Extending the reading time increases the accuracy of rapid whole blood test for diagnosis of Helicobacter pylori infection.

Abstract:

BACKGROUND:To evaluate the accuracy of two rapid whole blood tests (the BM-Test Helicobacter pylori and the QuikPac IV One Step H. pylori Whole Blood Test), and compare this to a conventional quantitative ELISA test (HEL-p TEST II). METHODS:Helicobacter pylori status in dyspeptic patients was assessed by culture, histology, and rapid urease tests on biopsies from the antrum and corpus. The optimal cut-off value of the reading time for the rapid blood tests was determined by using the receiver characteristics operative (ROC) curves. RESULTS:In the 141 patients examined, 89 were infected, 51 were not infected, and one was indeterminate (only positive in either urease test or histology). Areas under ROC curves were greater in the BM-Test compared with the QuikPac IV (0.948 vs 0.840, P < 0.01), with their most appropriate cut-off reading times at 360 and 395 min, respectively, rather than 10 min as suggested by the manufacturer. The sensitivity and specificity were 94.4% and 94.1% at 360 min, and 74.2 and 96.1% at 10 min for the BM-Test; 80.9, 76.5 at 395 min and 3.4 and 100% at 10 min for the QuikPac IV. The antibody titer of the quantitative ELISA test was negatively correlated with the reaction time of the two rapid blood tests in H. pylori-infected patients (P < 0.05, r=-0.3). CONCLUSIONS:The BM-Test is an appropriate office-based test for diagnosing H. pylori infection in Chinese patients. Extending the reading time would facilitate the readability of rapid blood tests with a resultant increase in accuracy.

authors

Chen TS,Chang FY,Lee SD

doi

10.1046/j.1440-1746.2001.02630.x

subject

Has Abstract

pub_date

2001-12-01 00:00:00

pages

1341-5

issue

12

eissn

0815-9319

issn

1440-1746

pii

2630

journal_volume

16

pub_type

杂志文章
  • Epidemiology of Helicobacter pylori and peptic ulcer in India.

    abstract:BACKGROUND:There is a wide variation in the prevalence of peptic ulcer in India both before and since the use of endoscopy. We studied the prevalence of peptic ulcer disease in a community in northern India and its relationship with Helicobacter pylori infection. METHODS:A house-to-house survey of residents aged 15 ye...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2002.02746.x

    authors: Singh V,Trikha B,Nain CK,Singh K,Vaiphei K

    更新日期:2002-06-01 00:00:00

  • Discrepant effects of inducible nitric oxide synthase modulation on systemic and splanchnic endothelial nitric oxide synthase activity and expression in cirrhotic rats.

    abstract:BACKGROUND:Arterial vasodilatation, which is a major factor in the pathogenesis of the hyperkinetic circulatory state and portal hypertension in cirrhosis, is due to arterial nitric oxide (NO) overproduction secondary to endothelial NO synthase (eNOS) and inducible NOS (iNOS) upregulation. However, in cirrhosis, the re...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2006.04608.x

    authors: Malyshev E,Tazi KA,Moreau R,Lebrec D

    更新日期:2007-12-01 00:00:00

  • Hepatic steatosis in chronic hepatitis C virus infection: prevalence and clinical correlation.

    abstract:BACKGROUND AND AIMS:Hepatic steatosis is a histological characteristic in patients with chronic hepatitis C virus (HCV) infection. The aim of this study was to evaluate the prevalence of hepatic steatosis in Chinese patients with chronic hepatitis C, and to look for possible correlation with various histopathological c...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2001.02407.x

    authors: Hwang SJ,Luo JC,Chu CW,Lai CR,Lu CL,Tsay SH,Wu JC,Chang FY,Lee SD

    更新日期:2001-02-01 00:00:00

  • Fecal calprotectin and need of multiple microbiota trasplantation infusions in Clostridium difficile infection.

