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"Subclinical" orthostatic hypotension is associated with dizziness in elderly patients with Parkinson disease.

Abstract：

OBJECTIVE:To investigate risk factors associated with subjective complaints of dizziness in 12 elderly patients with Parkinson disease (PD), in whom no obvious cause for this symptom could be found. DESIGN:A case-controlled study, with patients prospectively recruited in a nonblinded fashion. SETTING:Patients were seen by one physician at a neurology outpatient clinic between August 1993 and August 1994. SUBJECTS:Thirty-six patients, all over age 65 years and all with PD; 12 complained of dizziness; 24 did not. INTERVENTIONS:Patients and controls were screened for blood pressure changes, postural instability, motor severity, multiple sensory deficits, drug use, cardiovascular disease, and diabetes mellitus. MAIN OUTCOME MEASURES:An orthostatic decrease of systolic BP > 15 mmHg (odds ratio = 6.5; 95% confidence interval = 1.22 - 34.52; chi 2mh = 6.7; p < .01) and an orthostatic decrease of diastolic BP > 5mmHg (odds ratio = 11; 95% confidence interval = 3.15 - 38.39; chi 2mh = 7.14; p < .01) were significant risk factors for complaints of dizziness. RESULTS:The only significant risk factors linked with dizziness were orthostatic decreases in systolic (15 mmHg) and diastolic (5 mmHg) blood pressure. CONCLUSIONS:An orthostatic decrease in blood pressure is associated with unexplained feelings of dizziness in elderly PD patients.

journal_name

Arch Phys Med Rehabil

journal_title

Archives of physical medicine and rehabilitation

authors

Hillen ME,Wagner ML,Sage JI

doi

10.1016/s0003-9993(96)90013-1

subject

Has Abstract

pub_date

1996-07-01 00:00:00

pages

710-2

issue

7

eissn

0003-9993

issn

1532-821X

pii

S0003-9993(96)90013-1

journal_volume

77

pub_type

杂志文章

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