The mast cell: distribution and maturation in the peritoneal cavity of the adult rat.

Abstract:

:In the peritoneal cavity of the adult rat mast cells at the four stages of progressive maturation (and corresponding increase of sulphation of granules) are best demonstrated in free peritoneal fluid. Of the 0.1-0.2x10(6) cells in the free fluid, 26% are at stage 1 of maturation (all granules are stained by Alcian blue). 24% at stage 2 (majority of granules are stained by Alcian blue, minority by safranin), 20% at stage 3 (majority of granules are safranin-positive), and 30% at stage 4 (all granules are safranin-positive). Peritoneal washings yield a mean of about 1.3-1.8x10(6) mast cells of which 16% are at stage 1, 24% at stage 2, 34% at stage 3 and 26% at stage 4. The greater number recovered by washing, compared with the number in free peritoneal fluid, suggests that a substantial number of mast cells lie on the surface of the peritoneal membranes.

journal_name

Pathology

journal_title

Pathology

authors

Yong LC,Watkins S,Wilhelm DL

doi

10.3109/00313027509081687

subject

Has Abstract

pub_date

1975-10-01 00:00:00

pages

307-18

issue

4

eissn

0031-3025

issn

1465-3931

journal_volume

7

pub_type

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