Carbon monoxide-dependent signaling.

abstract：OBJECTIVES:To provide an overview of key elements of the Affordable Care Act. To evaluate ways in which the Affordable Care Act will likely impact the practice of critical care medicine. To describe strategies that may help health systems and providers effectively adapt to changes brought about by the Affordable Care A...

journal_title：Critical care medicine

authors： Dogra AP,Dorman T

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:Review data obtained from high-frequency oscillatory ventilation (HFOV) and mechanical test lung models with respect to delivered tidal volume, distal pressure transmission, endotracheal tube cuff leaks, and simulated clinical conditions. DESIGN:Review of selected studies from PubMed, published abstracts, an...

journal_title：Critical care medicine

authors： Van de Kieft M,Dorsey D,Morison D,Bravo L,Venticinque S,Derdak S

更新日期：2005-03-01 00:00:00

abstract：:During the control period in this study, small premature infants, 1500 g in birth weight, had insensible water loss (IWL) of 2.28 g/kg/hr (equivlaent to 54 ml/kg/day), which is considerably higher than in full term infants. Under phototherapy, there was a significant increase in IWL (3.14 g/kg/hr) associated with incr...

journal_title：Critical care medicine

authors： Yeh TF,Vidyasagar D,Pildes RS

更新日期：1975-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the prevalence and magnitude of weakness in patients receiving chronic mechanical ventilation and the impact of providing aggressive whole-body rehabilitation on conventional weaning variables, muscle strength, and overall functional status. DESIGN:Retrospective analysis of 49 consecutive patient...

journal_title：Critical care medicine

authors： Martin UJ,Hincapie L,Nimchuk M,Gaughan J,Criner GJ

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVES:Venovenous extracorporeal gas exchange is increasingly used in awake, spontaneously breathing patients as a bridge to lung transplantation. Limited data are available on a similar use of extracorporeal gas exchange in patients with acute respiratory distress syndrome. The aim of this study was to investigate...

journal_title：Critical care medicine

authors： Langer T,Vecchi V,Belenkiy SM,Cannon JW,Chung KK,Cancio LC,Gattinoni L,Batchinsky AI

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:Limited data are available on the influence of sedation for critical care therapy with the widely used anesthetic propofol on recovery from acute traumatic brain injury. To establish the influence of propofol on endogenous neurogenesis and functional recovery after traumatic brain injury, rats were sedated wi...

journal_title：Critical care medicine

authors： Thal SC,Timaru-Kast R,Wilde F,Merk P,Johnson F,Frauenknecht K,Sebastiani A,Sommer C,Staib-Lasarzik I,Werner C,Engelhard K

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To assess the coping strategies used by family decision makers of adult critical care patients during and after the critical care experience and the relationship of coping strategies to posttraumatic stress symptoms experienced 60 days after hospitalization. DESIGN:A single-group descriptive longitudinal cor...

journal_title：Critical care medicine

authors： Petrinec AB,Mazanec PM,Burant CJ,Hoffer A,Daly BJ

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVES:To review the immunologic role of the cytokines and the specific role that tumor necrosis factor (TNF) plays in response to infection. The influence of bacterial lipopolysaccharide on TNF, the cytokine cascade, and resultant pathologies are also reviewed. DATA SOURCES:A MEDLINE search of the international E...

journal_title：Critical care medicine

authors： Beutler B,Grau GE

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:To determine whether neutrophil depletion could eradicate intestinal bacterial translocation in bum-injured rats. DESIGN:Prospective, randomized, controlled study. SETTING:University research laboratory. SUBJECTS:Adult male Sprague-Dawley rats. INTERVENTIONS:The rats were intravenously administered a rabb...

journal_title：Critical care medicine

authors： Fazal N,Shamim M,Khan SS,Gamelli RL,Sayeed MM

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVES:In acute respiratory distress syndrome, conservative fluid management increases ventilator-free days without affecting mortality. Response to fluid management may differ based on patients' initial central venous pressure. We hypothesized that initial central venous pressure would modify the effect of fluid m...

journal_title：Critical care medicine

authors： Semler MW,Wheeler AP,Thompson BT,Bernard GR,Wiedemann HP,Rice TW,National Institutes of Health National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Network.

