Fas (Apo-1/CD95) and Fas ligand interaction between gastric cancer cells and immune cells.

abstract：BACKGROUND AND AIM:The PyloriTek Test Kit (a 1-h rapid urease test) was developed for the rapid diagnosis of Helicobacter pylori (H. pylori) during endoscopy. Most studies were performed in Western populations. The aim of this study was to evaluate the PyloriTek test for the diagnosis of H. pylori infection in Chinese ...

journal_title：Journal of gastroenterology and hepatology

authors： Wong WM,Wong BC,Tang VS,Lai KC,Yuen ST,Leung SY,Hu WH,Lam SK

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND AND AIM:CDKN2A/CDKN2B locus on 9p21 is reported to be associated with various diseases, including cancer and cardiovascular and inflammatory diseases. Significant downregulation of CDKN2B-AS1 in inflamed colon tissue of inflammatory bowel disease (IBD) cases was reported in Europeans. This study aimed to con...

journal_title：Journal of gastroenterology and hepatology

authors： Lee HS,Lee SB,Kim BM,Hong M,Jung S,Hong J,Baek J,Han B,Oh SH,Kim KM,Park SH,Yang SK,Ye BD,Song K

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Regional variations in inflammatory bowel disease (IBD) rates have been observed. Limited epidemiological data are available from Australasia. IBD prevalence rates have never been assessed in an Australian population-based setting. In addition, there are few historical IBD incidence data to allow as...

journal_title：Journal of gastroenterology and hepatology

authors： Studd C,Cameron G,Beswick L,Knight R,Hair C,McNeil J,Desmond P,Wilson J,Connell W,Bell S

更新日期：2016-01-01 00:00:00

abstract：:Wilson's disease is an autosomal recessive, inborn error of copper metabolism. The basic defect is unknown but decreased biliary excretion of copper is associated with copper accumulation and damage to the liver, brain and other organs with variable clinical expression. The gene for the disease has been mapped to band...

journal_title：Journal of gastroenterology and hepatology

authors： Frydman M

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND AND AIM:The activation of Rho proteins has been shown to lead to loss of polarity in cancer cells, as well as reorganization of the cytoskeleton and facilitation of cell motility, possibly resulting in their malignant potential. The clinicopathological significance of RhoA, however, is not yet well known in ...

journal_title：Journal of gastroenterology and hepatology

authors： Wang D,Dou K,Xiang H,Song Z,Zhao Q,Chen Y,Li Y

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND AND AIM:Fusobacterium nucleatum (Fn) is involved in colorectal cancer (CRC) growth and is a biomarker for patient prognosis and management. However, the ecology of Fn in CRC and the distribution of intratumoral Fn are unknown. METHODS:We evaluated Fn and the status of KRAS and BRAF in 200 colorectal neoplas...

journal_title：Journal of gastroenterology and hepatology

authors： Yamamoto S,Kinugasa H,Hirai M,Terasawa H,Yasutomi E,Oka S,Ohmori M,Yamasaki Y,Inokuchi T,Harada K,Hiraoka S,Nouso K,Tanaka T,Teraishi F,Fujiwara T,Okada H

更新日期：2020-11-26 00:00:00

abstract：:The relationship between the intragastric pH measured by 24 h pH monitoring system and the serum pepsinogen I/II ratio was studied in 68 cases. When pepsinogen I/II ratio was compared with pH 3.0 holding time (the percentage time during which the gastric pH is above 3.0), there was a negative correlation between these...

journal_title：Journal of gastroenterology and hepatology

authors： Kinoshita Y,Yamashita Y,Kitajima N,Tojo M,Itoh T,Fukuzaki H,Chiba T

更新日期：1995-03-01 00:00:00

abstract：:The incidence of obesity is increasing in Asia, with implications on gastrointestinal (GI) and liver diseases. The Gut and Obesity in Asia Workgroup comprises regional experts with the aim of studying relationship between obesity and the GI and liver diseases in Asia. Through literature review and the modified Delphi ...

journal_title：Journal of gastroenterology and hepatology

authors： Koh JC,Loo WM,Goh KL,Sugano K,Chan WK,Chiu WY,Choi MG,Gonlachanvit S,Lee WJ,Lee WJ,Lee YY,Lesmana LA,Li YM,Liu CJ,Matsuura B,Nakajima A,Ng EK,Sollano JD,Wong SK,Wong VW,Yang Y,Ho KY,Dan YY

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The CLOtest and other rapid urease detection kits are widely used in the endoscopic diagnosis of Helicobacter pylori. A new formulation CLOtest has been developed with the goal of obtaining a positive result more rapidly. The aims of this study were to validate the sensitivity and specificity of the...

journal_title：Journal of gastroenterology and hepatology

authors： Viiala CH,Windsor HM,Forbes GM,Chairman SO,Marshall BJ,Mollison LC

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND AIM:We previously discovered that tumor suppressor candidate 3 (TUSC3) was overexpressed and predicted worse prognosis in colon cancer patients. However, the mechanisms of upregulation of TUSC3 in colon cancer remained unclear. METHODS:MiR-873-5p was predicted and identified as the regulator of TUSC3 vi...

