Abstract：
:In decerebrate rats, the responses of tilt-sensitive neurons in the lateral and descending vestibular nuclei were studied during constant velocity 10 degrees off-vertical axis rotations (OVAR) in the clockwise (VW) and counterclockwise (CCW) directions. Seventy three otolith-related units showed a sinusoidal position-dependent discharge modulation to OVAR of both directions; 20 of these showed clipped firing rates in parts of a 360 degree OVAR cycle. With increase in the velocity of rotation (1.75-15 degrees/s), one group of units (n = 36) showed a stable ratio of bidirectional response sensitivity and symmetric response magnitudes to CW and CCW rotations. These units showed gain tuning ratios similar to those of narrowly spatiotemporal-tuned neurons. The other group of OVAR responsive units (n = 13) exhibited velocity-variable and asymmetric bidirectional response sensitivities. Their gain tuning ratios were similar to those of broadly spatiotemporal-tuned neurons. For units with velocity-stable and symmetric bidirectional response sensitivity as well as gain tuning ratio of the narrowly spatiotemporal-tuned neurons, their response gains remained stable with velocity. Some showed stable response phase lead or lag with velocity increase while others showed progressive shifts from response lead of 13 degrees to response lag of -25 degrees. The best response orientations of these units with velocity-stable and symmetric bidirectional response sensitivity were found to point in all directions on the place of rotation. The functional significance of these tilt- and OVAR-sensitive central otolith neurons is discussed.
journal_name
Brain Resjournal_title
Brain researchauthors
Lai CH,Chan YSdoi
10.1016/0006-8993(95)00687-lsubject
Has Abstractpub_date
1995-09-25 00:00:00pages
39-50issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(95)00687-Ljournal_volume
693pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:The purpose of this study was to investigate morphological characteristics of the synaptic relations of choline acetyltransferase (ChAT)-positive terminals that are made with a variety of post-synaptic profiles in the lateralis medialis-suprageniculate nuclear complex (LM-Sg) using ChAT, gamma-aminobutyric acid (GABA)...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(96)01208-5
更新日期：1997-01-30 00:00:00
abstract：:The neurotoxic effects produced by ibotenic acid (IA) induced chemical lesions of the central nervous system (CNS) cholinergic system were examined on the opioid peptidergic system in adult rats. Forebrain cholinergic systems were bilaterally lesioned by the infusion of IA (1 or 5 micrograms/site) into the nucleus bas...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90668-y
更新日期：1992-02-07 00:00:00
abstract：:Animal and cell experiments showed that inositol hexaphosphate (IP6) was protective on neurons in parkinson's disease (PD) model, but the underlying mechanism of this action was not extensively elucidated. To address this question, we established 6-hydroxydopamine (6-OHDA) induced human dopaminergic cell line SH-SY5Y ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.12.035
更新日期：2016-02-15 00:00:00
abstract：:In vitro uptake of labeled serotonin (5-HT) has allowed the radioautographic detection of serotoninergic fibers in the cat spinal cord at thoracic and lumbar levels. The specificity of labeling was ensured by the conditions of incubation ([3H]5-HT was 10(-7) M) and by test control experiments with concomitant 10(-6) M...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(78)90331-1
更新日期：1978-09-29 00:00:00
abstract：:The L-isomer of beta-N-methylamino-L-alanine (BMAA), present in free form in seed of Cycas circinalis, elicits in spinal cord cultures a pattern of acute postsynaptic neuronal vacuolation comparable to that induced by beta-N-oxalylamino-L-alanine (BOAA), an excitotoxic amino acid of greater potency isolated from seed ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90342-8
更新日期：1987-05-05 00:00:00
abstract：:In order to identify fixed versus flexible aspects of swallowing and oromotor control, we developed a method for the concurrent analysis of swallow frequency, swallow volume, and the temporal correlation between swallowing and rhythmic orolingual movements during prolonged bouts of fluid ingestion in unanesthetized, u...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)91135-9
更新日期：1989-10-09 00:00:00
abstract：:The effect of an 8% casein and a control 25% casein diet on the granule cells in the dorsal blade of the dentate gyrus of the rat hippocampal formation was studied at 30, 90 and 220 days of age. Female rats were fed either an 8% or 25% casein diet 5 weeks prior to conception and the litters were maintained on these re...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91769-d