    abstract:BACKGROUND AND AIM:Fecal microbiota transplantation (FMT) has proven to be very effective in recurrent Clostridium difficile infection (CDI) when compared with standard antibiotic therapy. However, given the lack of validated criteria, decision regarding number and timing of infusions is currently based on the clinicia...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.15072

    authors: Gallo A,Cancelli C,Ceron E,Covino M,Capoluongo E,Pocino K,Ianiro G,Cammarota G,Gasbarrini A,Montalto M

    更新日期:2020-11-01 00:00:00

  • The significance of glypican-3 expression profiling in the tumor cellular origin theoretical system for hepatocellular carcinoma progression.

    abstract:BACKGROUND AND AIM:Glypican-3 (GPC3) expression is correlated with poor prognosis and progression in hepatocellular carcinoma (HCC). HCC progression can be associated with the differentiation status of tumor cell before malignant transformation. Our aim was to investigate the dynamic expression of GPC3 during tumor cel...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.13736

    authors: Xue R,Feng J,Meng Q,Lv F,Zhu Y,Yu H,Zhang S,Song C,Sun L,Yue Z,Feng S,Che R,Xiang Q,Jing X

    更新日期:2017-08-01 00:00:00

  • High incidence of zinc deficiency among Filipino children with compensated and decompensated liver disease.

    abstract:BACKGROUND AND AIM:The role of zinc in the nutrition and growth of children with chronic liver disease is poorly defined. The present study determined the serum zinc levels of children with compensated liver disease (CLD) and decompensated liver disease (DLD) and compared this with healthy children. Zinc levels were al...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2009.06003.x

    authors: Umusig-Quitain P,Gregorio GV

    更新日期:2010-02-01 00:00:00

  • Structural and functional analysis of full-length hepatitis B virus genomes in patients: implications in pathogenesis.

    abstract::The structural analysis, replicative efficiency and immunogenicity of hepatitis B virus (HBV) full-length genomes isolated from different patients or asymptomatic carriers are presented in the present review. Data indicate the importance of viral genome-based studies in elucidating the pathogenesis of HBV infections. ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1440-1746.2003.03158.x

    authors: Wen YM

    更新日期:2004-05-01 00:00:00

  • Endoscopic management of postoperative bile leak.

    abstract::Significant bile leak is an uncommon but serious complication of biliary tract surgery. Of twenty-five patients presenting with postoperative bile leak, 11 had complete tie-off of common bile duct and required surgery, while the remaining 14 had injury without complete obstruction and could be managed by endoscopic me...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1996.tb00052.x

    authors: Saraswat VA,Choudhuri G,Sharma BC,Agarwal DK,Gupta R,Baijal SS,Sikora SS,Saxena R,Kapoor VK

    更新日期:1996-02-01 00:00:00

  • Association between chronic hepatitis B virus infection and interleukin-10, tumor necrosis factor-alpha gene promoter polymorphisms.

    abstract:BACKGROUND:The reasons for the viral persistence of hepatitis B virus infection (HBV) are unknown, but are probably related to host immune factors. Cytokines play a significant role in immune defense. The present study was undertaken to investigate the association between HBV infection and polymorphisms of tumor necros...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2006.04304.x

    authors: Cheong JY,Cho SW,Hwang IL,Yoon SK,Lee JH,Park CS,Lee JE,Hahm KB,Kim JH

    更新日期:2006-07-01 00:00:00

  • Case report: hepatic adenoma with bone marrow metaplasia in a patient with glycogen storage disease type 1a.

    abstract::A 34 year old man with glycogen storage disease type 1a had two hepatic tumours since 18 years of age. They had continued to grow until he was 24 years old, but showed no further growth since then. He underwent a right hepatic trisegmentectomy with caudate lobectomy under veno-venous bypass. The tumour in the posterio...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1996.tb01702.x

    authors: Moriura S,Kuroda M,Kimura A,Iwatsuka Y,Ikeda S,Sakai T,Usui A

    更新日期:1996-06-01 00:00:00

  • Correlation of Barrett's esophagus with colorectal polyps in Japanese patients: A retrospective chart review.

