Abstract:
:Regions of DNA homology between human and marmoset (Callithrix jacchus) chromosomes have been demonstrated using fluorescence in situ hybridization. All 24 chromosome paints and two centromere repeat sequences from Homo sapiens (HSA) have been annealed to previously G-banded metaphase spreads of Callithrix jacchus. All human paint probes, except Y, successfully hybridized to marmoset chromosomes. Fifteen of them hybridized to one region only, seven to two regions, and paint 1 to three regions. Homologies proposed from previous banding comparisons have been confirmed for HSA 2, 4-6, 10-12, 18, 19, 21 and X and partially confirmed for HSA 1 and 3, but were not in agreement for HSA 14 and 17. Human centromere repeat sequences for X and 18 did not hybridize to marmoset chromosomes. Because, at present, there is the confusion situation of several different numbering systems for marmoset chromosomes, we propose a new simpler nomenclature based on descending order of chromosome size.
journal_name
Genomicsjournal_title
Genomicsauthors
Sherlock JK,Griffin DK,Delhanty JD,Parrington JMdoi
10.1006/geno.1996.0186subject
Has Abstractpub_date
1996-04-15 00:00:00pages
214-9issue
2eissn
0888-7543issn
1089-8646pii
S0888-7543(96)90186-Xjournal_volume
33pub_type
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