Abstract:
:Effects of the SH inhibitor sodium iodoacetate, alone and with adjuncts menadiol diphosphate, sodium malonate, sodium fluoride and heparin, on incorporation of tryptophane-3 H into nonhistone chromosomal proteins of HeLa cells were examined. The drugs block incorporation of tryptophane-3 H into nonhistone chromosomal proteins far more than incorporation of leucine-3 H into total cellular proteins. Drug effects on thymidine phosphorylation and DNA synthesis in HeLa cells exceed corresponding effects on fibroblasts from normal healing wounds.
journal_name
Oncologyjournal_title
Oncologyauthors
Knock FE,Stein GS,Davis J,Galt RM,Oester YT,Sylvester Rdoi
10.1159/000225079subject
Has Abstractpub_date
1975-01-01 00:00:00pages
291-301issue
5-6eissn
0030-2414issn
1423-0232journal_volume
32pub_type
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