Endocrine regulation of subcutaneous fat metabolism during cold exposure in humans.

abstract：:A diagnostic test is particularly beneficial if it reveals the level of susceptibility prior to onset of a disease process. In the case of childhood caries, such a diagnostic test affords the opportunity for preventive measures to be implemented before caries begins. Salivary glycoproteins contain a wealth of individu...

journal_title：Annals of the New York Academy of Sciences

authors： Denny PC,Denny PA,Takashima J,Galligan J,Navazesh M

更新日期：2007-03-01 00:00:00

abstract：:The hyperactivation of glutamate receptors, especially those of the N-methyl-d-aspartate subtype (NMDA), can induce excess calcium entry into cells, leading to neuronal death. Since the anesthetic gas xenon behaves as an NMDA antagonist, the present article investigated, by distinct morphological approaches and after ...

journal_title：Annals of the New York Academy of Sciences

authors： Natale G,Cattano D,Abramo A,Forfori F,Fulceri F,Fornai F,Paparelli A,Giunta F

更新日期：2006-08-01 00:00:00

abstract：:The vast majority of what is known about the neural underpinnings of human cognition comes from studies limited to racially, ethnically, and socioeconomically homogeneous samples. Furthermore, although most studies include both males and females in their samples, sex differences in patterns of brain activity and perfo...

journal_title：Annals of the New York Academy of Sciences

authors： Dotson VM,Duarte A

更新日期：2020-03-01 00:00:00

abstract：:The entry of resting T cells into the G1 phase of the cell cycle after stimulation by mitogens is controlled by a series of biochemical events that are independent of growth factors. These events follow the initial signals stimulated through the engagement of the T-cell receptor and include activation of the cyclin-de...

journal_title：Annals of the New York Academy of Sciences

authors： Modiano JF,Domenico J,Szepesi A,Terada N,Lucas JJ,Gelfand EW

更新日期：1995-09-07 00:00:00

abstract：:Disorders of sexual differentiation (DSDs) presenting during adolescence are discussed, and molecular explanations are given for some. DSD conditions are often discovered during early adolescence, an age well known to predispose to high risk for adjustment problems. Presentation may be with lack of or minimal pubertal...

journal_title：Annals of the New York Academy of Sciences

authors： Lee PA,Houk CP

更新日期：2008-01-01 00:00:00

abstract：:The selective expression of a gene is achieved through the interaction of protein transcription factors with characteristic DNA sequences located in the regulatory region of the gene, which is usually distinct from the coding region. These proteins contain domains that bind specifically to the DNA sites (or response e...

journal_title：Annals of the New York Academy of Sciences

authors： Klug A

更新日期：1995-06-30 00:00:00

abstract：:Glucose conversion by brain synaptosomes can be regarded as a special case of intrinsic kinetic properties of the enzyme substrate system. Temperature modulation of apparent K(m) for this process can be described with our kinetic model. Using experimental data and the kinetic model, the minimal K(m) value for glucose ...

journal_title：Annals of the New York Academy of Sciences

authors： Marjanović M,Zivadinović D,Dzakula Z,Andjus RK

更新日期：2005-06-01 00:00:00

abstract：:The mobilization and recruitment of blood and lymphatic vasculatures are widely described in inflammatory bowel diseases (IBDs). Although angiogenesis contributes to intense gut inflammation, it remains unclear whether and when lymphangiogenesis amplifies or protects in IBD. The prolonged maintenance of lymphatic (ove...

journal_title：Annals of the New York Academy of Sciences

authors： Alexander JS,Chaitanya GV,Grisham MB,Boktor M

更新日期：2010-10-01 00:00:00

abstract：:Many therapeutic options exist for the management of patients with Ménière's disease. In the last few years, the use of intratympanic gentamicin has been investigated as an alternative treatment to vestibular nerve section or labyrinthectomy. In humans, the concentration of gentamicin used for intratympanic treatment ...

journal_title：Annals of the New York Academy of Sciences

authors： Quaranta A,Aloisi A,De Benedittis G,Scaringi A

更新日期：1999-11-28 00:00:00

abstract：:In this paper, the topic of laminar to turbulent flow transition, as applied to the design of gas turbines, is discussed. Transition comes about when a flow becomes sufficiently unstable that the orderly vorticity structure of the laminar layer becomes randomly oriented. Vorticity with a streamwise component leads to ...

journal_title：Annals of the New York Academy of Sciences

authors： Simon TW,Kaszeta RW

更新日期：2001-05-01 00:00:00

abstract：:Throughout this century in the United States, tension has existed between those who believe drug abuse is best combatted through the criminal justice system and those who emphasize a medical/public health model of prevention and treatment. In the last decade this debate has centered around the person of the pregnant a...

