Antifertility effects of an LHRH agonist in male mice.

abstract：OBJECTIVE:To compare the effectiveness of outpatient medical abortion with mifepristone 200 mg and two misoprostol 800 mcg doses at 64-70 and 71-77 days of gestation. STUDY DESIGN:We conducted a retrospective chart review of medical abortion outcomes among clients with 64-77 day gestations at a Mexico City public clin...

journal_title：Contraception

authors： Dzuba IG,Castillo PW,Bousiéguez M,Lugo Hernández EM,Castañeda Vivar JJ,Sanhueza Smith P

更新日期：2020-08-01 00:00:00

abstract：:The metabolism of isotopically labeled ethinyl estradiol (EE) and mestranol (ME) was studied in 3 baboons before and after the simultaneous injection of a norethindrone-mestranol contraceptive formulation. 6 days after the administration of tritiated-EE and carbon-14-ME, the mean urinary excretion of labeled-EE was 3...

journal_title：Contraception

authors： Kulkarni BD,Avila TD,O'Leary JA

更新日期：1977-03-01 00:00:00

abstract：:The mechanism of action of intrauterine devices varies from one type of device to another, although the principle of action is the same, namely, to interfere with the physiology of reproduction at the endometrial level. The biochemical changes of the endometrial tissue and the composition of the uterine fluid have bee...

journal_title：Contraception

authors： Johannisson E

更新日期：1987-07-01 00:00:00

abstract：:In order to determine whether inhibition of the endometrial estradiol-17 beta-dehydrogenase activity by Cu++ could be one of the factors accounting for the enhanced contraceptive efficacy of copper intrauterine devices (Cu-IUD), the activity of the enzyme was measured in endometrial biopsies from women wearing this de...

journal_title：Contraception

authors： Tseng L,Dramusic V,Gurpide E

更新日期：1979-03-01 00:00:00

abstract：:The relationship between intrauterine device (IUD) use and the development of endometrial cancer was assessed in data from seven countries that were collected between 1979 and 1988 for a multinational hospital-based case-control study. Two hundred twenty-six cases of endometrial cancer were compared with 1,529 control...

journal_title：Contraception

authors： Rosenblatt KA,Thomas DB

更新日期：1996-12-01 00:00:00

abstract：:A morphometric study was undertaken to quantitate vessel numbers in uterine biopsies from a control group of patients, patients with dysfunctional uterine bleeding and patients taking low dose norethisterone or levonorgestrel. Vessels were counted at the endometrial/myometrial junction and in the functional endometriu...

journal_title：Contraception

authors： Hourihan HM,Sheppard BL,Bonnar J

更新日期：1986-12-01 00:00:00

abstract：:The requirement that every woman desiring medical abortion must come in person to a clinical facility to obtain the drugs is a substantial barrier for many women. To eliminate this requirement in the United States, two key components of the standard initial visit would need to be restructured. First, alternatives to u...

journal_title：Contraception

authors： Raymond EG,Grossman D,Wiebe E,Winikoff B

更新日期：2015-09-01 00:00:00

abstract：:The rheological properties of four commercially available spermicidal gels (two polyacrylic acid derivatives and two carboxymethylcellulose based) and their dilutions with a vaginal fluid simulant (pH 4.2) and a semen simulant (pH 7.7) were measured at 25 degrees C and 37 degrees C over a biologically relevant range o...

journal_title：Contraception

authors： Owen DH,Peters JJ,Lavine ML,Katz DF

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Determining medical abortion outcome commonly includes a costly evaluation such as ultrasonography or serial serum hCG testing. Urine pregnancy testing may represent a less costly alternative. METHODS:This prospective diagnostic test evaluation study was part of a multisite randomized trial of 1080 women un...

journal_title：Contraception

authors： Godfrey EM,Anderson A,Fielding SL,Meyn L,Creinin MD

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:The use of progestogen-only contraceptives by breastfeeding women raises theoretical concerns regarding possible adverse effects on breastfeeding success, and infant health or growth. This review was conducted to determine from the literature whether use of progestogen-only contraceptives by breastfeeding wo...

