Successful medical treatment of two patients with eosinophilic oesophagitis.

Abstract:

BACKGROUND/PURPOSE:Significant oesophageal eosinophilia is associated with oesophagitis and gastroesophageal reflux (GER). Eosinophilic oesophagitis is a rare disease that causes thickening of the oesophageal wall, narrowing of the oesophageal lumen, and severe motor disturbance. METHODS AND RESULTS:Two 12 yr-old patients with eosinophilic oesophagitis were studied prospectively. Clinical and investigation details are presented. Elemental formula was administered until complete remission of disease. Final outcome was assessed after 3 months on regular diet with exclusion of specific allergic components. Both patients responded to the dietary manipulation. CONCLUSIONS:Eosinophilic oesophagitis must be included in the differential diagnosis when dealing with oesophageal strictures of unknown or unclear aetiology. Elimination diet therapy plays a crucial role in ameliorating the course of the illness. Blood eosinophilia correlates with therapeutic response and with improvement of the disease.

journal_name

J Pediatr Surg

authors

De Agustin JC,Sanz N,Canals MJ,Alvarez E,Morales JL,Soler J,Ollero JC,Vazquez J

doi

10.1053/jpsu.2002.30256

subject

Has Abstract

pub_date

2002-02-01 00:00:00

pages

207-13

issue

2

eissn

0022-3468

issn

1531-5037

pii

S0022346802355246

journal_volume

37

pub_type

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