Abstract:
:Experiments were designed to test whether nonrandom segregation of sister chromatids at mitosis has a role in the production of cell diversity during embryogenesis, Segregation was examined in vivo in retinal cells from embryonic chicks. Chromatids were labelled with bromouracil and stained by the fluorescence plus Giemsa technique. No evidence of nonrandom segregation was observed in a frequency distribution of pairs of bifilarly labelled sister chromatids at the third metaphase after the start of labeling. Nor was there evidence that chromatids from homologous chromosomes segregated nonrandomly. Nonrandom segregation is probab;y not a mechanism for cell diversification.
journal_name
Chromosomajournal_title
Chromosomaauthors
Morris VBdoi
10.1007/BF00288461subject
Has Abstractpub_date
1977-03-16 00:00:00pages
139-45issue
2eissn
0009-5915issn
1432-0886journal_volume
60pub_type
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