Abstract:
:Aldophosphamide (NSC 254), a putative key metabolite of cyclophosphamide, has now been isolated as a cyanohydrin derivative from an incubation mixture of cyclophosphamide with mouse liver microsomes in vitro and from the plasma of a cyclophosphamide-treated patient. The cyanohydrin has been shown to be identical with an authenic synthetic sample by mass spectrometry and combined gas chromatography-mass spectrometry.
journal_name
Cancer Resjournal_title
Cancer researchauthors
Fenselau C,Kan MN,Rao SS,Myles A,Friedman OM,Colvin Msubject
Has Abstractpub_date
1977-08-01 00:00:00pages
2538-43issue
8 Pt 1eissn
0008-5472issn
1538-7445journal_volume
37pub_type
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