    abstract:BACKGROUND AND AIM:Barrett's esophagus and colorectal polyps have several overlapping risk factors. Whereas several reports in Western countries have indicated a close relationship between Barrett's esophagus and colorectal polyps, the relationship between these two diseases remains unclear in Japan. This study was per...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.14610

    authors: Takedomi H,Tsuruoka N,Takamori A,Miyahara K,Yamanouchi K,Shimamura T,Fujimoto Y,Noda T,Matsunaga T,Takara Y,Shimada F,Hidaka H,Endo H,Anzai K,Fujimoto K

    更新日期:2019-07-01 00:00:00

  • Management of patients with chronic hepatitis B.

    abstract::Better understanding of hepatitis B virus (HBV) replication and the natural history and immunopathogenesis of chronic hepatitis B, together with the introduction of effective agents with different mechanisms of action, is the basis for better therapeutic strategies against chronic hepatitis B. Substantial experience h...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1046/j.1440-1746.2002.02736.x

    authors: Liaw YF

    更新日期:2002-04-01 00:00:00

  • Autoimmune hepatitis: East meets west.

    abstract::Autoimmune hepatitis (AIH) is an inflammatory liver disease with diverse clinical spectrum, which predominantly affects females. This review provides detailed comparisons of epidemiology, genetic predispositions, clinical features, risk factors of hepatocellular carcinoma, and mortality in AIH patients between eastern...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1111/jgh.12952

    authors: Yang F,Wang Q,Bian Z,Ren LL,Jia J,Ma X

    更新日期:2015-08-01 00:00:00

  • Expression and immunogenicity of NY-ESO-1 in hepatocellular carcinoma.

    abstract:BACKGROUND AND AIM:The present study was designed to investigate the expression of and humoral response against NY-ESO-1 in patients with hepatocellular carcinoma and to analyze the relationship between expression of NY-ESO-1 mRNA and clinicopathological features. METHODS:NY-ESO-1 mRNA and protein expression in surgic...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2006.04271.x

    authors: Nakamura S,Nouso K,Noguchi Y,Higashi T,Ono T,Jungbluth A,Chen YT,Old LJ,Nakayama E,Shiratori Y

    更新日期:2006-08-01 00:00:00

  • Duplex Doppler ultrasound of the ligamentum teres and portal vein: a clinically useful adjunct in the evaluation of patients with known or suspected chronic liver disease or portal hypertension.

    abstract::The prevalence and potential value of the detection of signs of portal hypertension by duplex Doppler ultrasound (DDU) of the ligamentum teres and portal vein in patients with known or suspected chronic liver disease and/or portal hypertension was studied in 136 consecutive patients undergoing clinical assessment incl...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1991.tb01147.x

    authors: Gibson PR,Gibson RN,Donlan JD,Ditchfield MR,Bhathal PS

    更新日期:1991-01-01 00:00:00

  • Intra-arterial carbon dioxide-enhanced ultrasonogram of hepatocellular carcinoma treated by transcatheter arterial embolization and percutaneous ethanol injection therapy.

    abstract::The purpose of this study was to investigate the value of carbon dioxide-enhanced ultrasonography (CO2-US) in the evaluation of viable hepatocellular carcinomas (HCC) which were treated by transcatheter arterial embolization (TAE), percutaneous ethanol injection (PEI), or a combination treatment (TAE and PEI). Forty-o...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1998.tb00543.x

    authors: Chen RC,Wang CK,Chiang LC,Lo HY,Duh SJ,Chen WT,Tu HY,Liao LY,Wang CS,Chen PH

    更新日期:1998-01-01 00:00:00

  • Clinical significance of hiatal hernia in the development of gastroesophageal reflux after distal gastrectomy for cancer of the stomach.

    abstract:BACKGROUND AND AIMS:The relationship between gastroesophageal reflux disease and sliding hernia is controversial, especially following distal partial gastrectomy in patients with gastric cancer. The aim of this study was to examine the relationship between gastroesophageal reflux disease and sliding hernia of the esoph...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2006.04135.x

    authors: Fujiwara Y,Nakao K,Inoue T,Koishi K,Nishio Y,Yagyu R,Nakagawa K,Yamamura T