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Insulin reduces morbidity and mortality among critically ill patients, but the molecular mechanisms of its effect remain unknown. Insulin is a well-known inhibitor of glycogen synthase kinase-3, which may play an important role in systemic inflammation and shock. Here we investigate the role of blood glucose ...

journal_title：Critical care medicine

authors： Dugo L,Collin M,Allen DA,Murch O,Foster SJ,Yaqoob MM,Thiemermann C

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:To examine the effect of glycosylated recombinant human tumor necrosis factor binding protein-1 (r-hTNF binding protein-1), the extracellular domain of the tumor necrosis factor receptor p55 produced in mammalian cells, in a rabbit model of circulatory shock due to Escherichia coli. DESIGN:Prospective, rando...

journal_title：Critical care medicine

authors： Porat R,Paddock HN,Schwaitzberg SD,Connolly RJ,Wilkens T,Dasch JR,Gascon MP,Hutchison JS,Ythier A,Wallach D

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVES:To perform a scoping literature review of cognitive, psychiatric, and quality of life outcomes in adults undergoing extracorporeal membrane oxygenation for any indication. DATA SOURCES:We searched PubMed, EMBASE, Cochrane Library, Web of Science, CINAHL, and PsycINFO from inception to June 2019. STUDY SELE...

journal_title：Critical care medicine

authors： Khan IR,Saulle M,Oldham MA,Weber MT,Schifitto G,Lee HB

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To determine the feasibility of utilizing a scintigraphic technique to differentiate patients with adult respiratory distress syndrome due to sepsis syndrome from control volunteers and patients with congestive heart failure. Gamma scintigraphy was compared with chest roentgenograms to predict mortality rate ...

journal_title：Critical care medicine

authors： Byrne K,Tatum JL,Henry DA,Hirsch JI,Crossland M,Barnes T,Thompson JA,Young J,Sugerman HJ

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To report a case of fatal hyperkalemia owing to succinylcholine administration in a patient with mucositis secondary to chemotherapy. DESIGN:Case report. SETTING:Adult intensive care unit (ICU) at Dartmouth-Hitchcock Medical Center. PATIENTS:One patient with mucositis secondary to chemotherapy. MEASUREMEN...

journal_title：Critical care medicine

authors： Al-Khafaji AH,Dewhirst WE,Cornell CJ Jr,Quill TJ

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVES:We examined recommendations within critical care guidelines to describe the pairing patterns for strength of recommendation and quality of evidence. We further identified recommendations where the reported strength of recommendation was strong while the reported quality of evidence was not high/moderate and ...

journal_title：Critical care medicine

authors： Sims CR,Warner MA,Stelfox HT,Hyder JA

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To determine whether partial liquid ventilation (PLV) affects the risk of nosocomial pneumonia. STUDY DESIGN:To assess in vitro bacterial adhesion and viability after liquid perfluorocarbon exposure and to assess bacterial recovery after partial liquid ventilation in vivo in rabbits. SETTING:University anim...

journal_title：Critical care medicine

authors： Sajan I,Scannapieco FA,Fuhrman BP,Steinhorn DM

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:To determine the utility of thoracic computed tomography (TCT) in the initial assessment of critically ill patients with chest injuries. DESIGN:Prospective observational study of cohorts. SETTING:Trauma intensive care unit (ICU) of a Spanish Level III hospital (US equivalent Level I). PATIENTS:Three hundre...

journal_title：Critical care medicine

authors： Guerrero-López F,Vázquez-Mata G,Alcázar-Romero PP,Fernández-Mondéjar E,Aguayo-Hoyos E,Linde-Valverde CM

更新日期：2000-05-01 00:00:00

abstract：:Bed rest is frequently prescribed for critically ill patients because it is assumed to be beneficial for preventing complications, for conserving scarce metabolic resources, and for providing patient comfort. Furthermore, higher levels of physical activity in critically ill patients have been assumed to be impractical...

journal_title：Critical care medicine

authors： Brower RG

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Cortisol clearance is reduced in sepsis and may contribute to the development of impaired adrenocortical function that is thought to contribute to the pathophysiology of critical illness-related corticosteroid insufficiency. We sought to assess adrenocortical function using computer-assisted numerical modelin...

