Comparison of arterialized and nonarterialized orthotopic liver transplantation in mice: prowess or relevant model?

abstract：:Lamivudine combined with hepatitis B immune globulin (HBIg) is the standard of care for preventing the recurrence hepatitis B virus after liver transplant. To determine the risk of hepatitis B virus (HBV) recurrence after early withdrawal of HBIg in patients receiving lamivudine maintenance therapy, 20 patients receiv...

journal_title：Transplantation

authors： Buti M,Mas A,Prieto M,Casafont F,González A,Miras M,Herrero JI,Jardi R,Esteban R

更新日期：2007-09-15 00:00:00

abstract：BACKGROUND:During the isolation process, pancreatic islets are exposed to an environment of sterile inflammation resulting in an upregulated inflammatory state before transplantation. Toll-like receptor 4 (TLR4) has been identified as a major mediator of sterile inflammation. Therefore, we sought to determine whether e...

journal_title：Transplantation

authors： Chang CA,Murphy K,Kane RR,Lawrence MC,Naziruddin B

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:This study is designed to examine a possible association of cardiopulmonary bypass (CPB) support and outcome of lung transplantation in a well-balanced group of emphysema patients. METHODS:We performed a retrospective analysis of 62 consecutive primary bilateral lung transplantations for emphysema. Risk fac...

journal_title：Transplantation

authors： de Boer WJ,Hepkema BG,Loef BG,van der Bij W,Verschuuren EA,de Vries HJ,Lems SP,Ebels T

更新日期：2002-05-27 00:00:00

abstract：:Hepatitis C viral recurrence after orthotopic liver transplantation is almost universal. Hepatitis C induced graft failure may occur, but the clinical and histologic profiles are not well defined. The aim of this study was to describe the pattern of early graft failure in patients with recurrent hepatitis C after live...

journal_title：Transplantation

authors： Dickson RC,Caldwell SH,Ishitani MB,Lau JY,Driscoll CJ,Stevenson WC,McCullough CS,Pruett TL

更新日期：1996-03-15 00:00:00

abstract：:Rejection crises after kidney transplantation could be associated with individual variability of pharmacokinetic parameters of steroids. We therefore investigated the individual pharmacokinetics of methylprednisolone on day 2 (60 mg intravenously) and day 4 (60 mg per os) in 40 patients after kidney transplantation. M...

journal_title：Transplantation

authors： Keller F,Hemmen T,Schöneshöfer M,Schwarz A,Offermann G

更新日期：1995-08-27 00:00:00

abstract：:World Kidney Day on March 8, 2012, provides a chance to reflect on the success of kidney transplantation as a therapy for end-stage kidney disease that surpasses dialysis treatments both for the quality and quantity of life that it provides and for its cost-effectiveness. Anything that is both cheaper and better, but ...

journal_title：Transplantation

authors： Garcia GG,Harden P,Chapman J,World Kidney Day Steering Committee 2012.

更新日期：2012-02-27 00:00:00

abstract：BACKGROUND:Bone complications after hematopoietic stem-cell transplantation (HSCT) are relatively frequent. Evaluation of biomarkers of bone turnover and dual energy x-ray absorptiometry (DEXA) are not known in this context. METHODS:We prospectively evaluated bone mineral density, biomarkers of bone turnover, and the ...

journal_title：Transplantation

authors： Petropoulou AD,Porcher R,Herr AL,Devergie A,Brentano TF,Ribaud P,Pinto FO,Rocha V,Peffault de Latour R,Orcel P,Socié G,Robin M

更新日期：2010-06-15 00:00:00

abstract：:Since the earliest days of transplantation, immunobiologists have sought means to prevent recognition and rejection of foreign tissue. The goal of these strategies is the retention of recipient immune function while selectively avoiding graft injury. Although considerable theoretical and technical problems remain, an ...

journal_title：Transplantation

authors： Lynch RJ,Platt JL

更新日期：2009-12-15 00:00:00

abstract：BACKGROUND:Human ehrlichiosis, a newly described zoonotic infection, can be classified as human monocytic ehrlichiosis (HME) or human granulocytic ehrlichiosis (HGE). Although the clinical manifestations of HME and HGE are similar, the type of leukocyte infected, the etiologic agent, and the tick vector are distinct. ...

journal_title：Transplantation

authors： Adachi JA,Grimm EM,Johnson P,Uthman M,Kaplan B,Rakita RM

更新日期：1997-10-27 00:00:00

abstract：:Despite improvements in immunosuppression, rejection occurs in 50% of liver transplant patients and may cause significant morbidity. The most frequent cause of death after liver transplantation is severe infection. Determination of the cytokine network may lead to earlier detection of patients at risk for severe rejec...

journal_title：Transplantation

authors： Platz KP,Mueller AR,Rossaint R,Steinmüller T,Lemmens HP,Lobeck H,Neuhaus P