    更新日期:2006-07-01 00:00:00

  • Distal colonic neoplasms predict proximal neoplasia in average-risk, asymptomatic subjects.

    abstract::Flexible sigmoidoscopy has been recommended as a screening method to reduce the incidence of colorectal cancer in asymptomatic, average-risk subjects through the early detection and removal of polyps. However, the association between distal and proximal colonic neoplasia and, hence, the requirement for colonoscopic fo...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.1999.01804.x

    authors: Collett JA,Platell C,Fletcher DR,Aquilia S,Olynyk JK

    更新日期:1999-01-01 00:00:00

  • Role of the longitudinal smooth muscle coat in the ileal motile activity: evidence of ileo-ileal inhibitory reflex.

    abstract:BACKGROUND:All gut movements are claimed to be activated essentially by the concentric contraction of the circular muscle, moving the chyme aborally. The role of the longitudinal smooth muscle of the small intestine in gut motility is poorly understood; this point was investigated in the current study. METHODS:The abd...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2002.02870.x

    authors: Shafik A,Shafik AA,Ahmed I

    更新日期:2002-12-01 00:00:00

  • Gallbladder cancer: can newer insights improve the outcome?

    abstract::Gallbladder cancer (GBC) is the leading cause of cancer related mortality in certain geographic areas. Most of the patients with GBC have advanced disease at presentation, precluding curative resection resulting in a dismal prognosis. However, recent advances in the understanding of its epidemiology and pathogenesis c...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1440-1746.2011.07048.x

    authors: Dutta U

    更新日期:2012-04-01 00:00:00

  • The association between non-alcoholic fatty liver disease (with or without metabolic syndrome) and extrahepatic cancer development.

    abstract:BACKGROUND AND AIM:This study was designed to determine whether non-alcoholic fatty liver disease (NAFLD), with or without metabolic syndrome (MetS), is a risk factor for cancer development. METHODS:We conducted a retrospective longitudinal study at the Center for Preventive Medicine, St. Luke's International Hospital...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.15350

    authors: Yamamoto K,Ikeya T,Okuyama S,Fukuda K,Kobayashi D

    更新日期:2020-11-17 00:00:00

  • Interactions of cytokines, S-Adenosylmethionine, and S-Adenosylhomocysteine in alcohol-induced liver disease and immune suppression.

    abstract::Alcoholic liver disease (ALD) remains a leading cause of death in the USA. Defining mechanisms for liver cell death in ALD in order to develop potential new agents for therapeutic intervention is a major focus of the authors' work. Abnormal cytokine metabolism is a major feature of ALD, and a thorough understanding of...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1440-1746.2006.04590.x

    authors: Barve S,Joshi-Barve S,Song Z,Hill D,Hote P,Deaciuc I,McClain C

    更新日期:2006-10-01 00:00:00

  • Role of enhanced multi-detector-row computed tomography before urgent endoscopy in acute upper gastrointestinal bleeding.

    abstract:BACKGROUND AND AIM:Multi-detector-row computed tomography (MDCT) has been reported to be a potentially useful modality for detection of the bleeding origin in patients with acute upper massive gastrointestinal (GI) bleeding. The purpose of this study is to investigate the efficacy of MDCT as a routine method for detect...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.12447

    authors: Miyaoka Y,Amano Y,Ueno S,Izumi D,Mikami H,Yazaki T,Okimoto E,Sonoyama T,Ito S,Fujishiro H,Kohge N,Imaoka T

    更新日期:2014-04-01 00:00:00

  • Interobserver agreement in contrast harmonic endoscopic ultrasound.

    abstract:BACKGROUND AND AIM:Contrast harmonic endoscopic ultrasound (CH-EUS) was recently introduced to clinical practice; its reproducibility among endosonographers is unknown. Our aim was to assess the interobserver agreement (IA) in CH-EUS. METHODS:Fifteen endosonographers (eight experienced and seven non-experienced) from ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1440-1746.2012.07115.x

    authors: Fusaroli P,Kypraios D,Mancino MG,Spada A,Benini MC,Bianchi M,Bocus P,De Angelis C,De Luca L,Fabbri C,Grillo A,Marzioni M,Reggio D,Togliani T,Zanarini S,Caletti G

