Acetazolamide therapy for symptomatic plateau waves in patients with brain tumors. Report of three cases.

Abstract:

:In this report, the authors describe three patients with malignant gliomas who experienced paroxysmal neurological symptoms triggered by standing. The symptoms were attributed to acute elevations of intracranial pressure, an uncommon phenomenon called "plateau waves." In each instance, the attacks occurred despite the fact that the patient was receiving dexamethasone therapy and stopped promptly with the addition of acetazolamide. Acetazolamide, an orally administered carbonic anhydrase inhibitor, appears to be a specific and effective therapy for this uncommon neurological disorder.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Watling CJ,Cairncross JG

doi

10.3171/jns.2002.97.1.0224

subject

Has Abstract

pub_date

2002-07-01 00:00:00

pages

224-6

issue

1

eissn

0022-3085

issn

1933-0693

journal_volume

97

pub_type

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