更新日期：1990-11-05 00:00:00
abstract：:Previous studies found that injection of the GABA uptake inhibitor nipecotic acid into the nucleus tractus solitarius (NTS) increases arterial pressure. This effect of nipecotic acid was not antagonized by the selective GABAA receptor blocking agent bicuculline, suggesting that the action of nipecotic acid was mediate...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91227-8
更新日期：1990-09-03 00:00:00
abstract：:Systemic administration of nicotinic receptor (nAChR) agonists is antinociceptive in models of acute pain whereas their intrathecal (i. t.) administration has been reported to be antinociceptive, nociceptive or without effect. It has been hypothesized that the action induced is dependent upon the subtype and location ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02472-0
更新日期：2000-07-28 00:00:00
abstract：:After injections of 6-hydroxydopamine (6-OHDA) along the medial forebrain bundle in the lateral hypothalamus, rats failed to acquire a one-way active avoidance response or failed to perform a previously acquired active avoidance response. Such rats, however, acquired a passive avoidance response and a conditioned tast...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(75)90659-9
更新日期：1975-05-09 00:00:00
abstract：:Saccadic eye tracking was studied in a monkey given i.v. injections of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The Parkinson-like symptoms which appeared in the animal's general motor behavior (akinesia, bradykinesia, hypokinesia) were also observed in its eye tracking. Similar oculomotor deficits are see...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90049-1
更新日期：1986-09-24 00:00:00
abstract：:Three groups of rats, one with amygdala lesions, one with hippocampal lesions and a control group were trained on a brightness discrimination task under one of three different conditions, enhancement of the negative cue, enhancement of the positive cue or a non-enhanced condition. Animals with amygdala lesions showed ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(77)90621-7
更新日期：1977-04-15 00:00:00
abstract：:Swelling of glial and nerve cells is characteristic of brain damage in cerebral ischemia or trauma. The therapeutical efficiency of inhibition of Cl(-)-transport by a novel antagonist, the diuretic torasemide, on cytotoxic swelling of glial cells from lactacidosis, or glutamate was analyzed. Lactacidosis and the inter...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91218-h
更新日期：1993-04-30 00:00:00
abstract：:Epileptic discharge patterns in an acute experimental model of epilepsy were analyzed. Epileptic foci were induced by epicortical application of penicillin on the rat motor cortex in vivo. Patterns with regular 1/s discharges, patterns with irregular discharges of about 0.5/s as well as compound patterns comprising di...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90221-8
更新日期：1993-07-09 00:00:00
abstract：:Microencephalic rats induced by methylazoxymethanol (MAM) were observed to have notable hyperactivity compared to control rats, as measured by several behavioral parameters in an automated field apparatus. Acute injection of the stimulant drug, methamphetamine (MAP), produced an increase in the incidence of locomotion...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)01307-4
更新日期：1995-01-23 00:00:00
abstract：:A cluster of trigeminal nociceptive neurons was located in the lateral sulcus on the upper bank of the frontoparietal operculum in a region bordering between cortical areas SII and 7b. These neurons were isolated in cortical cell layers IV and V-VI. All nociceptive neurons responded exclusively to noxious mechanical s...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90375-2
更新日期：1989-04-10 00:00:00
abstract：:Painful experience is a complex entity made up of sensory, affective, motivational and cognitive dimensions. The neural mechanisms involved in pain perception acts in a serial and a parallel way, discriminating and locating the original stimulus and also integrating the affective feeling, involved in a special situati...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2003.10.073
更新日期：2004-03-12 00:00:00
abstract：:Cell death was due to activation of the receptor responsive to N-methyl-D-aspartate (NMDA). Even during a 30-min incubation, glutamate toxicity was unaffected by 5 microM CNQX and was greater than 90% blocked by 160 nM MK-801, a specific antagonist of the NMDA receptor. The extent of toxicity was dependent on the age ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)91244-u
更新日期：1991-09-27 00:00:00