    更新日期:2012-06-01 00:00:00

  • Prospective evaluation of a clinical guideline recommending early patients discharge in bleeding peptic ulcer.

    abstract:BACKGROUND AND AIM:To validate an early discharge policy in patients admitted with upper gastrointestinal bleeding (UGIB) due to ulcers. METHODS:Patients with gastroduodenal ulcer or erosive gastritis/duodenitis were included in a previous study aiming to develop a practice guideline for early discharge of patients wi...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2010.06374.x

    authors: Chaparro M,Barbero A,Martín L,Esteban C,Espinosa L,de la Morena F,Sánchez A,Martín I,Santander C,Moreno-Otero R,Gisbert JP

    更新日期:2010-09-01 00:00:00

  • Helicobacter pylori cagA, iceA and vacA status in Taiwanese patients with peptic ulcer and gastritis.

    abstract:BACKGROUND:Helicobacter pylori causes chronic gastritis, peptic ulcer, gastric cancer and mucosa-associated lymphoid tissue (MALT) lymphoma. Different genotypes of H. pylori are confirmed from diverse geographical areas. Its association with clinical diseases remains controversial. The aim of the present study was to i...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2003.03214.x

    authors: Perng CL,Lin HJ,Sun IC,Tseng GY,Facg

    更新日期:2003-11-01 00:00:00

  • Fetal and infant exposure to the Chinese famine increases the risk of fatty liver disease in Chongqing, China.

    abstract:BACKGROUND AND AIM:Early life exposure to the famine may affect the susceptibility to the metabolic disorders. The objective of this study was to examine the associations of early life exposure to the Chinese Famine (1959-1961) with the risk of fatty liver disease, obesity, hypertension, and hyperglycemia in adulthood....

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.13044

    authors: Chen JP,Peng B,Tang L,Sun R,Hu S,Wen XY,Que P,Wang YH

    更新日期:2016-01-01 00:00:00

  • The efficacy of oral Zhizhu Kuanzhong, a traditional Chinese medicine, in patients with postprandial distress syndrome.

    abstract:BACKGROUND AND AIM:The treatment of patients with functional dyspepsia (FD) remains unsatisfactory. We assessed the efficacy of Zhizhu Kuanzhong (ZZKZ) capsule, a traditional Chinese medicine formula, in patients with postprandial distress syndrome (PDS) of FD. METHODS:The study was designed as a multicenter, randomiz...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1111/jgh.14467

    authors: Xiao Y,Li Y,Shu J,Li Y,Xu J,Ren J,Liu D,Wang J,Zhou L,Li Y,Tang G,Tian D,Zhang S,Hou X,Wang H,Li Z,Lv N,Chen M

    更新日期:2019-03-01 00:00:00

  • Safety and efficacy of antibiotic prophylaxis in patients undergoing elective laparoscopic cholecystectomy: A systematic review and meta-analysis.

    abstract:BACKGROUND AND AIM:Owing to persistent controversy regarding the use of routine antibiotic prophylaxis in patients undergoing elective laparoscopic cholecystectomy and the availability of several new randomized controlled trials (RCTs), we conducted an up-to-date meta-analysis to provide the best current evidence. The ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/jgh.13246

    authors: Liang B,Dai M,Zou Z

    更新日期:2016-05-01 00:00:00

  • Experimental investigation of the role of endothelin-1 in idiopathic portal hypertension.

    abstract:BACKGROUND AND AIM:The authors' previous report revealed that endothelin-1 might be released from B lymphocytes in cirrhotic patients with hypersplenism. Other investigators have shown that persistent exposure to environmental contaminants including arsenic might induce idiopathic portal hypertension. The aim of this s...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2006.04822.x

    authors: Yamaguchi E,Yamanoi A,Ono T,Nagasue N

    更新日期:2007-07-01 00:00:00