Abstract:
:Three patients with severe traumatic brain injury demonstrated significant improvement in arousal and initiation after administration of tricyclic antidepressants. The first patient showed improved motor and speech initiation in response to amitriptyline following several months of functional plateau. The second patient was minimally responsive 2 months after injury and demonstrated improved arousal following the use of desipramine. Both patients deteriorated when the medications were discontinued and improved again when they were restarted. These two cases provide strong evidence for a medication effect. The third patient began to verbalize following desipramine administration, despite being mute for more than a year after injury. Previous case reports describe cognitive-enhancing effects, such as improved arousal, attention, memory, and initiation, of dopaminergic agents, and in the case of tricyclic antidepressants, effects on agitation. The role of norepinephrine in promoting neurological recovery after brain lesions has been demonstrated in animals. The cases presented here provide some of the first data to show similar efficacy in humans and underscore the need for controlled trials to better determine which patients will benefit.
journal_name
Arch Phys Med Rehabiljournal_title
Archives of physical medicine and rehabilitationauthors
Reinhard DL,Whyte J,Sandel MEdoi
10.1016/s0003-9993(96)90225-7subject
Has Abstractpub_date
1996-01-01 00:00:00pages
80-3issue
1eissn
0003-9993issn
1532-821Xpii
S0003-9993(96)90225-7journal_volume
77pub_type
杂志文章abstract:OBJECTIVE:To examine whether high-intensity home-based respiratory muscle training, that is, with higher loads, delivered more frequently and for longer duration, than previously applied, would increase the strength and endurance of the respiratory muscles, reduce dyspnea and respiratory complications, and improve walk...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.apmr.2018.09.115
更新日期:2019-02-01 00:00:00
abstract::The blink reflex may be elicited in the orbicularis oculi following electrical stimulus to the periorbital regions. It consists of a direct early component (R1) and a late component (R2) which is both direct and consensual. The amplitudes of R1 and R2 are reduced and the latencies normal in patients with lesions affec...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract:OBJECTIVE:To assess muscle passive stiffness in medicated Parkinson's disease patients using myotonometry. DESIGN:Case-control study. SETTING:Kinesiology laboratory. PARTICIPANTS:Women with Parkinson's disease (PD) (n=8) and healthy matched elderly women (controls) (n=10) (mean age: PD, 77+/-3y; controls, 77+/-4y). ...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2010.01.012
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To investigate interlimb coupling in an adult population with left hemiplegia and an age-matched control group to better understand the unique motor control issues in stroke rehabilitation. DESIGN:A chi-square analysis was performed to compare the distribution of participants adopting a given movement patter...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2003.08.084
更新日期:2004-04-01 00:00:00
abstract::Because back pain is a widespread and costly condition that tends to recur, treatment must focus on both the amelioration of acute symptoms and prevention over the long term. This paper reports a longitudinal evaluation of a program from a community hospital that emphasizes both these aspects. One hundred twenty patie...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1988-08-01 00:00:00
abstract:UNLABELLED:This self-directed learning module highlights common comorbidities found in people with amputations and their impact on functional outcome. It is part of the study guide on limb deficiency and vascular rehabilitation in the Self-Directed Physiatric Education Program for practitioners and trainees in physical...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章,评审
doi:10.1016/j.apmr.2005.11.025
更新日期:2006-03-01 00:00:00
abstract::The halo traction device for cervical spine immobilization has few complications and is routinely used for spinal cord injured patients. The following case report describes a patient with lower cervical and upper thoracic fractures stabilized with a halo. She completed a two-month rehabilitation program without compli...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1992-05-01 00:00:00
abstract::Muscle pain syndrome is a complicated situation in that even an extensive work-up may overlook the primary etiology. A patient with multiple medical problems, including a history of partial gastrectomy due to trauma, a below-knee amputation from arteriosclerotic disease, and chronic phenytoin therapy for a seizure dis...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1991-09-01 00:00:00
abstract:UNLABELLED:This learner-directed module on spinal cord injury (SCI) presents a variety of perspectives of the process of personal and environmental adaptation for reintegration. Adaptation is unique to each person and does not predictably follow stages. Models used for understanding the process include biopsychosocial,...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章,评审
doi:10.1053/apmr.2002.32178
更新日期:2002-03-01 00:00:00
abstract::Ulnar motor and sensory nerve conduction velocities (NCV) were studied bilaterally in 20 able-bodied subjects for below elbow (BE) and across elbow (AE) segments to assess the effect of 4 different elbow positions on NCV (0 degrees, 45 degrees, 90 degrees, and 135 degrees). Although constant skin stimulation marker po...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1983-05-01 00:00:00
abstract::The symptoms of urinary incontinence, ataxia, and mental confusion are an integral part of the clinical presentation of normal pressure hydrocephalus (NPH). They are also common presentations in the rehabilitation setting of patients who have had a cerebral vascular accident. The concurrence of these entities challeng...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/s0003-9993(97)90069-1
更新日期:1997-09-01 00:00:00
abstract:OBJECTIVE:To evaluate if allocation concealment and intention-to-treat (ITT) analysis influence the treatment effects of physical therapy interventions in low back pain (LBP) trials. DATA SOURCES:We searched on PubMed, Embase, Cochrane Database of Systematic Reviews, Physiotherapy Evidence Database (PEDro), and CINAHL...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.apmr.2018.12.036
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the validity of the Prosthetic Upper Extremity Functional Index (PUFI), a parent- and older child-report measure that evaluates the extent of Prosthetic limb use, ease of task performance with and without the prosthesis, and its usefulness. DESIGN:Evaluation of discriminant validity (the PUFI's a...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1053/ampr.2003.50127
更新日期:2003-04-01 00:00:00
