Abstract:
:Cross-correlation experiments allow to obtain information about synaptic potentials in human motoneurons. However, recording cross-correlation responses of one motoneuron to transcranial magnetic and electrical peripheral nerve stimulation requires a considerable recording time when both responses are recorded consecutively. In this paper a method is introduced yielding the same information about the responses of a single motoneuron to both types of stimuli while requiring only a fraction of the recording time necessary for a conventional cross-correlation experiment. The main features of the method introduced were: (i) use of the recharging time of the magnetic stimulator for response recording to the electrical stimulus, (ii) use of specific stimulus timing with respect to the motor unit discharges, and (iii) on-line display with statistical testing of the response functions allowing to stop stimulus application, if the responses to both types of stimuli had reached statistical significance. Application of the method is demonstrated with response recording of 70 tibialis anterior motor units from five healthy volunteers to transcranial magnetic and peroneal nerve electrical stimulation.
journal_name
J Neurosci Methodsjournal_title
Journal of neuroscience methodsauthors
Awiszus F,Feistner Hdoi
10.1016/0165-0270(95)00028-ssubject
Has Abstractpub_date
1995-09-01 00:00:00pages
91-7issue
1-2eissn
0165-0270issn
1872-678Xpii
0165-0270(95)00028-Sjournal_volume
61pub_type
杂志文章abstract:INTRODUCTION:Our aim was to assess differences in movement measures in attention-deficit/hyperactivity disorder (ADHD) vs. typically developing (TD) controls. METHODS:We performed meta-analyses of published studies on motion measures contrasting ADHD with controls. We also conducted a case-control study with children/...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章,meta分析
doi:10.1016/j.jneumeth.2015.03.001
更新日期:2015-08-30 00:00:00
abstract::The whole cell patch clamp technique allows recording of membrane currents in an entire cell under voltage clamp conditions. However, technical difficulties arise in large cells bearing extensive processes, such as human fetal dorsal root ganglion (DRG) neurons in culture. In order to improve space clamp conditions, h...
journal_title:Journal of neuroscience methods
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doi:10.1016/0165-0270(90)90094-v
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abstract::The immunotoxin 192 IgG-saporin has a high degree of selectivity for cholinergic neurons within the basal forebrain (CBF). Intracerebroventricular delivery of 192 IgG-saporin results in a diffuse and massive depletion of choline acetyltransferase (ChAT) activity in projections of the CBF, and non-selective loss of Pur...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/s0165-0270(99)00057-6
更新日期:1999-09-15 00:00:00
abstract::Experimental recordings from neurons are generally difficult to quantify. Spike patterns and membrane potential cycles are often compared qualitatively and are hence limited by human resolution and judgement. This paper describes a statistical method for quantifying individual spike patterns and membrane potential flu...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/0165-0270(93)90053-t
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abstract::Recently, resting state functional connectivity (RSFC) studies based on fMRI and EEG/MEG have provided valuable insight into the intrinsic functional architecture of the human brain. However, whether functional near infrared spectroscopy (fNIRS), a suitable imaging method for infant and patient populations, can be use...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
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更新日期:2010-02-15 00:00:00
abstract::Skeletal muscle is a convenient model system for studying basic questions on the neural regulation of synaptogenesis and of many properties of sarcolemma and contractile apparatus. The study of the neural signals involved in a particular regulation and of the mediating intracellular pathways, requires the chronic appl...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/s0165-0270(00)00352-6
更新日期:2001-04-30 00:00:00
abstract::Transcranial Electrical Stimulation (tES) encompasses all methods of non-invasive current application to the brain used in research and clinical practice. We present the first comprehensive and technical review, explaining the evolution of tES in both terminology and dosage over the past 100 years of research to prese...