更新日期：1996-11-27 00:00:00

abstract：:Although ELISA on purified HLA molecules for detecting anti-HLA antibody (P-S ELISA) does detect some antibodies previously missed by the conventional complement dependent cytotoxicity method (C Cytotox), HLA ELISA should not fail to detect antibodies already detected by the conventional reference method to be able to...

journal_title：Transplantation

authors： Pierquin A,Masson D,Toupance O,Tabary T,Bougy F,Bensa JC,Chanard J,Cohen JH

更新日期：1996-11-27 00:00:00

abstract：BACKGROUND:Humanized Fc receptor (FcR)-nonbinding antibodies against CD3 are promising immunosuppressive agents that may overcome both the neutralizing response to and the cytokine release syndrome seen with conventional monoclonal antibodies against CD3. In addition, evidence from several murine models suggests that t...

journal_title：Transplantation

authors： Chau LA,Tso JY,Melrose J,Madrenas J

更新日期：2001-04-15 00:00:00

abstract：BACKGROUND:Bone marrow cells (BMCs) are believed to have the ability to generate functional hepatocytes and have some merits as a therapeutic modality for metabolic liver diseases. However, the appearance of BMC-derived hepatocytes (BMDHs) is low. We hypothesized that early BMC injection would be feasible for creating ...

journal_title：Transplantation

authors： Misawa R,Soeda J,Ise H,Takahashi M,Kubota K,Mita A,Nakata T,Miyagawa S

更新日期：2009-04-27 00:00:00

abstract：UNLABELLED:Most isolated intestinal graft losses are immunological. We conducted a pilot study to evaluate the feasibility of national sharing of HLA no-mismatch allografts for cadaveric isolated intestinal transplantation. METHODS:UNOS data were analyzed in a theoretical model. Part I: All solid organ donors between ...

journal_title：Transplantation

authors： Fishbein TM,Bodian CA,Miller CM

更新日期：2000-03-15 00:00:00

abstract：:Hemorrhagic cystitis (HC) is a major cause of morbidity after BMT; we have analyzed its incidence, risk factors, and complications in 977 patients undergoing BMT between 1974 and 1988. Despite vigorous hydration and frequent voiding in all patients receiving cyclophosphamide, 135/977 (15% by Kaplan-Meier projection) d...

journal_title：Transplantation

authors： Sencer SF,Haake RJ,Weisdorf DJ

更新日期：1993-10-01 00:00:00

abstract：:In the USA approximately 10% of candidates for renal transplantation have serum antibodies to hepatitis C (HCV). To assess the possible impact of HCV infection on early posttransplant events we assessed allograft complications during the first 6 months following renal transplantation in three groups of adult renal all...

journal_title：Transplantation

authors： Cosio FG,Sedmak DD,Henry ML,Al Haddad C,Falkenhain ME,Elkhammas EA,Davies EA,Bumgardner GL,Ferguson RM

更新日期：1996-10-27 00:00:00

abstract：BACKGROUND:Recurrent hepatitis C virus (HCV) after liver transplantation (OLT) is a major cause of graft loss in HCV-positive patients. In this study, we evaluated the efficacy and safety of pegylated interferon alfa-2b (peginterferon) and ribavirin treatment for recurrent HCV after OLT and analyzed the influence of an...

journal_title：Transplantation

authors： Neumann U,Puhl G,Bahra M,Berg T,Langrehr JM,Neuhaus R,Neuhaus P

更新日期：2006-07-15 00:00:00

abstract：BACKGROUND:Donor hepatectomy with maximal safety while preserving graft viability is of principal concern in living donor liver transplantation. There are compelling reasons for avoiding blood transfusion, even with autologous blood, to avoid the potential risks it imposes on healthy donors. This study aims to describe...

journal_title：Transplantation

authors： Chen CL,Chen YS,de Villa VH,Wang CC,Lin CL,Goto S,Wang SH,Cheng YF,Huang TL,Jawan B,Cheung HK

更新日期：2000-06-27 00:00:00

abstract：BACKGROUND:Malnutrition is common in patients with end-stage liver disease considered for transplantation, but it is unclear whether this affects the outcome after transplantation. AIM.: To determine whether the severity of malnutrition in liver transplant candidates affects outcome after transplantation. METHODS:We d...

journal_title：Transplantation

authors： Shahid M,Johnson J,Nightingale P,Neuberger J

更新日期：2005-02-15 00:00:00

abstract：BACKGROUND:Despite effective antiviral treatment, hundreds of kidneys from deceased donors with hepatitis C virus (HCV) are discarded annually. Little is known about the determinants of willingness to accept HCV-infected kidneys among HCV-negative patients. METHODS:At 2 centers, 189 patients undergoing initial or reev...

journal_title：Transplantation

authors： McCauley M,Mussell A,Goldberg D,Sawinski D,Molina RN,Tomlin R,Doshi SD,Abt P,Bloom R,Blumberg E,Kulkarni S,Esnaola G,Shults J,Thiessen C,Reese PP