journal_title：Annals of the New York Academy of Sciences

authors： Chavkin W,Wise PH,Elman D

更新日期：1998-06-21 00:00:00

abstract：:Masting, the highly variable and synchronous production of seeds across a population of perennial plants, is an ecologically important, but still poorly understood, phenomenon. While much is known about the fitness benefits of masting and its effects on seed consumers and trophic interactions, less is understood about...

journal_title：Annals of the New York Academy of Sciences

authors： Crone EE,Rapp JM

更新日期：2014-08-01 00:00:00

abstract：:We test whether inhibition of inducible nitric oxide synthase (iNOS) can exert a cytoprotective effect on cerebral endothelial cells upon stimulation by pro-inflammatory cytokines. Mouse brain endothelial cells were stably transfected to express an antisense RNA against iNOS driven by an endothelium-specific von Wille...

journal_title：Annals of the New York Academy of Sciences

authors： Yang DI,Chen S,Ezekiel UR,Xu J,Wu Y,Hsu CY

更新日期：2005-05-01 00:00:00

abstract：:Adult (3-month-old) and aged (28-month-old) rats that had been pretreated with 5,7-DHT in both lateral ventricles received grafts of cell suspensions taken from the RR or MR regions taken from the embryonic stages E12-21. These cell suspensions were implanted unilaterally into the rostral part of the hippocampus or th...

journal_title：Annals of the New York Academy of Sciences

authors： Steinbusch HW,Beek A,Frankhuyzen AL,Tonnaer JA,Gage FH,Björklund A

更新日期：1987-01-01 00:00:00

abstract：:We previously showed that pituitary adenylate cyclase-activating polypeptide (PACAP) potently stimulates insulin secretion in vivo in mice without altering glucose disposal. Such a combination of results would be explained if epinephrine released by PACAP counteracts the action of insulin and, therefore, that the gluc...

journal_title：Annals of the New York Academy of Sciences

authors： Ahrén B,Filipsson K

更新日期：2000-01-01 00:00:00

abstract：:Modern neurostimulation approaches in humans provide controlled inputs into the operations of cortical regions, with highly specific behavioral consequences. This enables causal structure-function inferences, and in combination with neuroimaging, has provided novel insights into the basic mechanisms of action of neuro...

journal_title：Annals of the New York Academy of Sciences

authors： Bestmann S,Feredoes E

更新日期：2013-08-01 00:00:00

abstract：:We have examined the expression of several genes whose transcripts have increased levels in Alzheimer's disease and have found heterogeneity in these levels in different patients with this condition. The level of expression of these genes was compared to different clinical and pathological aspects of the disease. A ca...

journal_title：Annals of the New York Academy of Sciences

authors： Duguid JR,Trzepacz C,Kemper T,Tourtellote WW,Volicer L

更新日期：1993-05-28 00:00:00

abstract：:The existence of a covalent intermediate in topoisomerase I catalysis allows uncoupling of the cleavage and ligation half-reactions on partially single-stranded DNA substrates containing a highly preferred interaction site. Using this model DNA substrate system we have demonstrated that the cleavage reaction requires ...

journal_title：Annals of the New York Academy of Sciences

authors： Christiansen K,Westergaard O

更新日期：1996-12-13 00:00:00

abstract：:To investigate the role of zinc and copper in the development of pseudoexfoliation (PSX) syndrome, 34 cataract patients with PSX syndrome and 27 cataract patients without PSX syndrome were included in the study and groups were matched for age and gender. During the cataract surgery, lenses were obtained intraoperative...

journal_title：Annals of the New York Academy of Sciences

authors： Yildirim Z,Uçgun NI,Kiliç N,Gürsel E,Sepici-Dinçel A

更新日期：2007-04-01 00:00:00

abstract：:Stroke is a common and often fatal event, and, in survivors, it is accompanied by a high risk of recurrence. Ischemic stroke is associated with abnormal platelet activity and thrombus formation. In addition to their roles in the development of acute thrombi, platelets serve as a bridge for leukocytes within the vascul...

journal_title：Annals of the New York Academy of Sciences

authors： Franks ZG,Campbell RA,Weyrich AS,Rondina MT

更新日期：2010-10-01 00:00:00

abstract：:The recent identification of lymphatic endothelial cell-specific markers and the generation of mouse models harboring mutations in many genes that encode those markers have enabled us to begin to elucidate the developmental steps that go toward establishing the lymphatic vasculature network. Understanding these basic ...

