Complete response of transverse colon carcinoma to S1, a new chemotherapy agent: report of a case.

Abstract:

:A complete response to a new chemotherapeutic agent, S1, was achieved in a 64-year-old Japanese man with advanced transverse colon cancer. S1 is a combination of the agents tegafur, 5-chloro-2,4-dihydroxypyridine, and oxonic acid. Because the patient was considered to be a high operative risk due to his poor general condition, S1 was administered at 100 mg/day for 5 days/week over 12 weeks. However, as the serum carcinoembryonic antigen level continued to gradually increase, partial resection of the transverse colon was finally performed. Histopathological study of the resected specimen showed mucin pools in the colon wall with no residual viable cancer cells. No perioperative complications were recognized and the patient is now leading a normal life 6 months after his operation without any signs of recurrence.

journal_name

Surg Today

journal_title

Surgery today

authors

Mimori K,Mori M,Baba H,Maehara Y,Sugimachi K

doi

10.1007/BF00311492

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

741-4

issue

8

eissn

0941-1291

issn

1436-2813

journal_volume

25

pub_type

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