Relationship between numbers of retinal ganglion cells and lateral geniculate neurons in the rhesus monkey.

Abstract:

:Studies of the numbers of retinal ganglion cells and lateral geniculate nucleus (LGN) neurons in primates suggest that the numbers of both types of neurons may vary over a two-fold range from one individual to another. This raises the question of whether the numbers of ganglion cells and LGN neurons are related or vary independently from individual to individual. We used stereological procedures to obtain unbiased estimates of the numbers of both cell types in seven rhesus monkeys. We found no significant correlation (rs = -0.21) between the numbers of retinal and LGN cells in the same animals. In agreement with previous studies, the average ratio of the number of retinal ganglion cells that project to the LGN and the number of LGN cells was approximately 1:1. However, this ratio varied over a two-fold range, from 0.78:1 to 1.64:1, in individual animals. These results have important implications for understanding the mechanisms of retino-geniculate development and for understanding the connectional wiring between the retina and LGN.

journal_name

Vis Neurosci

journal_title

Visual neuroscience

authors

Spear PD,Kim CB,Ahmad A,Tom BW

doi

10.1017/s0952523800007239

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

199-203

issue

1

eissn

0952-5238

issn

1469-8714

pii

S0952523800007239

journal_volume

13

pub_type

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