abstract：:A technique was developed for the quantitative regional assessment of brain pH by a modification of the umbelliferone method. Twenty micron thick sections were brought into contact with umbelliferone-soaked paper strips and the fluorescence (450 nm) following excitation at 370 nm and 340 nm was recorded photographical...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90037-9
更新日期：1983-12-19 00:00:00
abstract：:To examine the structural interactions between synaptically connected neurons in Aplysia, we have developed a method for simultaneously labeling two identified cell with different and compatible intraneuronal marking agents (horseradish peroxidase and [3H]N-acetyl-D-galactosamine) visible in both the light and electro...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(79)90621-8
更新日期：1979-09-14 00:00:00
abstract：:The dynamics of regional cerebral blood flow and brain extracellular glucose were studied in the freely moving rat. These two variables were measured in the striatum during and following both mild tail pinch and restraint stress. Blood flow was monitored using a refinement of the hydrogen clearance technique that allo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90373-u
更新日期：1993-02-26 00:00:00
abstract：:Systemic injection of kainic acid (KA) in adult rat elicits a pattern of neuronal pathology which exhibits several features of human temporal lobe epilepsy. KA-induced seizure activity is accompanied by the activation of the calcium-dependent protease calpain in limbic structures. In the present study, we evaluated th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)01360-1
更新日期：1996-07-08 00:00:00
abstract：:Evolutionary selection pressures have been one of the factors proposed to underlie sex differences in inhibitory control. Consequently, inhibitory control may vary as a function of the menstrual cycle and may be modulated by the stimuli being processed if these stimuli are related to reproductive success. We used func...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.05.061
更新日期：2008-08-11 00:00:00
abstract：:alpha-Adrenoreceptors are present in the ventricular (VZ) and subventricular (SVZ) zones of the mammalian embryonic forebrain, and contribute towards cell cycle controls in the germinal neuroepithelium [Pabbathi et al., Brain Res. 760 (1997) 22-33.]. Since noradrenaline-containing fibres from the locus coeruleus (LC) ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)02242-8
更新日期：2000-01-24 00:00:00
abstract：:Genetic variability in the behavioral responses of experimental subjects to psychostimulants such as amphetamine and cocaine have been reported. However, genetic differences in the locomotor responses of rat strains to methylphenidate (MPD), a commonly used psychostimulant in the treatment of attention deficit/hyperac...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)04240-3
更新日期：2003-05-09 00:00:00
abstract：:Cytochemistry was used to examine the distribution of two pathways of utilization of hydrogen (Type I and Type II H) generated by glucose-6-phosphate dehydrogenase (G6PD) in circumventricular organs (CVOs) and the hypothalamo-neurohypophysial system in cryostat sections of rat brain. Type I H is defined as that portio...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)91306-4
更新日期：1984-02-27 00:00:00
abstract：:The purpose of this review is to provide strategies and their rationale which can facilitate scientifically productive investigations into genetic, neuronal, brain functional and clinical aspects of bipolar disorder. The presentation addresses both factors that have impeded and those that have facilitated landmark adv...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2008.05.084
更新日期：2008-10-15 00:00:00
abstract：:Transfer learning is an immanent feature of perceptual learning. Yet, despite the increasingly widespread application of transcranial direct current stimulation (tDCS) to study learning, transfer effects in response to tDCS have not been studied. Therefore, the present study investigated the transfer of tactile acuity...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2018.03.031
更新日期：2018-06-15 00:00:00
abstract：:Significant insights into the dynamics of neuronal populations have been gained in the olfactory system where rich spatio-temporal dynamics is observed during, and following, exposure to odours. It is now widely accepted that odour identity is represented in terms of stimulus-specific rate patterning observed in the c...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.07.032
更新日期：2012-01-24 00:00:00
abstract：:Hypothalamic nuclei close to the third ventricle (VIII) represent key structures in avian osmoregulation concerned with the control of salt gland activity and release of the antidiuretic hormone [Arg8]vasotocin (AVT). Nitric oxide (NO) acting as a paracrine transmitter in the hypothalamus has been shown to contribute ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01205-6
更新日期：1999-04-17 00:00:00