journal_title:Journal of neuroscience methods
pub_type: 历史文章,杂志文章,评审
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更新日期:2013-10-15 00:00:00
abstract::Although dopamine (DA) translocation by the DA transporter (DAT) requires Na+, a role for Na+ in the DA recognition step in the translocation cycle has been questioned. Thus, when binding techniques were used to indirectly measure the affinity of DA for DAT via its potency in inhibiting cocaine analog binding, no stim...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/s0165-0270(03)00230-9
更新日期:2003-12-30 00:00:00
abstract::To facilitate the combination of optical imaging with various electrode-based techniques, we have designed and produced a skull-mounting "sliding-top cranial window" and a removable "electrode positioner microdrive". These new devices were used to study sensory processing in chronic and acute experiments in the cerebr...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/s0165-0270(02)00022-5
更新日期:2002-04-30 00:00:00
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journal_title:Journal of neuroscience methods
pub_type: 杂志文章
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更新日期:2011-04-30 00:00:00
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journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/s0165-0270(96)00158-6
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND:Wireless neural recording technologies now provide untethered access to large populations of neurons in the nonhuman primate brain. Such technologies enable long-term, continuous interrogation of neural circuits and importantly open the door for chronic neurorehabilitation platforms. For example, by providin...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/j.jneumeth.2017.06.013
更新日期:2017-08-15 00:00:00
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journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/j.jneumeth.2004.10.001
更新日期:2005-04-30 00:00:00
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journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/j.jneumeth.2007.06.020
更新日期:2007-10-15 00:00:00
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journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/s0165-0270(97)00063-0
更新日期:1997-07-18 00:00:00
abstract:BACKGROUND:The ongoing crisis related to non-medical use of opioids makes it of continued importance to understand the risk factors for opioid addiction, the behavioral and neurobiological consequences of opioid exposure and to seek potential avenues for therapy. Pre-clinical rodent models have been critical to advanci...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/j.jneumeth.2020.108993
更新日期:2021-01-15 00:00:00
abstract::Many neurophysiological experiments on rodents and non-human primates involve the implantation of more than one multi-electrode array to record from many regions of the brain. So called 'floating' microelectrode arrays are implanted in cortical regions of interest and are coupled via a flexible cable to their connecto...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/j.jneumeth.2010.02.006
更新日期:2010-05-15 00:00:00
abstract::A combination of two procedures, embedding of specimens and horseradish peroxidase (HRP) histochemistry on mounted serial sections, is proposed for three-dimensional reconstruction of neuronal projections. To clarify the intrinsic organization of the peripheral nervous system, this simple method is more adequate than ...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/0165-0270(86)90130-5
更新日期:1986-09-01 00:00:00
abstract::A newly designed combination microelectrode-injection system is described which can be used to record electrophysiological responses of individual neurons in the primate brain to local administration of small quantities of drugs or other compounds. The assembly of the system is simple, and the materials used are inexp...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/j.jneumeth.2004.03.015
更新日期:2004-09-30 00:00:00
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journal_title:Journal of neuroscience methods
pub_type: 杂志文章
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更新日期:1985-05-01 00:00:00
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journal_title:Journal of neuroscience methods
pub_type: 杂志文章
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journal_title:Journal of neuroscience methods
pub_type: 杂志文章
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journal_title:Journal of neuroscience methods
pub_type: 杂志文章
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更新日期:2013-04-15 00:00:00
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journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/0165-0270(88)90173-2
更新日期:1988-07-01 00:00:00
abstract::The event-related potential (ERP) and event-related field (ERF) techniques provide valuable insights into the time course of processes in the brain. Because neural signals are typically weak, researchers commonly filter the data to increase the signal-to-noise ratio. However, filtering may distort the data, leading to...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
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更新日期:2012-07-30 00:00:00
abstract::The glycogen-depletion technique has become a well-established method for determining histologically the cross-sectional distribution of a single muscle unit. A major drawback of this method is its low yield of one depleted unit per experiment. Furthermore, this technique is particularly unsuited for determining the l...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
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更新日期:1987-10-01 00:00:00
abstract:BACKGROUND:Application of functional Near InfraRed Spectroscopy (fNIRS) in neurology is still limited as a good optical coupling and optimized optode coverage of specific brain regions remains challenging, notably for prolonged monitoring. METHODS:We propose to evaluate a new procedure allowing accurate investigation ...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/j.jneumeth.2018.08.006
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:Deep brain stimulation (DBS) has treatment efficacy in neurological and psychiatric disorders such as Parkinson's disease and major depression. Electroencephalography (EEG) is a versatile neurophysiological tool that can be used to better understand DBS treatment mechanisms. DBS causes artifacts in EEG recor...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
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更新日期:2014-11-30 00:00:00
abstract::Following bilateral injection of manganese (Mn) into the rat's motor cortex, electrical stimulation of the cortex is shown to increase the transport, uptake and accumulation of Mn in the corticospinal tract (CST), as assessed by manganese-enhanced magnetic resonance imaging (MEI). T(1)-weighted gradient echo images we...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
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abstract::A method is described for the production of an electrode capable of monitoring and modulating the input-output relationship of thalamic neurons. Tungsten-in-glass electrodes were manufactured with the ability to simultaneously record lateral geniculate nucleus action potentials and associated, retinally evoked S-poten...
journal_title:Journal of neuroscience methods
pub_type: 杂志文章
doi:10.1016/0165-0270(93)90126-c
更新日期:1993-09-01 00:00:00