journal_title：Journal of gastroenterology and hepatology

authors： Zhu Y,Zhang X,Qi M,Zhang Y,Ding F

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Intestinal endotoxin (lipopolysaccharide) is thought to contribute to liver injury in both alcoholic and nonalcoholic steatohepatitis (NASH). Tumor necrosis factor alpha (TNFalpha) is an important mediator of this process and is considered central to the inflammatory response in NASH. This study aim...

journal_title：Journal of gastroenterology and hepatology

authors： Kirsch R,Clarkson V,Verdonk RC,Marais AD,Shephard EG,Ryffel B,de la M Hall P

更新日期：2006-01-01 00:00:00

abstract：:Viral hepatitis is defined as a hepatitis virus infection in which hepatic inflammation and necrosis lead to a characteristic feature. It is caused by at least five viral agents with specific epidemiological attributes and distinctive immunoserologic findings. The well-characterized forms are hepatitis A, B, C, D and ...

journal_title：Journal of gastroenterology and hepatology

authors： Nishioka M,Morshed SA

更新日期：1997-06-01 00:00:00

abstract：AIM:To investigate the morphological changes of intratumoral microvessels after administration of thalidomide in occult hepatic metastases. METHODS:Twenty mice with hepatic metastases created by injection of colon-26 tumor cells into the spleen were enrolled. Ten mice were treated with thalidomide (200 mg/kg) by intra...

journal_title：Journal of gastroenterology and hepatology

authors： Liu Y,Li H,Matsui O

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:: Previously, we have observed that highly unsaturated dietary (n-3) fatty acids inhibit cell proliferation in conjunction with stimulation of insulin-like growth factor-binding protein (IGFBP)-6 secretion in Caco-2 cells, a human colon carcinoma cell line. METHODS:: To test the converse hypothesis that inh...

journal_title：Journal of gastroenterology and hepatology

authors： Kim EJ,Schaffer BS,Kang YH,Macdonald RG,Park JH

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND AND AIM:The oral manifestations of familial adenomatous polyposis (FAP) have been reported in the recent literature. Therefore, there has been growing interest in the characterization of the dento-osseous anomalies because they may precede colorectal cancer and may be used as a diagnostic marker. This system...

journal_title：Journal of gastroenterology and hepatology

authors： Almeida FT,Pachêco-Pereira C,Porporatti AL,Flores-Mir C,Leite AF,De Luca Canto G,Guerra EN

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND AIM:To guide selection of optimal screening strategies for advanced colorectal neoplasia (ACRN), we evaluated the screening performances of sigmoidoscopy, fecal immunochemical test (FIT), and the Asia-Pacific Colorectal Screening (APCS) system, as well as combinations of these techniques. METHODS:We rev...

journal_title：Journal of gastroenterology and hepatology

authors： Jung YS,Park CH,Kim NH,Park JH,Park DI,Sohn CI

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND AND AIM:Differentially expressed (DE) genes detected at the population-level through case-control comparison provide no information on the dysregulation frequencies of DE genes in a cancer. In this work, we aimed to identify the genes with universally upregulated or downregulated expressions in colorectal ca...

journal_title：Journal of gastroenterology and hepatology

authors： Song K,Su W,Liu Y,Zhang J,Liang Q,Li N,Guan Q,He J,Bai X,Zhao W,Guo Z

更新日期：2019-05-01 00:00:00

abstract：:Primary liver cancer, particularly hepatocellular carcinoma (HCC) remains a significant disease worldwide. It is among the top three causes of cancer death in the Asia Pacific region because of the high prevalence of its main etiological agents, chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. I...

journal_title：Journal of gastroenterology and hepatology

authors： Yuen MF,Hou JL,Chutaputti A,Asia Pacific Working Party on Prevention of Hepatocellular Carcinoma.

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND AIM:Interferon and ribavirin combination therapy for chronic hepatitis C produces hemolytic anemia. This study was conducted to identify the factors contributing to ribavirin-induced anemia. METHODS:Eighty-eight patients with chronic hepatitis C who received interferon-alpha-2b at a dose of 6 MU adminis...

journal_title：Journal of gastroenterology and hepatology

authors： Nomura H,Tanimoto H,Kajiwara E,Shimono J,Maruyama T,Yamashita N,Nagano M,Higashi M,Mukai T,Matsui Y,Hayashi J,Kashiwagi S,Ishibashi H

更新日期：2004-11-01 00:00:00

abstract：:Capsules (8 x 30 mm) of technetium-99m pertechnetate were designed for measurement of portal blood flow. Most of the radionuclide entered the superior mesenteric vein. The capsule was taken orally and monitored with a collimator for scintigraphy until it reached the small intestine, when a magnetic field completed an ...

journal_title：Journal of gastroenterology and hepatology

authors： Shiomi S,Kuroki T,Ueda T,Nishiguchi S,Nakajima S,Kobayashi K,Kurai O,Ikeoka N,Monna T,Ochi H

