Abstract:
:The recently described murine homeobox genes, Six1 and Six2, which are expressed during development in limb tendons, have also been shown to be expressed in skeletal and smooth muscle, respectively. We have cloned and sequenced a human SIX1 cDNA and shown by Northern blotting that it is expressed in adult skeletal muscle. The cDNA sequence and predicted protein sequence of SIX1 and Six1 are highly homologous, with 98% similarity over the entire predicted amino acid sequence. SIX1 was mapped to human chromosome 14 using a rodent/human somatic cell hybrid panel.
journal_name
Genomicsjournal_title
Genomicsauthors
Boucher CA,Carey N,Edwards YH,Siciliano MJ,Johnson KJdoi
10.1006/geno.1996.0172subject
Has Abstractpub_date
1996-04-01 00:00:00pages
140-2issue
1eissn
0888-7543issn
1089-8646pii
S0888-7543(96)90172-Xjournal_volume
33pub_type
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