Recombinant proteins for medical use: the attractions and challenges.

Abstract:

:Recombinant proteins that have survived the challenges of process development and clinical trials are becoming blockbuster medical products. Growth factors, enzymes and antibodies are being improved by mutational approaches, fused with other proteins, and even chemically modified in vitro. Drug development and testing approaches have advanced, and proteins produced in transgenic animals are new becoming available. Future protein products might include cancer vaccines and therapies for a variety of genetic diseases, but alternative treatments involving gene therapy or small synthetic compounds will provide competition.

journal_name

Curr Opin Biotechnol

authors

Koths K

doi

10.1016/0958-1669(95)80112-x

subject

Has Abstract

pub_date

1995-12-01 00:00:00

pages

681-7

issue

6

eissn

0958-1669

issn

1879-0429

pii

0958-1669(95)80112-X

journal_volume

6

pub_type

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