, the stimulation is more effective in inducing luteal function and abbreviating the period of receptivity than is nonpaced (NP) stimulation. The present studies examined whether the coital stimuli necess...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(89)90163-7
更新日期：1989-01-01 00:00:00
abstract：:Rats were trained to perform shuttle responses to a buzzer in four different situations: pseudoconditioning or D test (buzzers and footshocks presented at random), classical conditioning or DP test (buzzers and footshocks paired on every trial), avoidance without stimulus pairing or DC test (buzzer-shock intervals var...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(79)90128-8
更新日期：1979-07-01 00:00:00
abstract：:The food intakes of male and female rats (Harvard strain) adapted to cold (5 degrees C) starting at weaning were studied in the cold and during reacclimation to 25 degrees C. Following 24 hr food deprivation, the male rats regained the weight they had lost without making up for the food they had missed (increased food...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90377-8
更新日期：1982-07-01 00:00:00
abstract：:Less sensitive interoception for hunger and fullness has been observed in people who consume a diet rich in saturated fat and added sugar. In this study we examined whether healthy young people who routinely consume such diets, also demonstrate less sensitive thirst interoception. Participants, varying primarily in di...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.11.050
更新日期：2015-02-01 00:00:00
abstract：:An operant chamber has been developed for studying lever-press conditioning in the green crab Carcinus maenas. In one series of experiments, animals were presented with a single bar and were reinforced with food for every bar press. Performance increased over time and high rates of responding were observed after 2 day...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(90)90311-q
更新日期：1990-08-01 00:00:00
abstract：:Chronic stress during adolescence is related to increased prevalence of anxiety disorders and alcohol use disorders in humans. This phenotype has been consistently recapitulated in animal models with male subjects, but models using female subjects are fewer. The aim of these studies was to test the hypothesis that chr...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2017.02.010
更新日期：2017-05-01 00:00:00
abstract：:Six goldfish, Carassius auratus, weighing 2.5 to 4 g were placed individually in an aquarium with two communicating chambers. One chamber was thermostatted at 34 degrees C, the other at 37 degrees C. In control Session a, without external intervention, fish selected the cooler chamber most of the time and stayed only ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00444-7
更新日期：1998-02-01 00:00:00
abstract：:The odor of blood may have both aversive and attractive properties for mammals, depending on the species of the odor donor and the species perceiving the odor. To better understand the informational content of blood odor for a prey species we assessed behavioral responses of male CD-1 mice (n=60) to the odor of blood ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2017.12.006
更新日期：2018-02-01 00:00:00
abstract：:Male weanling Sprague-Dawley rats with dorsomedial hypothalamic lesions (DMNL rats) primarily destroying the dorosomedial hypothalamic nuclei (DMN) showed significant hypophagia on lab chow chunks compared to sham-operated controls. When given a choice between lab chow in the form of chunks or powder, both controls an...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(77)90326-2
更新日期：1977-08-01 00:00:00
abstract：:Rats were weaned early (Day 15), normally (Day 21) or late (Day 27). When they reached 200 g (+/- 10) they were placed into the activity-stress paradigm. Half the rats in each weaning group were housed in activity-wheel cages and fed only 1 hr each day. The remaining rats served as food-yoked home cage controls and we...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(85)90012-5
更新日期：1985-06-01 00:00:00
abstract：:Phencyclidine (PCP) treatment induces social withdrawal in the rat model of schizophrenia but little is known about the qualitative adequacy of behaviors displayed during interactions. Affiliative, avoidance, and aggressive behaviors were examined in rats 20 h after the 1st, the 8th, and the 15th injection of 10 mg/kg...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2008.11.002
更新日期：2009-03-02 00:00:00
abstract：:Data are presented which demonstrate the task generality of pituitary-adrenal changes that accompany avoidance conditioning. In two experiments a conditioned aversion to milk was established by pairing it with lithium chloride (LiCl). In Experiment 1 conditioned pituitary-adrenal activation occurred when, in a conflic...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(76)90006-8
更新日期：1976-12-01 00:00:00
abstract：:Light-dark box and open field are conventional tests for assessment of anxiety-like behavior in the laboratory mice, based on approach-avoidance conflict. However, except the basic principles, variations in the equipment and procedures are very common. Therefore, contribution of certain methodological issues in differ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.05.006
更新日期：2014-06-22 00:00:00
abstract：:Midbrain raphe lesions induced aggressive behavior which was characterized by defensive aggression rather than offensive aggression in nature. Furthermore, raphe-lesioned rats exhibited muricide. This muricide included not only mouse-killing but also mouse-eating behavior. Both dorsal and medial raphe lesioned (dm-R) ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(77)90166-4
更新日期：1977-07-01 00:00:00