journal_title：Critical care medicine

authors： Dorin RI,Qualls CR,Torpy DJ,Schrader RM,Urban FK 3rd

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:The effect of levosimendan, a novel inotropic vasodilator (inodilator), on the microvascular gastric mucosal hemoglobin oxygenation (muHbo(2)) is unknown. A possible effect could thereby be selective for the splanchnic region or could primarily reflect changes in systemic oxygen transport (Do(2)) and/or oxyge...

journal_title：Critical care medicine

authors： Schwarte LA,Picker O,Bornstein SR,Fournell A,Scheeren TW

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Acute lung injury with subsequent pneumonia and sepsis represents a major cause of morbidity and mortality in thermally injured patients. Production of nitric oxide by the neuronal and inducible nitric oxide synthase may be critically involved in the pathophysiology of the disease process at different time po...

journal_title：Critical care medicine

authors： Lange M,Connelly R,Traber DL,Hamahata A,Cox RA,Nakano Y,Bansal K,Esechie A,von Borzyskowski S,Jonkam C,Traber LD,Hawkins HK,Herndon DN,Enkhbaatar P

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:Case fatality in pregnancy-associated severe sepsis or septic shock appears reduced compared with nonpregnant women with severe sepsis or septic shock. It remains unclear if this difference is due to pregnancy or better baseline health status, among others. Our study compared adverse outcomes of pregnancy-as...

journal_title：Critical care medicine

authors： Kidson KM,Henderson WR,Hutcheon JA

更新日期：2018-11-01 00:00:00

abstract：:Critical Care Medicine encompasses an extremely broad scope. Examination questions were, therefore, chosen to cover a wide variety of critical care topics. A near Gaussian distribution of scores was found for all physician groups studied. We believe the low mean score of 15% reflects the general difficulty of the exam...

journal_title：Critical care medicine

authors： Veremakis C,Taylor RW

更新日期：1983-05-01 00:00:00

abstract：OBJECTIVE:To review the history and development of critical care nurses, the supply and demand issues related to critical care nursing, critical care nursing's contribution to patient outcomes, and recommendations to ensure a steady and strong workforce. DATA SOURCE AND SELECTION:Information presented in this article ...

journal_title：Critical care medicine

authors： Robnett MK

更新日期：2006-03-01 00:00:00

abstract：:We previously reported increased lipid peroxide and decreased alpha-tocopherol levels in the blood of critically ill septic patients. To clarify these results, we investigated lipid peroxidation in experimental septic rats and severely traumatized rats. In septic rats, both platelet count and plasma alpha-tocopherol d...

journal_title：Critical care medicine

authors： Takeda K,Shimada Y,Okada T,Amano M,Sakai T,Yoshiya I

更新日期：1986-08-01 00:00:00

abstract：OBJECTIVES:To create a novel tool to predict favorable neurologic outcomes during ICU stay among children with critical illness. DESIGN:Logistic regression models using adaptive lasso methodology were used to identify independent factors associated with favorable neurologic outcomes. A mixed effects logistic regressio...

journal_title：Critical care medicine

authors： Gupta P,Rettiganti M,Gossett JM,Daufeldt J,Rice TB,Wetzel RC

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Chronic diabetes mellitus (DM) is a known cause of multisystem injury. The effect of DM in acute critical illness may also be detrimental, but is not specifically known. We hypothesized that the preexisting diagnosis of DM is an independent risk factor for mortality in critically ill patients. DESIGN:Paralle...

journal_title：Critical care medicine

authors： Graham BB,Keniston A,Gajic O,Trillo Alvarez CA,Medvedev S,Douglas IS

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that hyperbaric oxygen therapy ameliorates delayed cognitive impairment after acute carbon monoxide poisoning by promoting neurogenesis through upregulating the brain-derived neurotrophic factor in the hippocampus. DESIGN:Laboratory animal experiments. SETTING:University/Medical cente...

journal_title：Critical care medicine

authors： Liu WC,Yang SN,Wu CW,Chen LW,Chan JY

更新日期：2016-01-01 00:00:00

abstract：:The validity of the urinary urea nitrogen (UUN) estimate of total urinary nitrogen (TUN) was tested in patients who required iv nutrition. UUN and TUN were determined in 120 urine collections from ten preoperative, 13 postoperative, and 11 stressed patients. The relationship between TUN and UUN was examined by linear ...

journal_title：Critical care medicine

authors： Loder PB,Kee AJ,Horsburgh R,Jones M,Smith RC

更新日期：1989-04-01 00:00:00