journal_title：Annals of the New York Academy of Sciences

authors： Oliver G,Srinivasan RS

更新日期：2008-01-01 00:00:00

abstract：:As studied by single cell RT-PCR of pituitary hormones, we demonstrated that the pituitaries of rats and mice contain a subpopulation of cells that express two or more hormone phenotypes typically belonging to lineages that are branched separately early during embryonic development, such as glycoprotein hormone alpha-...

journal_title：Annals of the New York Academy of Sciences

authors： Denef C,Pals K,Hauspie A,Vankelecom H,Seuntjens E

更新日期：2005-04-01 00:00:00

abstract：:Heparins represent an efficient treatment of acute thrombosis and obstetric complications in antiphospholipid syndrome (APS). Enhanced microvesiculation of cell membranes, as detected by reduced membrane adhesion, can contribute to hypercoagulability in APS. Healthy donor IgG antibodies significantly increased beta2-g...

journal_title：Annals of the New York Academy of Sciences

authors： Frank M,Sodin-Semrl S,Rozman B,Potocnik M,Kralj-Iglic V

更新日期：2009-09-01 00:00:00

abstract：:The results of this study indicate that the presence of plants did enhance TNT and TNB removal from IAAP groundwater. Most effective at 25 degrees C were reed canary grass, coontail and pondweed. Groundwater and plant tissue analyses indicate that in presence of the plants tested TNT is degraded to reduced by-products...

journal_title：Annals of the New York Academy of Sciences

authors： Best EP,Zappi ME,Fredrickson HL,Sprecher SL,Larson SL,Ochman M

更新日期：1997-11-21 00:00:00

abstract：:The envelope glycoprotein complex (Env), encoded by the human immunodeficiency virus (HIV-1), kills uninfected cells expressing CD4 and/or the chemokine receptor CXCR4 or CCR5, via at least three independent mechanisms. First, the soluble Env product gp120 can induce the apoptotic cell death of lymphocytes, neurons, a...

journal_title：Annals of the New York Academy of Sciences

authors： Castedo M,Perfettini JL,Andreau K,Roumier T,Piacentini M,Kroemer G

更新日期：2003-12-01 00:00:00

abstract：:N-type calcium channels both generate the initial calcium signal to trigger neurotransmitter release and also interact with synaptic release proteins at many mammalian central nervous system synapses. Two isoforms of the alpha 1B N-type channel from rat brain (alpha 1B-I and alpha 1B-II) were found to differ in four r...

journal_title：Annals of the New York Academy of Sciences

authors： Stea A,Dubel SJ,Snutch TP

更新日期：1999-04-30 00:00:00

abstract：:In type 1 diabetes mellitus (T1DM), the frequency of antibodies against insulin (IAA), glutamic acid decarboxylase-65 (GAD65), ICA512/IA2 (IA2), and islet cell antigens (ICA) vary with human leukocyte antigen (HLA) composition of the patient. IAA, IA2 autoantibodies, and ICA are increased in DQ8 positives; GAD65 antib...

journal_title：Annals of the New York Academy of Sciences

authors： Gupta M,Graham J,McNeeny B,Zarghami M,Landin-Olsson M,Hagopian WA,Palmer J,Lernmark A,Sanjeevi CB

更新日期：2006-10-01 00:00:00

abstract：:Propofol is a widely used intravenous anesthetic agent. Our previous study showed that a therapeutic concentration of propofol can modulate macrophage functions. Mitochondria play critical roles in the maintenance of macrophage activities. This study attempted to evaluate further the effects of mitochondria on the pro...

journal_title：Annals of the New York Academy of Sciences

authors： Wu GJ,Tai YT,Chen TL,Lin LL,Ueng YF,Chen RM

更新日期：2005-05-01 00:00:00

abstract：:The development of an integrated system for the continuous, automated production of pure cell culture derived proteins is discussed. The system comprises a cell culture subunit for the continuous culture of mammalian cells and a purification subunit linked on-line to the cell culture subunit. The cells are compartment...

journal_title：Annals of the New York Academy of Sciences

authors： Grandics P,Szathmary S,Szathmary Z,O'Neill T

更新日期：1991-12-27 00:00:00

abstract：:The computation of ITD begins with preservation of the phase angle of spectral components by eighth-nerve fibers and by cells of the nucleus magnocellularis. At the level of the nucleus laminaris, the difference in phase angle of corresponding spectral components in the left and right ears is extracted. At the next le...

journal_title：Annals of the New York Academy of Sciences

authors： Takahashi TT

更新日期：1989-01-01 00:00:00