journal_title：Contraception

authors： Kapp N,Curtis K,Nanda K

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:Limitations on didactic time pose barriers to teaching non-directive pregnancy options counseling. This study set out to explore the use of an online module to support trainee performance in a pregnancy options counseling standardized-patient exercise implemented among third-year medical students, and to exam...

journal_title：Contraception

authors： Lupi C,Ward-Peterson M,Chang W

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:Our objective was to compare continuation and complication rates of subdermal etonogestrel implants and intrauterine devices (IUDs) using Medicaid insurance claims. STUDY DESIGN:We performed a retrospective cohort study using insurance claims data for 15- to 44-year-old subjects receiving implants or IUDs fr...

journal_title：Contraception

authors： Romano MJ,Toye P,Patchen L

更新日期：2018-04-24 00:00:00

abstract：OBJECTIVES:Nurses play an integral role in intrapartum and postpartum patient education. This exploratory study aims to assess the attitudes, knowledge, and practices of labor and delivery and postpartum nurses regarding contraception and evaluate for changes in these measures 1 year after an institutional initiative a...

journal_title：Contraception

authors： Benfield N,Hawkins F,Ray L,McGowan A,Floyd K,Africa D,Barreto M,Levi E

更新日期：2018-05-01 00:00:00

abstract：:Community-based distribution (CBD) programs are the optimum way of reaching people in rural areas of developing countries where conventional methods of delivery do not exist or fail. This paper reviews findings and experiences from over 30 years of efforts to implement CBD of family planning methods around the world. ...

journal_title：Contraception

authors： Prata N,Vahidnia F,Potts M,Dries-Daffner I

更新日期：2005-12-01 00:00:00

abstract：:The pharmacokinetics and pharmacodynamic effects of two doses of norethisterone (5mg and 3mg) used as a 'visiting pill' were investigated. There were no significant differences in the pharmacokinetics of the two doses except for the peak concentration achieved and the bioavailability as assessed by the area under the ...

journal_title：Contraception

authors： Song S,Chen JK,Yang PJ,Cheng DH,Liu WY,Fotherby K

更新日期：1986-09-01 00:00:00

abstract：OBJECTIVES:To assess factors associated with pregnancy fatalism among U.S. adult women. STUDY DESIGN:I used data from the Change and Consistency in Contraceptive Use study, which collected information from a national sample of 4634 U.S. women aged 18-39 at baseline (59% response rate). I assessed pregnancy fatalism ba...

journal_title：Contraception

authors： Jones RK

更新日期：2018-10-01 00:00:00

abstract：:The influence of copper ions on myometrial activity was tested in nonpregnant rabbits in vitro and in vivo, and nonpregnant women in vivo. In an organ bath, CuCl2 in concentrations of 3 micro M and higher caused a dose-dependent increase in the contractile activity of isolated rabbit myometrium. In rabbits in vivo, in...

journal_title：Contraception

authors： Laundański T,Kobylec E,Akerlund M

更新日期：1981-08-01 00:00:00

abstract：:In Lebanon, coitus interruptus or withdrawal remains a widely practiced method of family planning. Our research sought to understand the role of men in reproductive health in Lebanon by focusing on this common practice. Our main questions were: Why is it that the practice persists when more effective modern methods of...

journal_title：Contraception

authors： Myntti C,Ballan A,Dewachi O,El-Kak F,Deeb ME

更新日期：2002-02-01 00:00:00

abstract：:Seventy-five women with a mean age of 27.5 years who requested Norplant implants for contraception were studied over a five-year period. The patients kept daily diaries of their vaginal bleeding and coital frequency, and were seen at least every six months at which time their weight was measured. This study examines t...

journal_title：Contraception

authors： Pasquale SA,Knuppel RA,Owens AG,Bachmann GA

更新日期：1994-08-01 00:00:00

abstract：:A study was conducted to evaluate the effect of NORPLANT use on hemoglobin levels (HB), packed cell volume (PCV) and menstrual bleeding patterns. NORPLANT insertions were performed on 50 healthy volunteers in Ilorin, Nigeria, between January-March 1986. Whole blood samples were collected at admission, 6-month and 12-m...

