Abstract：
:In a community-based prospective study of 380 children conducted between 1987 and 1990, the rate of diarrhea was significantly associated with percentage of CD8 T-lymphocytes and the CD4:CD8 ratio. After adjustment for age and previous diarrhea, the relative incidence of diarrhea with a duration of > or = 7 days was 2.10 (95% confidence interval (CI) 1.15-3.85) in children with 20-29.9% CD8 T-cells and 3.41 (95% CI 1.29-9.01) in children with > or = 30% CD8 T-cells (in comparison with children who had less than 20% CD8 cells) (p for trend = 0.004). There was a nonsignificant tendency for rates of diarrhea of > or = 7 days to decrease according to increasing proportions of CD4 cells (p = 0.194). The authors found no significant association between T-cell subsets and diarrhea which resolved within 6 days. The association between the incidence of prolonged diarrhea and T-cell subset proportions could not be explained as a confounding effect of low weight, breastfeeding, or previous infection with measles or Cryptosporidium. However, other prior infections or micronutrient deficiencies may explain the findings, and these host factors may be significant targets in intervention against diarrheal diseases.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Mølbak K,Lisse IM,Aaby Pdoi
10.1093/oxfordjournals.aje.a008660subject
Has Abstractpub_date
1996-01-01 00:00:00pages
79-84issue
1eissn
0002-9262issn
1476-6256journal_volume
143pub_type
杂志文章abstract：:Investigations of gene (G)-environment (E) interactions have led to limited findings to date, possibly due to weak effects of individual genetic variants. Polygenic risk scores (PRS), which capture the genetic susceptibility associated with a set of variants, can be a powerful tool for detecting global patterns of int...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwz175
更新日期：2019-11-01 00:00:00
abstract：:Although data on the prevalence of injection drug use are an essential prerequisite for estimating the number of individuals infected with the human immunodeficiency virus (HIV), there have been few attempts to utilize statistical methods of population estimation based on multiple data sources. Data on 3,670 cases (2,...
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pub_type： 杂志文章
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更新日期：1993-08-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117222
更新日期：1994-07-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwr146
更新日期：2011-10-01 00:00:00
abstract：:Although the percentage of US drivers with valid driver's licenses varies from state to state, it has historically been high enough to constitute a useful sampling frame for many public health purposes. Over the past decade, states have had to restrict access to this information to comply with the Driver's Privacy Pro...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwr018
更新日期：2011-06-15 00:00:00
abstract：:Recent developments in population mathematics apply to measurement issues in epidemiology. In particular, they demonstrate explicitly the relations that prevail among incidence, prevalence, case-fatality, mortality, and duration of illness in a population at a moment in time, rather than in a cohort of persons followe...
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pub_type： 杂志文章
doi：10.1093/aje/126.2.336
更新日期：1987-08-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113293
更新日期：1982-02-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/152.11.1017
更新日期：2000-12-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwf138
更新日期：2002-11-15 00:00:00
abstract：:This case-control study evaluated the risk of epithelial ovarian cancer associated with genital exposure to various forms of powder application. Cases included all women aged 20-79 years in three counties of western Washington who were diagnosed with borderline or invasive ovarian cancer from 1986 through 1988; 64.3% ...
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pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009128
更新日期：1997-03-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 临床试验,杂志文章,多中心研究,评审
doi：10.1093/oxfordjournals.aje.a116264
更新日期：1992-01-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwv300
更新日期：2016-06-01 00:00:00
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pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a112341
更新日期：1976-12-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009512
更新日期：1998-04-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kww086
更新日期：2016-11-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114665
更新日期：1987-07-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwx358
更新日期：2018-06-01 00:00:00
abstract：:Using 1973-2000 mesothelioma incidence data released by the Surveillance, Epidemiology, and End Results Program in April 2003, the authors estimated the parameters of a birth-cohort and age model to determine whether previously reported patterns of mesothelioma in the United States have changed. Compared with analyses...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwh025
更新日期：2004-01-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwp351
更新日期：2010-01-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：2006-09-15 00:00:00
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pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a115048
更新日期：1988-11-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwx055
更新日期：2017-07-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：2012-07-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/155.2.159
更新日期：2002-01-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：2020-07-08 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：2016-05-15 00:00:00
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pub_type： 杂志文章
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更新日期：1989-11-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114858
更新日期：1988-04-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 历史文章,杂志文章
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更新日期：2003-10-15 00:00:00
abstract：:Trends in sexual behavior associated with incident infection with human immunodeficiency virus (HIV) type 1 are described and a case-control study was conducted to examine risk factors for HIV seroconversion in homosexual men who became infected with HIV between 1982 and 1994 from four geographic sites: Amsterdam, the...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009311
更新日期：1997-10-01 00:00:00