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:The relationship between Helicobacter pylori eradication and gastric emptying has been reported; however, the effect of eradication therapy on gastric emptying is still unclear. This study evaluated the relationship between three gastric emptying techniques, the scintigraphic technique, the 13C-octanoic acid...

journal_title：Journal of gastroenterology and hepatology

authors： Kachi M,Shirasaka D,Aoyama N,Ebara S,Miki I,Morita Y,Tamura T,Kasuga M

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND AIM:Multidrug resistance associated gene product 2 (Mdr2) is believed to have a significant role in biliary cholesterol and phospholipid secretions. Both pravastatin and bezafibrate resulted in Mdr2 induction, but increased cholesterol secretion was observed only in pravastatin treatment. To explore the ...

journal_title：Journal of gastroenterology and hepatology

authors： Kamisako T,Ogawa H

更新日期：2004-08-01 00:00:00

abstract：:Mucus and bicarbonate secretions have been widely implicated as an important pre-epithelial protective barrier against autodigestion of the gastric mucosa by acid and pepsin. Evidence from several independent studies shows there is a continuous layer of resilient viscoelastic mucus gel adherent to the surface of the g...

journal_title：Journal of gastroenterology and hepatology

authors： Copeman M,Matuz J,Leonard AJ,Pearson JP,Dettmar PW,Allen A

更新日期：1994-01-01 00:00:00

abstract：:We evaluated the clinical usefulness of a protein induced by vitamin K absence, antagonist-prothrombin (PIVKA-II), in detecting hepatocellular carcinoma (HCC) specifically in patients with liver cirrhosis, and the possible correlation between levels of PIVKA-II and pathological features of HCC. Plasma levels of PIVKA-...

journal_title：Journal of gastroenterology and hepatology

authors： Takikawa Y,Suzuki K,Yamazaki K,Goto T,Madarame T,Miura Y,Yoshida T,Kashiwabara T,Sato S

更新日期：1992-01-01 00:00:00

abstract：:There are approximately 277,000 new cases of pancreatic cancer and 266,000 deaths from pancreatic cancer annually, indicating a mortality rate of 96% of the cases diagnosed. Because of the ineffectiveness of therapies, a major emphasis needs to be placed on prevention. This paper reviews the epidemiology and risk fact...

journal_title：Journal of gastroenterology and hepatology

authors： Pandol S,Gukovskaya A,Edderkaoui M,Dawson D,Eibl G,Lugea A

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND AIM:6-Mercaptopurine (6-MP) and azathioprine (AZA) are widely used as maintenance therapy in children with inflammatory bowel disease (IBD). However, proper 6-thioguanine nucleotide (6-TGN) concentrations in Japanese children with IBD have not been reported. METHODS:This retrospective review examines 32...

journal_title：Journal of gastroenterology and hepatology

authors： Ohtsuka Y,Arai K,Aoyagi Y,Fujii T,Yamakawa Y,Ohtani K,Ikuse T,Baba Y,Inage E,Kudo T,Suzuki R,Nagata S,Shimizu T

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The present study examined the effects of NS-398, a specific cyclo-oxygenase-2 inhibitor, on gastric mucosal cell kinetics and gastric wound healing following acid-induced injury. METHODS:Male Sprague-Dawley rats were fasted for 24 h and then 0.6 mol/L hydrochloric acid (HCl; 1 mL) was administered...

journal_title：Journal of gastroenterology and hepatology

authors： Sun WH,Tsuji S,Tsujii M,Gunawan ES,Sawaoka H,Kawai N,Iijima H,Kimura A,Kakiuchi Y,Yasumaru M,Sasaki Y,Kawano S,Hori M

更新日期：2000-07-01 00:00:00

abstract：:Both celiac disease and non-cirrhotic portal fibrosis are known to be associated with various autoimmune diseases and have numerous immunological abnormalities. Herein two patients with celiac disease having associated non-cirrhotic portal fibrosis are reported. An autoimmune link between the two conditions is likely ...

journal_title：Journal of gastroenterology and hepatology

authors： Sharma BC,Bhasin DK,Nada R

更新日期：2006-01-01 00:00:00

abstract：:The results of hepatectomy, percutaneous ethanol injection therapy and transcatheter arterial embolization for small hepatocellular carcinoma (HCC) of 3 cm or less in diameter from the published literature were compared with the authors' experiences with surgical treatment. The survival rates for those treated by hepa...

journal_title：Journal of gastroenterology and hepatology

authors： Yamasaki S,Hasegawa H,Makuuchi M,Takayama T,Kosuge T,Shimada K

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Hypothyroidism is commonly thought to cause decreased gastric emptying but is mostly associated with autoimmune disease. In the present study the gastric emptying function of thyroid cancer patients with severe hypothyroidism of short duration was evaluated with a radionuclide solid meal gastric emptying stu...

journal_title：Journal of gastroenterology and hepatology

authors： Kao PF,Lin JD,Chiu CT,Hsu HT,See LC,Tzen KY

更新日期：2004-06-01 00:00:00