更新日期：2018-04-01 00:00:00

abstract：:The effect of the tritiated thymidine (3H-TdR) suicide technique on the ability of donor cells to induce fatal graft-versus-host disease (GVHD) was studied. C57BL/6 (H-2b) spleen cells were stimulated in vitro with irradiated BALB/c (H-2d) Moloney lymphoma cells in mixed culture and 3H-TdR of high-specific activity ad...

journal_title：Transplantation

authors： Cheever MA,Einstein AB Jr,Kempf RA,Fefer A

更新日期：1977-04-01 00:00:00

abstract：BACKGROUND:Graft thrombosis immediately after surgery remains a problem for successful pancreas transplantation. The present study evaluated the efficacy of computed tomography (CT) angiography for monitoring of graft patency in the immediate postoperative period. METHODS:The study involved 119 patients who underwent ...

journal_title：Transplantation

authors： Kim YH,Park JB,Lee SS,Byun JH,Kim SC,Han DJ

更新日期：2012-11-15 00:00:00

abstract：BACKGROUND:Several technical modifications in portal vein (PV) reconstruction have shown excellent outcomes in pediatric liver transplantation (LT); however, which procedure is the best for PV reconstruction of the hypoplastic PV in pediatric LT remains unclear. METHODS:One hundred sixteen pediatric patients aged 1 or...

journal_title：Transplantation

authors： Sakamoto S,Uchida H,Kitajima T,Shimizu S,Yoshimura S,Takeda M,Hirata Y,Fukuda A,Kasahara M

更新日期：2020-01-01 00:00:00

abstract：:We developed and applied a quantitative competitive polymerase chain reaction method to study the expression of various cytokine genes in Con A-stimulated murine splenocytes. This method relies on the use of competitive templates that differ from the target cytokine cDNA templates only by the introduction of a unique ...

journal_title：Transplantation

authors： Zheng XX,Strom TB,Steele AW

更新日期：1994-07-15 00:00:00

abstract：:The beneficial effect of deoxyspergualin (DSG, NKT-01) on lethal graft-versus-host disease in mice has been studied in a major histoincompatible donor-recipient combination. Suppression of the effector mechanisms responsible for the lethal outcome in this GVHD model is also noted. This study reveals: (1) DSG has a mar...

journal_title：Transplantation

authors： Nemoto K,Hayashi M,Ito J,Sugawara Y,Mae T,Fujii H,Abe F,Fujii A,Takeuchi T

更新日期：1991-03-01 00:00:00

abstract：:A new method of thymus transplantation is introduced, in which the graft is directly connected with the recipient's vascular system. This procedure was used both in euthymic rats and congenitally athymic nude rats. At all tested intervals after transplantation thymus grafts hardly differed from the recipient's own thy...

journal_title：Transplantation

authors： Kampinga J,Schuurman HJ,Pol GH,Bartels H,Broekhuizen R,Vaessen LM,Tielen FJ,Rozing J,Blaauw EH,Roser B

更新日期：1990-10-01 00:00:00

abstract：:Using antisera to human beta2-microglobulin and an immunofluorescent technique, beta2-microglobulin was found to be localized along tubular and glomerular basement membranes of renal bipsies studied. Since beta2-microglobulin is a subunit of HLA preparations, it may also serve as an indirect marker for the presence of...

journal_title：Transplantation

authors： Ooi BS,Rubin SC,Pesce AJ,Pollak VE

更新日期：1977-07-01 00:00:00

abstract：:One of the most powerful influences on cadaveric renal graft survival is the enhancing effect of blood transfusions from unrelated individuals (1, 2). However, the optimum number of transfusions required to achieve this effect remains controversial. Enhanced graft survival following only one or two transfusions has be...

journal_title：Transplantation

authors： Martin S,Dyer PA,Harris R,Manos J,Mallick NP,Gokal R,Johnson RW

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:BK polyomavirus infection has been reported in 10% to 60% of renal transplant recipients with progression to BK nephropathy (BKN) occurring in 1% to 5% of patients. Graft loss occurs in up to 60% of renal transplant recipients with BKN. Because BK polyomavirus infection is believed, in part, to be a manifest...

journal_title：Transplantation

authors： Guasch A,Roy-Chaudhury P,Woodle ES,Fitzsimmons W,Holman J,First MR,FK778 BK Nephropathy Study Group.

更新日期：2010-10-27 00:00:00

abstract：:In a canine model of acute ischemic lung injury, a hypertonic citrate solution (HTC) widely used for renal preservation in the United Kingdom, was compared with modified Euro-Collins' solution (ECS) currently the most widely clinically used pulmonary perfusate. Ten beagle dogs underwent left thoracotomy and exclusion ...

journal_title：Transplantation

authors： Hooper TL,Jones MT,Thomson DS,Cook L,Owen S,Wilkes S,Woodcock A,Webster AH,Hasleton P,McGregor CG

更新日期：1991-05-01 00:00:00