journal_title：Contraception

authors： Fakeye O,Balogh S

更新日期：1989-03-01 00:00:00

abstract：:The contraceptive efficacy of breastfeeding was assessed in 236 healthy urban women who were followed at monthly intervals during the first postpartum year. Proportional hazard models were used to evaluate the influence of time postpartum, menstrual status and breastfeeding pattern upon the risk of pregnancy. Time and...

journal_title：Contraception

authors： Díaz S,Aravena R,Cárdenas H,Casado ME,Miranda P,Schiappacasse V,Croxatto HB

更新日期：1991-04-01 00:00:00

abstract：:A multinational comparative trial of three IUDs (Copper 7, Lippes loop size D and the Postpartum T) randomly inserted immediately following delivery of the placenta was conducted in six centres. A total of 841 women entered the study. As the predetermined termination indices for expulsions were exceeded at six months ...

journal_title：Contraception

authors：

更新日期：1980-07-01 00:00:00

abstract：:The objectives of the study were to assess the ability of the Femcap, a new vaginal contraceptive device made of silicone and designed to fit snugly around the cervix to prevent the penetration of sperm into midcycle cervical mucus when used with and without spermicide; and to compare it with the standard contraceptiv...

journal_title：Contraception

authors： Mauck CK,Baker JM,Barr SP,Johanson W,Archer DF

更新日期：1997-08-01 00:00:00

abstract：:This study examined the effect of epostane, a new antifertility drug, on normal and hCG-stimulated progesterone production during the luteal phase of the menstrual cycle in rhesus monkeys. When administered once each day for five days, epostane inhibited normal luteal phase progesterone levels in a dose-related fashio...

journal_title：Contraception

authors： Snyder BW,Schane HP

更新日期：1985-05-01 00:00:00

abstract：:LHRH and three potent antagonistic analogs: z-[Gln1, des-His2,D-Pse6,des-Gly10]-LHRH ethylamide, where D-Pse = threo-D-phenylserine; z-[Gln1,des-His2,D-Phe6,des-Gly10]-LHRH ethylamide; and Boc-[Ser(Bzl)1,des-His2,D-Trp6]-LHRH; were studied for their effects on blood pressure and heart rate in chronically catheterized ...

journal_title：Contraception

authors： Smith RD,Edgren RA

更新日期：1982-04-01 00:00:00

abstract：OBJECTIVE:This pilot study investigates whether an educational handout could increase short-term information retention about drug interactions between antiepileptic drugs (AEDs) and hormonal contraceptives among female epilepsy patients of reproductive age. STUDY DESIGN:This is a pilot randomized controlled trial of a...

journal_title：Contraception

authors： Mody SK,Haunschild C,Farala JP,Honerkamp-Smith G,Hur V,Kansal L

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Medroxyprogesterone acetate (MPA), which increases high-density lipoprotein level, has not been used as a progestin in combination with estrogen in a transdermal patch to date. The aim of the research was to develop and evaluate a matrix-type transdermal drug delivery (TDD) system of a combination of ethinyl...

journal_title：Contraception

authors： Agrawal SS,Pruthi JK

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:To assess patterns of contraceptive use at last intercourse among women with physical or cognitive disabilities compared to women without disabilities. STUDY DESIGN:We analyzed responses to 12 reproductive health questions added by seven states to their 2013 Behavioral Risk Factor Surveillance System questio...

journal_title：Contraception

authors： Haynes RM,Boulet SL,Fox MH,Carroll DD,Courtney-Long E,Warner L

更新日期：2018-06-01 00:00:00

abstract：:A total of 99 premenopausal and 27 postmenopausal women were evaluated to determine the quantity of glandular proliferation resulting from progestin inhibition of estrogen-primed subjects and of subjects without hormonal stimulation. Endometrial glandular proliferation rates were determined by using mitosis counts, pr...

journal_title：Contraception

authors： Moyer DL,Felix JC

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVES:The present study aims to prospectively evaluate quality of life (QoL) of women using 52-mg levonorgestrel intrauterine system (LNG-IUS) for contraception determined through the Sociedad Española de Contracepción (Spanish contraception Society) (SEC)-QoL, a questionnaire specifically designed to assess the i...

journal_title：Contraception

authors： Cristobal I,Lete LI,Viuda E,Perulero N,Arbat A,Canals I

更新日期：2016-04-01 00:00:00