abstract：:The present study aimed to evaluate the circadian rhythmicity of some physiological variables, including rectal temperature (RT), respiration rate (RR), heart rate (HR) and skin temperature (ST) in sheep during the summer and winter in semi-arid tropical environment. Eight Malpura rams of 3-4year of age with an averag...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2016.11.010
更新日期：2017-02-01 00:00:00
abstract：:Grooming and penile reflexes were studied in male rats that were restrained in supine position with the penile sheath retracted or were free to copulate with sexually receptive females. In Experiment 1 there was a reliable concordance in supine males between the tendency to groom and the tendency to display penile ref...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(88)90219-3
更新日期：1988-01-01 00:00:00
abstract：:The entrainment of circadian rhythms by light-dark (LD) cycles has been extensively investigated in laboratory studies. In almost all of these studies, organisms have not been allowed to modulate their exposure to the LD cycle. In the present study, the rhythm of running-wheel activity was investigated in nocturnal (d...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2004.03.015
更新日期：2004-09-15 00:00:00
abstract：:In experiment 1, electrical stimulation of the posterior hippocampus was shown to produce state-dependent learning (SDL) for a step-out inhibitory avoidance task in rats. Stimulation sites in either the right or left hippocampus were equally effective in producing this effect. Similarly, the presence or absence of aft...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(85)90091-5
更新日期：1985-01-01 00:00:00
abstract：:Kindled seizures can impair learning and memory. In the present study the effect of low-frequency electrical stimulation (LFS) on kindled seizure-induced impairment in spatial learning and memory was investigated and followed up to one month. Animals were kindled by electrical stimulation of hippocampal CA1 area in a ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2016.11.001
更新日期：2017-01-01 00:00:00
abstract：:Women were divided into those eating at a decelerated or linear rate. Eating rate was then experimentally increased or decreased by asking the women to adapt their rate of eating to curves presented on a computer screen and the effect on food intake and satiety was studied. Decelerated eaters were unable to eat at an ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2008.10.011
更新日期：2009-02-16 00:00:00
abstract：:Crib-biting in the horse is frequently prevented in the short-term by horse-owners using physical means. Because it has been proposed that crib-biting may function to reduce stress, the effect of prevention of crib-biting and/or eating on the behaviour, heart rate, and plasma cortisol and beta-endorphin concentrations...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(98)00070-5
更新日期：1998-08-01 00:00:00
abstract：:The effect of amylin injected IP on food intake in rats of different age (7-9 weeks, 3 months, 15-18 months) was investigated. The possible site of amylin action was investigated using vagotomized rats. Lastly, the influence of food composition on amylin's effect was investigated. In 12-h food-deprived old rats, food ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(94)90076-0
更新日期：1994-05-01 00:00:00
abstract：:Pigeons were exposed to complex fixed-ratio schedules to assess whether the temporal location of schedule-induced attack was controlled by the discriminative properties of food or by the aversive aftereffects of food withdrawal. When exposed to a multiple fixed-ratio 25 fixed-ratio N schedule in which either fixed-rat...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(85)90193-3
更新日期：1985-03-01 00:00:00
abstract：:We previously demonstrated that chronic dietary treatment with acarbose, an alpha-glucosidase inhibitor, improves glucose homeostasis in the streptozotocin (STZ)-induced diabetic rat. In this study we evaluated the effects of 4 weeks of acarbose treatment on glucose homeostasis in STZ-diabetic rats for both meal-fed (...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(98)00013-4
更新日期：1998-03-01 00:00:00
abstract：:The present study addressed the possible role of a conditioned taste aversion in the anorectic effect of bacterial lipopolysaccharide (LPS) in the rat. Pairing an intraperitoneal (IP) injection of LPS (100 micrograms/kg b.wt.) with the subsequent presentation of a familiar diet (FD) or of a novel-tasting saccharin die...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(93)90309-4
更新日期：1993-11-01 00:00:00
abstract：:We have designed software for an Apple II GS microcomputer allowing simultaneous on-line monitoring of blood glucose level and neuronal firing frequency in experimental rats. Blood glucose level in the carotid blood was continuously measured by a glucose analyzer and digitized through an A/D board. The firing rate of ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(93)90285-n
更新日期：1993-05-01 00:00:00
abstract：:Research investigating sodium hunger in mice has failed to produce evidence that mineralocorticoids are involved in sodium appetite. In our own laboratory, doses of deoxycorticosterone acetate (DOCA) ranging from 1 mg/kg to 20 mg/kg have failed to induce a sodium appetite. In rats, glucocorticoids have been effective ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(96)00247-8
更新日期：1996-11-01 00:00:00
abstract：:The amphibian tetradecapeptide bombesin (BN) decreases food intake in both humans and animals. Studies have typically examined the effects of BN on scheduled meals in deprived subjects. To investigate the properties of this peptide under more naturalistic conditions, we examined the effects of BN in spontaneously feed...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(95)02136-1
更新日期：1996-02-01 00:00:00
