Abstract：
AIM:It is routine practice to prolong the incubation period of blood cultures from patients with suspected subacute bacterial endocarditis (SBE) or fungal infection. The protocol in this laboratory required 28 days incubation with weekly subcultures. Following the introduction of automated continuously monitored blood culture instruments, the duration of incubation for specimens from these categories of patients was reviewed. METHOD:In a retrospective study of blood culture specimens submitted from 1 July 1994 to 31 July 1998, the time from collection to a positive signal from the BacT/Alert automated blood culture system, in patients suspected of SBE or fungal infection, was assessed. RESULTS:From 355 patient episodes, 896 bottles were incubated for up to 28 days, during which time 116 bottles (40 patient episodes) signalled positive. Significant organisms from suspected endocarditis patients were isolated from 87 bottles (87%), with the time to detection ranging from 9 to 96 hours. The data collected from significant isolates obtained from clinically suspected fungaemias were extremely small, prompting a review of the total fungal isolates from all blood culture bottles incubated during the study period. Yeast isolates were obtained from 78 (0.08%) bottles with the detection time ranging from 15 to 144 hours. CONCLUSION:The practice in this laboratory now is to incubate blood cultures for up to 7 days when the clinical notes indicate the possibility of SBE or a fungal infection.
journal_name
Pathologyjournal_title
Pathologyauthors
Varettas K,Taylor PC,Mukerjee Cdoi
10.1080/003130201201117981subject
Has Abstractpub_date
2002-04-01 00:00:00pages
167-9issue
2eissn
0031-3025issn
1465-3931journal_volume
34pub_type
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