abstract:UNLABELLED:Liang C-C, Hsieh T-C, Lin C-H, Wei Y-C, Hsiao J, Chen J-C. Effectiveness of thermal stimulation for the moderately to severely paretic leg after stroke: serial changes at one-year follow-up. OBJECTIVE:To evaluate the serial changes of long-term effects of thermal stimulation (TS) on acute stroke patients. ...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.apmr.2012.06.016
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:To investigate the association between propulsion biomechanics, including variables that describe smoothness of the applied forces, and shoulder pain in individuals with spinal cord injury (SCI). DESIGN:Cross-sectional, observational study. SETTING:Non-university research institution. PARTICIPANTS:Communit...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2020.10.114
更新日期:2020-11-05 00:00:00
abstract:OBJECTIVE:To investigate the postural alignment of the upper body in the sagittal plane during sitting and standing postures as pregnancy progressed and then in the postpartum period. DESIGN:Longitudinal, repeated-measures design. SETTING:Biomechanics laboratory in an Australian university. PARTICIPANTS:A volunteer ...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1053/apmr.2002.36069
更新日期:2002-12-01 00:00:00
abstract::Patients with viable phrenic nerves and adequate diaphragm and lung function can be freed from mechanical ventilation by the use of phrenic nerve pacers. Four quadriplegic patients with phrenic nerve pacers were admitted to a rehabilitation facility between April 1981 and September 1986. These patients made significan...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1989-07-01 00:00:00
abstract::This study examined the extent of kinematic symmetry of lower limbs when walking. Twelve able-bodied subjects were measured with a device which recorded three-dimensional motion of hip and knee joints bilaterally. Comparisons of right and left sagittal, transverse, and coronal plane motions were conducted in the time ...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1984-04-01 00:00:00
abstract:OBJECTIVE:To examine the perspective of survivors of traumatic brain injury (TBI) regarding the extent and nature of their recovery over time. DESIGN:Inception cohort, longitudinal study. SETTING:Level I trauma center. PARTICIPANTS:One hundred fifty-seven consecutively hospitalized individuals with TBI (mean age, 36...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1053/apmr.2001.25082
更新日期:2001-08-01 00:00:00
abstract:OBJECTIVE:To summarize the literature on definitions, assessment protocols, and outcome measures for motor fatigability in patients with neurologic problems and investigates the known clinimetric properties according to the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) criteria....
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2019.11.015
更新日期:2020-05-01 00:00:00
abstract::A quadriplegic patient with obstructive emphysema caused by mucus in the bronchi of the hyperinflated lung, demonstrated by chest radiograph and corrected by bronchoscopic aspiration of secretions from the hyperexpanded side, is reported. Subsequently, this phenomenon recurred in the opposite lung. This case is of par...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract:OBJECTIVE:To establish the test-retest reliability of linear and nonlinear measures, including intra- and intersession reliability, when used to analyze the center of pressure (COP) time series during the development of infant sitting postural control in infants with or at risk for cerebral palsy (CP). DESIGN:Longitud...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2010.06.027
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVES:To examine the safety, feasibility, and balance performance effects of a 4-week home-based balance therapy program using a commercially available videogame system. DESIGN:A pilot study involving a preintervention and postintervention design was conducted with measurements taken at baseline, immediately post...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2011.08.031
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:(1) To identify significant changes in disability and quality of life (QOL) across 3 time points (t1: admission to rehabilitation; t2: 6wk postdischarge; t3: 6mo postdischarge) in individuals with lower limb amputation, and (2) to examine whether goal pursuit and goal adjustment at t1 were predictive of these...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2013.08.011
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To determine whether different foot orthoses have a similar effect on foot kinematics in subjects with subtalar osteoarthritis (OA) when walking on various ground conditions. DESIGN:Within-subject comparison study. SETTING:Biomechanics research laboratory. PARTICIPANTS:Ten subjects with unilateral subtalar...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2006.03.021
更新日期:2006-08-01 00:00:00
abstract::Fifty-six shoulders in 50 patients with adhesive capsulitis were divided into 2 groups, using different treatment programs. Group A comprised 28 shoulders in 26 patients. These were treated by therapeutic heating modalities followed by therapeutic exercises and gentle rhythmic stabilization manipulation. Group B total...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::Since much of medical rehabilitation is actually training which is focused on helping the patient and/or his/her family become active in the patient's daily care, the addition of the educational frame of reference can make rehabilitation professionals more effective. A recommended model for patient-family education ha...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1978-05-01 00:00:00
abstract::Herpes zoster infection, resulting from reactivation of the dormant varicella zoster virus in the dorsal root ganglia, usually causes a painful dermatomal vesicular rash. Rarely, associated peripheral motor weakness is present, the mechanism of which is unclear. Three patients are reported who had focal limb muscle we...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/s0003-9993(97)90204-5
更新日期:1997-08-01 00:00:00
abstract:OBJECTIVE:To compare participation and subjective experience of participants in both home-based multiuser virtual reality (VR) therapy and home-based single-user (SU) VR therapy. DESIGN:Crossover, randomized trial. SETTING:Initial training and evaluations occurred in a rehabilitation hospital; the interventions took ...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.apmr.2019.10.182
更新日期:2020-02-01 00:00:00
abstract::Reflex sympathetic dystrophy (RSD) has been described primarily in the upper extremity and is infrequently considered part of the differential diagnosis of postamputation pain. The manifestations of autonomic dysfunction may mimic other potential diagnoses of postoperative stump pain. We report a 47-year-old man who d...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1990-02-01 00:00:00