G-CSF in an infant donor: a method of reducing harvest volume in bone marrow transplantation.

Abstract:

:We report the case of a 4-year-old female with high-risk ALL in first CR who received a BMT from an 11-month-old matched sibling treated with G-CSF in order to obtain an adequate number of mononuclear cells in a limited volume of bone marrow. The absence of toxicity, efficacy of the procedure and quality of the post-transplant clinical outcome suggest such treatments are feasible and useful to overcome problems caused by donor age and/or body weight. In view of this experience we demonstrate how such an approach leads to a notable reduction in risks and in bone marrow donation costs.

journal_name

Bone Marrow Transplant

authors

Pession A,Locatelli F,Prete A,Pigna A,Magrini E,Conte R,Rosito P,Paolucci G

subject

Has Abstract

pub_date

1996-03-01 00:00:00

pages

431-2

issue

3

eissn

0268-3369

issn

1476-5365

journal_volume

17

pub_type

杂志文章
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